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Cancer survivors face elevated rates of depression, anxiety, and general emotional distress, yet the precise moments they most need support are often the moments when self-report is sparse, a phenomenon we term the diary paradox. Passive…

Human-Computer Interaction · Computer Science 2026-05-19 Zhiyuan Wang , Ariful Islam , Indrajeet Ghosh , Xinyu Chen , Katharine E. Daniel , Subigya Nepal , Philip Chow , Laura E. Barnes

At the heart of medicine lies the physician-patient dialogue, where skillful history-taking paves the way for accurate diagnosis, effective management, and enduring trust. Artificial Intelligence (AI) systems capable of diagnostic dialogue…

Large Language Models (LLMs) have advanced recommendation capabilities through enhanced reasoning, but pose significant challenges for real-world deployment due to high inference costs. Conversely, while Small Language Models (SLMs) offer…

Computation and Language · Computer Science 2025-10-13 Prosenjit Biswas , Pervez Shaik , Abhinav Thorat , Ravi Kolla , Niranjan Pedanekar

Medical dialogue systems have attracted significant attention for their potential to act as medical assistants. Enabling these medical systems to emulate clinicians' diagnostic reasoning process has been the long-standing research focus.…

Computation and Language · Computer Science 2024-06-21 Kaishuai Xu , Yi Cheng , Wenjun Hou , Qiaoyu Tan , Wenjie Li

Vision impairment and blindness are a major global health challenge where gaps in the ophthalmology workforce limit access to specialist care. We evaluate AMIE, a medically fine-tuned conversational system based on Gemini with integrated…

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

In the evolving landscape of human-centered AI, fostering a synergistic relationship between humans and AI agents in decision-making processes stands as a paramount challenge. This work considers a problem setup where an intelligent agent…

Artificial Intelligence · Computer Science 2024-09-11 Sören Schleibaum , Lu Feng , Sarit Kraus , Jörg P. Müller

Clinical decision-making is inherently complex, often influenced by cognitive biases, incomplete information, and case ambiguity. Large Language Models (LLMs) have shown promise as tools for supporting clinical decision-making, yet their…

Machine Learning · Computer Science 2025-07-10 Burcu Sayin , Ipek Baris Schlicht , Ngoc Vo Hong , Sara Allievi , Jacopo Staiano , Pasquale Minervini , Andrea Passerini

Artificial intelligence (AI) has demonstrated strong potential in clinical diagnostics, often achieving accuracy comparable to or exceeding that of human experts. A key challenge, however, is that AI reasoning frequently diverges from…

Artificial Intelligence · Computer Science 2026-05-25 Belona Sonna , Alban Grastien

The integration of voice-based AI agents in healthcare presents a transformative opportunity to bridge economic and accessibility gaps in digital health delivery. This paper explores the role of large language model (LLM)-powered voice…

Artificial Intelligence · Computer Science 2025-07-28 Bo Wen , Chen Wang , Qiwei Han , Raquel Norel , Julia Liu , Thaddeus Stappenbeck , Jeffrey L. Rogers

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

Human-Computer Interaction · Computer Science 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Artificial intelligence (AI)-based decision support systems can be highly accurate yet still fail to support users or improve decisions. Existing theories of AI-assisted decision-making focus on calibrating reliance on AI advice, leaving it…

Human-Computer Interaction · Computer Science 2026-02-03 Venkatesh Sivaraman , Eric P. Mason , Mengfan Ellen Li , Jessica Tong , Andrew J. King , Jeremy M. Kahn , Adam Perer

We developed a voice-driven artificial intelligence (AI) system that guides anyone - from paramedics to family members - through expert-level stroke evaluations using natural conversation, while also enabling smartphone video capture of key…

The shortage of doctors is creating a critical squeeze in access to medical expertise. While conversational Artificial Intelligence (AI) holds promise in addressing this problem, its safe deployment in patient-facing roles remains largely…

Artificial Intelligence · Computer Science 2025-04-11 Antoine Lizée , Pierre-Auguste Beaucoté , James Whitbeck , Marion Doumeingts , Anaël Beaugnon , Isabelle Feldhaus

As the field of healthcare increasingly adopts artificial intelligence, it becomes important to understand which types of explanations increase transparency and empower users to develop confidence and trust in the predictions made by…

Artificial Intelligence · Computer Science 2025-05-16 Felix Liedeker , Olivia Sanchez-Graillet , Moana Seidler , Christian Brandt , Jörg Wellmer , Philipp Cimiano

Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored,…

Computation and Language · Computer Science 2025-03-11 Pengcheng Qiu , Chaoyi Wu , Shuyu Liu , Weike Zhao , Zhuoxia Chen , Hongfei Gu , Chuanjin Peng , Ya Zhang , Yanfeng Wang , Weidi Xie

Rare diseases affect over 300 million individuals worldwide, yet timely and accurate diagnosis remains an urgent challenge. Patients often endure a prolonged diagnostic odyssey exceeding five years, marked by repeated referrals,…

Computation and Language · Computer Science 2026-02-17 Weike Zhao , Chaoyi Wu , Yanjie Fan , Xiaoman Zhang , Pengcheng Qiu , Yuze Sun , Xiao Zhou , Yanfeng Wang , Xin Sun , Ya Zhang , Yongguo Yu , Kun Sun , Weidi Xie

Large Language Models (LLMs) have demonstrated great potential for conducting diagnostic conversations but evaluation has been largely limited to language-only interactions, deviating from the real-world requirements of remote care…

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