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The integration of Artificial Intelligence (AI) into clinical settings presents a software engineering challenge, demanding a shift from isolated models to robust, governable, and reliable systems. However, brittle, prototype-derived…

A multi-agent AI system (MAS) is composed of multiple autonomous agents that interact, exchange information, and make decisions based on internal generative models. Recent advances in large language models and tool-using agents have made…

The design space of agentic AI inference spans two extremes: frontier large language models (LLMs), typically hosted in the cloud and offering strong performance across a wide range of tasks at substantially high cost, and more…

Multiagent Systems · Computer Science 2026-05-29 Corrado Rainone , Davide Belli , Bence Major , Arash Behboodi

Machine learning (ML) underpins foundation models in finance, healthcare, and critical infrastructure, making them targets for data poisoning, model extraction, prompt injection, automated jailbreaking, and preference-guided black-box…

Cryptography and Security · Computer Science 2025-12-30 Armstrong Foundjem , Lionel Nganyewou Tidjon , Leuson Da Silva , Foutse Khomh

Multi-agent collaboration systems (MACS), powered by large language models (LLMs), solve complex problems efficiently by leveraging each agent's specialization and communication between agents. However, the inherent exchange of information…

Cryptography and Security · Computer Science 2026-03-04 Jian Cui , Zichuan Li , Luyi Xing , Xiaojing Liao

AI agent protocols -- including MCP, A2A, ANP, and ACP -- enable autonomous agents to discover capabilities, delegate tasks, and compose services across trust boundaries. Despite massive deployment (MCP alone has 97M+ monthly SDK…

Cryptography and Security · Computer Science 2026-03-26 Shenghan Zheng , Qifan Zhang

Multi-agent systems (MAS) decompose complex tasks and delegate subtasks to different large language model (LLM) agents and tools. Prior studies have reported the superior accuracy performance of MAS across diverse domains, enabled by…

Multiagent Systems · Computer Science 2025-05-27 Mingyan Gao , Yanzi Li , Banruo Liu , Yifan Yu , Phillip Wang , Ching-Yu Lin , Fan Lai

This paper introduces Agentic-AI Healthcare, a privacy-aware, multilingual, and explainable research prototype developed as a single-investigator project. The system leverages the emerging Model Context Protocol (MCP) to orchestrate…

Cryptography and Security · Computer Science 2025-10-06 Mohammed A. Shehab

Agentic AI systems are entering software engineering workflows, yet empirical evidence on how industrial organizations actually adopt them remains sparse. We present a qualitative interview study with sixteen practitioners across twelve…

Software Engineering · Computer Science 2026-05-15 Spyridon Alvanakis Apostolou , Jan Bosch , Helena Holmström Olsson

Agentic AI marks a major shift in how autonomous systems reason, plan, and execute multi-step tasks. Unlike traditional single model prompting, agentic workflows integrate multiple specialized agents with different Large Language…

The A2AS framework is introduced as a security layer for AI agents and LLM-powered applications, similar to how HTTPS secures HTTP. A2AS enforces certified behavior, activates model self-defense, and ensures context window integrity. It…

Agentic AI systems, which leverage multiple autonomous agents and large language models (LLMs), are increasingly used to address complex, multi-step tasks. The safety, security, and functionality of these systems are critical, especially in…

Artificial Intelligence · Computer Science 2026-04-16 Edoardo Allegrini , Ananth Shreekumar , Z. Berkay Celik

Protecting cyberspace requires not only advanced tools but also a shift in how we reason about threats, trust, and autonomy. Traditional cybersecurity methods rely on manual responses and brittle heuristics. To build proactive and…

Cryptography and Security · Computer Science 2025-07-16 Quanyan Zhu

Cybersecurity has become one of the earliest adopters of agentic AI, as security operations centers increasingly rely on multi-step reasoning, tool-driven analysis, and rapid decision-making under pressure. While individual large language…

Cryptography and Security · Computer Science 2025-12-09 Vaishali Vinay

In an era where vast amounts of data are collected and processed from diverse sources, there is a growing demand for sophisticated AI systems capable of intelligently fusing and analyzing this information. To address these challenges,…

Software Engineering · Computer Science 2025-11-24 Amine Ben Hassouna , Hana Chaari , Ines Belhaj

Powerful autonomous systems, which reason, plan, and converse using and between numerous tools and agents, are made possible by Large Language Models (LLMs), Vision-Language Models (VLMs), and new agentic AI systems, like LangChain and…

Cryptography and Security · Computer Science 2025-12-30 Toqeer Ali Syed , Mishal Ateeq Almutairi , Mahmoud Abdel Moaty

A multi-agent system (MAS) powered by large language models (LLMs) can automate tedious user tasks such as meeting scheduling that requires inter-agent collaboration. LLMs enable nuanced protocols that account for unstructured private data,…

Artificial Intelligence · Computer Science 2025-10-17 Mason Nakamura , Abhinav Kumar , Saaduddin Mahmud , Sahar Abdelnabi , Shlomo Zilberstein , Eugene Bagdasarian

Operating LLMs as coordinated multi-agent research systems over multi-hour runs surfaces failure modes that single-shot evaluation cannot: upstream providers throttle without warning, sub-agents drift the task to fit accessible tools,…

Artificial Intelligence · Computer Science 2026-05-26 Sasank Annapureddy

AI agents powered by large language models (LLMs) are being deployed at scale, yet we lack a systematic understanding of how the choice of backbone LLM affects agent security. The non-deterministic sequential nature of AI agents complicates…

Cryptography and Security · Computer Science 2026-02-25 Julia Bazinska , Max Mathys , Francesco Casucci , Mateo Rojas-Carulla , Xander Davies , Alexandra Souly , Niklas Pfister

Large Language Model-based Multi-Agent Systems (LLM-MAS) have revolutionized complex problem-solving capability by enabling sophisticated agent collaboration through message-based communications. While the communication framework is crucial…

Cryptography and Security · Computer Science 2025-06-03 Pengfei He , Yupin Lin , Shen Dong , Han Xu , Yue Xing , Hui Liu