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Multi-modal learning has shown exceptional performance in various tasks, especially in medical applications, where it integrates diverse medical information for comprehensive diagnostic evidence. However, there still are several challenges…

Machine Learning · Computer Science 2024-11-19 Lin Fan , Yafei Ou , Cenyang Zheng , Pengyu Dai , Tamotsu Kamishima , Masayuki Ikebe , Kenji Suzuki , Xun Gong

To obtain high-quality positron emission tomography (PET) scans while reducing radiation exposure to the human body, various approaches have been proposed to reconstruct standard-dose PET (SPET) images from low-dose PET (LPET) images. One…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Zeyu Han , Yuhan Wang , Luping Zhou , Peng Wang , Binyu Yan , Jiliu Zhou , Yan Wang , Dinggang Shen

Positron emission tomography (PET) is a well-established functional imaging technique for diagnosing brain disorders. However, PET's high costs and radiation exposure limit its widespread use. In contrast, magnetic resonance imaging (MRI)…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Yitong Li , Igor Yakushev , Dennis M. Hedderich , Christian Wachinger

Deep learning-based reconstruction of positron emission tomography(PET) data has gained increasing attention in recent years. While these methods achieve fast reconstruction,concerns remain regarding quantitative accuracy and the presence…

Low-count positron emission tomography (LCPET) imaging can reduce patients' exposure to radiation but often suffers from increased image noise and reduced lesion detectability, necessitating effective denoising techniques. Diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2025-03-24 Yinchi Zhou , Huidong Xie , Menghua Xia , Qiong Liu , Bo Zhou , Tianqi Chen , Jun Hou , Liang Guo , Xinyuan Zheng , Hanzhong Wang , Biao Li , Axel Rominger , Kuangyu Shi , Nicha C. Dvorneka , Chi Liu

Medical foundation models (MFMs) aim to learn universal representations from multimodal medical images that can generalize effectively to diverse downstream clinical tasks. However, most existing MFMs suffer from information ambiguity that…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Yihang Liu , Longzhen Yang , Jiaxiong Yang , Ying Wen , Lianghua He , Heng Tao Shen

Detail features of magnetic resonance images play a cru-cial role in accurate medical diagnosis and treatment, as they capture subtle changes that pose challenges for doc-tors when performing precise judgments. However, the widely utilized…

Computer Vision and Pattern Recognition · Computer Science 2024-05-10 Mengxiao Geng , Jiahao Zhu , Xiaolin Zhu , Qiqing Liu , Dong Liang , Qiegen Liu

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg

Positron emission tomography (PET) provides molecular biomarkers for Alzheimer's disease and related dementias (ADRD) and is increasingly used for diagnosis, staging, and clinical trial enrichment. However, its use is limited by cost,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-16 Junho Moon , Symac Kim , Haejun Chung , Ikbeom Jang

Ultra-low-dose positron emission tomography (PET) reconstruction holds significant potential for reducing patient radiation exposure and shortening examination times. However, it may also lead to increased noise and reduced imaging detail,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Mengxiao Geng , Ran Hong , Bingxuan Li , Qiegen Liu

Multi-modal medical imaging enables comprehensive diagnostics, yet current foundation models process 2D (e.g. X-ray) and 3D (e.g. CT) data with separate, dimensionality-specific architectures. We present MultiMedVision, a unified framework…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Frank Li , Bardia Khosravi , Mohammadreza Chavoshi , Young Seok Jeon , Theo Dapamede , Hari Trivedi , Janice Newsome , Judy Gichoya

The accurate segmentation of medical images is crucial for diagnosing and treating diseases. Recent studies demonstrate that vision transformer-based methods have significantly improved performance in medical image segmentation, primarily…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Wentao Wang , Xi Xiao , Mingjie Liu , Qing Tian , Xuanyao Huang , Qizhen Lan , Swalpa Kumar Roy , Tianyang Wang

The current methods for diagnosing Alzheimer Disease using Magnetic Resonance Imaging (MRI) have significant limitations. Many previous studies used 2D Transformers to analyze individual brain slices independently, potentially losing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Juan A. Castro-Silva , Maria N. Moreno Garcia , Diego H. Peluffo-Ordoñez

Imaging with multiple modalities or multiple channels is becoming increasingly important for our modern society. A key tool for understanding and early diagnosis of cancer and dementia is PET-MR, a combined positron emission tomography and…

Image and Video Processing · Electrical Eng. & Systems 2020-07-24 Matthias J. Ehrhardt

Early and accurate diagnosis and lesion localization of bone infections are crucial for clinical treatment. PET-CT integrates anatomical information from CT with metabolic information from PET, making it an important imaging modality for…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Zonglin Yang , Xiaolei Diao , Jishizhan Chen , Xiaozhuang Man , Wei Kong , Gen Wen , Pengfei Cheng , Daqian Shi

Large high-quality medical image datasets are difficult to acquire but necessary for many deep learning applications. For positron emission tomography (PET), reconstructed image quality is limited by inherent Poisson noise. We propose a…

Multimodal neuroimaging provides complementary insights for Alzheimer's disease diagnosis, yet clinical datasets frequently suffer from missing modalities. We propose ACADiff, a framework that synthesizes missing brain imaging modalities…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Rong Zhou , Houliang Zhou , Yao Su , Brian Y. Chen , Yu Zhang , Lifang He , Alzheimer's Disease Neuroimaging Initiative

In recent years, deep learning models have been applied to neuroimaging data for early diagnosis of Alzheimer's disease (AD). Structural magnetic resonance imaging (sMRI) and positron emission tomography (PET) images provide structural and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Yanteng Zhanga , Xiaohai He , Yi Hao Chan , Qizhi Teng , Jagath C. Rajapakse

18F-fluorodeoxyglucose (18F-FDG) Positron Emission Tomography (PET) imaging usually needs a full-dose radioactive tracer to obtain satisfactory diagnostic results, which raises concerns about the potential health risks of radiation…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Yu Fu , Shunjie Dong , Yi Liao , Le Xue , Yuanfan Xu , Feng Li , Qianqian Yang , Tianbai Yu , Mei Tian , Cheng Zhuo

Positron emission tomography (PET) combined with computed tomography (CT) imaging is routinely used in cancer diagnosis and prognosis by providing complementary information. Automatically segmenting tumors in PET/CT images can significantly…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Jinpeng Lu , Jingyun Chen , Linghan Cai , Songhan Jiang , Yongbing Zhang