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Cardiac biosignals, such as electrocardiograms (ECG) and photoplethysmograms (PPG), are of paramount importance for the diagnosis, prevention, and management of cardiovascular diseases, and have been extensively used in a variety of…

Photoplethysmogram (PPG) and electrocardiogram (ECG) are commonly recorded in intesive care unit (ICU) and operating room (OR). However, the high incidence of poor, incomplete, and inconsistent signal quality, can lead to false alarms or…

Machine Learning · Computer Science 2025-09-16 Zongheng Guo , Tao Chen , Manuela Ferrario

Electroencephalography foundation models (EEG-FMs) have advanced brain signal analysis, but the lack of standardized evaluation benchmarks impedes model comparison and scientific progress. Current evaluations rely on inconsistent protocols…

Signal Processing · Electrical Eng. & Systems 2026-02-16 Wei Xiong , Jiangtong Li , Jie Li , Kun Zhu , Changjun Jiang

Blood pressure (BP) is a key indicator of cardiovascular health. As hypertension remains a global cause of morbidity and mortality, accurate, continuous, and non-invasive BP monitoring is therefore of paramount importance.…

Signal Processing · Electrical Eng. & Systems 2025-10-20 Bálint Tóth , Dominik Senti , Thorir Mar Ingolfsson , Jeffrey Zweidler , Alexandre Elsig , Luca Benini , Yawei Li

Tracking biosignals is crucial for monitoring wellness and preempting the development of severe medical conditions. Today, wearable devices can conveniently record various biosignals, creating the opportunity to monitor health status…

Machine Learning · Computer Science 2024-03-07 Salar Abbaspourazad , Oussama Elachqar , Andrew C. Miller , Saba Emrani , Udhyakumar Nallasamy , Ian Shapiro

We propose the Multimodal Clinical Benchmark for Emergency Care (MC-BEC), a comprehensive benchmark for evaluating foundation models in Emergency Medicine using a dataset of 100K+ continuously monitored Emergency Department visits from…

Machine Learning · Computer Science 2023-11-10 Emma Chen , Aman Kansal , Julie Chen , Boyang Tom Jin , Julia Rachel Reisler , David A Kim , Pranav Rajpurkar

Cardiovascular disease remains the leading cause of global mortality, yet scalable cardiac monitoring is hindered by the gap between diagnostic-rich ECG and ubiquitous wearable PPG. Bridging this gap requires representations that are…

Machine Learning · Computer Science 2026-05-12 Zhangdaihong Liu , Chang Liu , Fenglin Liu , Yixuan Chen , Yang Yang , David A. Clifton , Xiao Gu

Electrocardiogram~(ECG), a key bioelectrical time-series signal, is crucial for assessing cardiac health and diagnosing various diseases. Given its time-series format, ECG data is often incorporated into pre-training datasets for…

Signal Processing · Electrical Eng. & Systems 2026-02-26 Zhijiang Tang , Jiaxin Qi , Yuhua Zheng , Jianqiang Huang

Physiological foundation models (FMs) have shown promise for biosignal representation learning, yet most remain confined to a single modality such as EEG, ECG, or PPG, largely because paired multimodal datasets are scarce. In this paper, we…

Artificial Intelligence · Computer Science 2026-04-07 Marija Zelic , Anna Tegon , Yawei Li , Thorir Mar Ingolfsson , Luca Benini

Physiological signals such as electrocardiograms (ECG) and electroencephalograms (EEG) provide complementary insights into human health and cognition, yet multi-modal integration is challenging due to limited multi-modal labeled data, and…

While recent multimodal large language models (MLLMs) have advanced automated ECG interpretation, they still face two key limitations: (1) insufficient multimodal synergy between time series signals and visual ECG representations, and (2)…

Computation and Language · Computer Science 2025-10-21 Xiang Lan , Feng Wu , Kai He , Qinghao Zhao , Shenda Hong , Mengling Feng

The electrocardiogram (ECG) is a cost-effective, highly accessible and widely employed diagnostic tool. With the advent of Foundation Models (FMs), the field of AI-assisted ECG interpretation has begun to evolve, as they enable model reuse…

Artificial Intelligence · Computer Science 2026-01-30 Francesca Filice , Edoardo De Rose , Simone Bartucci , Francesco Calimeri , Simona Perri

Timely access to laboratory values is critical for clinical decision-making, yet current approaches rely on invasive venous sampling and are intrinsically delayed. Electrocardiography (ECG), as a non-invasive and widely available signal,…

Machine Learning · Computer Science 2025-10-28 Yujie Xiao , Gongzhen Tang , Wenhui Liu , Jun Li , Guangkun Nie , Zhuoran Kan , Deyun Zhang , Qinghao Zhao , Shenda Hong

This study proposes a novel perspective on multimodal deep learning for biomedical signal classification, systematically analyzing how complementary feature domains impact model performance. While fusing multiple domains often presumes…

Machine Learning · Computer Science 2025-08-05 Timothy Oladunni , Alex Wong

Foundation models (FMs) promise to extract unified representations that generalize across downstream tasks. They have emerged across fields, including electroencephalography (EEG), but it is less clear how effective they are in this…

Tasks ranging from sleep staging to clinical diagnosis traditionally rely on standard polysomnography (PSG) devices, bedside monitors and wearable devices, which capture diverse nocturnal biosignals (e.g., EEG, EOG, ECG, SpO$_2$). However,…

Machine Learning · Computer Science 2026-02-17 Weixuan Yuan , Zengrui Jin , Yichen Wang , Donglin Xie , Ziyi Ye , Chao Zhang , Xuesong Chen

Biomedical signal processing extract meaningful information from physiological signals like electrocardiograms (ECGs), electroencephalograms (EEGs), and electromyograms (EMGs) to diagnose, monitor, and treat medical conditions and diseases…

Signal Processing · Electrical Eng. & Systems 2025-08-13 Justin London

Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training…

Electroencephalogram (EEG) signals play a crucial role in understanding brain activity and diagnosing neurological diseases. Because supervised EEG encoders are unable to learn robust EEG patterns and rely too heavily on expensive signal…

Machine Learning · Computer Science 2025-09-23 Junhong Lai , Jiyu Wei , Lin Yao , Yueming Wang

The 12-lead electrocardiogram (ECG) is a long-standing diagnostic tool. Yet machine learning for ECG interpretation remains fragmented, often limited to narrow tasks or datasets. FMs promise broader adaptability, but fundamental questions…

Signal Processing · Electrical Eng. & Systems 2026-03-05 M A Al-Masud , Juan Miguel Lopez Alcaraz , Nils Strodthoff
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