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In computational biophysics, where molecular data is expanding rapidly and system complexity is increasing exponentially, large language models (LLMs) and agent-based systems are fundamentally reshaping the field. This perspective article…

The rapid advancement of Generative AI has catalyzed the emergence of autonomous AI agents, presenting unprecedented challenges for enterprise computing infrastructures. Current enterprise API architectures are predominantly designed for…

Software Engineering · Computer Science 2025-02-26 Vaibhav Tupe , Shrinath Thube

Despite the remarkable progress of large language models (LLMs), the capabilities of standalone LLMs have begun to plateau when tackling real-world, complex tasks that require interaction with external tools and dynamic environments.…

Large language model (LLM)-based computer-use agents represent a convergence of AI and OS capabilities, enabling natural language to control system- and application-level functions. However, due to LLMs' inherent uncertainty issues,…

Cryptography and Security · Computer Science 2026-01-15 Haochen Gong , Chenxiao Li , Rui Chang , Wenbo Shen

Large language models (LLMs) have become phenomenally surging, since 2018--two decades after introducing context-awareness into computing systems. Through taking into account the situations of ubiquitous devices, users and the societies,…

Computation and Language · Computer Science 2023-12-27 Haoyi Xiong , Jiang Bian , Sijia Yang , Xiaofei Zhang , Linghe Kong , Daqing Zhang

Large language model (LLM)-based agents that reason, plan, and act through tools, memory, and structured interaction are emerging as a promising paradigm for automating complex workflows. Recent systems such as OpenClaw and Claude Code…

Information Retrieval · Computer Science 2026-05-27 Yingli Zhou , Wang Shu , Yaodong Su , Wenchuan Du , Yixiang Fang , Xuemin Lin

We demonstrate that large language model (LLM) agents can autonomously perform tensor network simulations of quantum many-body systems, achieving approximately 90% success rate across representative benchmark tasks. Tensor network methods…

Quantum Physics · Physics 2026-01-16 Weitang Li , Jiajun Ren , Lixue Cheng , Cunxi Gong

In the midst of the growing integration of Artificial Intelligence (AI) into various aspects of our lives, agents are experiencing a resurgence. These autonomous programs that act on behalf of humans are neither new nor exclusive to the…

Artificial Intelligence · Computer Science 2024-12-24 Chirag Shah , Ryen W. White

Recent breakthroughs in Large Language Models (LLMs) have led to the emergence of agentic AI systems that extend beyond the capabilities of standalone models. By empowering LLMs to perceive external environments, integrate multimodal…

Artificial Intelligence · Computer Science 2025-03-24 Chengkai Huang , Junda Wu , Yu Xia , Zixu Yu , Ruhan Wang , Tong Yu , Ruiyi Zhang , Ryan A. Rossi , Branislav Kveton , Dongruo Zhou , Julian McAuley , Lina Yao

Computer use agents (CUA) are systems that automatically interact with graphical user interfaces (GUIs) to complete tasks. CUA have made significant progress with the advent of large vision-language models (VLMs). However, these agents…

Artificial Intelligence · Computer Science 2025-06-04 Man Luo , David Cobbley , Xin Su , Shachar Rosenman , Vasudev Lal , Shao-Yen Tseng , Phillip Howard

Digital agents capable of automating complex computer tasks have attracted considerable attention due to their immense potential to enhance human-computer interaction. However, existing agent methods exhibit deficiencies in their…

Artificial Intelligence · Computer Science 2024-10-25 Chengyou Jia , Minnan Luo , Zhuohang Dang , Qiushi Sun , Fangzhi Xu , Junlin Hu , Tianbao Xie , Zhiyong Wu

Large Language Model (LLM)-powered autonomous agents have demonstrated significant capabilities in virtual environments, yet their integration with the physical world remains narrowly confined to direct control interfaces. We present…

Multi-modal AI systems will likely become a ubiquitous presence in our everyday lives. A promising approach to making these systems more interactive is to embody them as agents within physical and virtual environments. At present, systems…

The advent of Large Language Models (LLMs) has significantly transformed tasks across Software Engineering. In the context of Business Process Management, LLMs are now being explored as tools to derive process models directly from textual…

Software Engineering · Computer Science 2026-05-01 Pedro-Aarón Hernández-Ávalos , Luciano García-Bañuelos

Large Language Model (LLM) web agents often struggle with long-horizon web navigation and web task completion in new websites, producing inefficient action sequences unless fine-tuned on environment-specific data. We show that…

Although large language models (LLMs) have revolutionized natural language processing capabilities, their practical implementation as autonomous multi-agent systems (MAS) for industrial problem-solving encounters persistent barriers.…

Computation and Language · Computer Science 2025-10-30 Hui Yi Leong , Yuheng Li , Yuqing Wu , Wenwen Ouyang , Wei Zhu , Jiechao Gao , Wei Han

Personalized learning represents a promising educational strategy within intelligent educational systems, aiming to enhance learners' practice efficiency. However, the discrepancy between offline metrics and online performance significantly…

Computers and Society · Computer Science 2026-05-29 Weibo Gao , Qi Liu , Linan Yue , Fangzhou Yao , Rui Lv , Zheng Zhang , Hao Wang , Zhenya Huang

The proliferation of large language models (LLMs) and their integration into multi-agent systems has paved the way for sophisticated automation in various domains. This paper introduces AutoGenesisAgent, a multi-agent system that…

Multiagent Systems · Computer Science 2024-04-29 Jeremy Harper

Traditionally, offline datasets have been used to evaluate task-oriented dialogue (TOD) models. These datasets lack context awareness, making them suboptimal benchmarks for conversational systems. In contrast, user-agents, which are…

Computation and Language · Computer Science 2024-11-18 Taaha Kazi , Ruiliang Lyu , Sizhe Zhou , Dilek Hakkani-Tur , Gokhan Tur

The emergence of AI agents powered by large language models (LLMs) marks a pivotal shift toward the Agentic Web, a new phase of the internet defined by autonomous, goal-driven interactions. In this paradigm, agents interact directly with…