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The potential of Multimodal Large Language Models (MLLMs) in domain of medical imaging raise the demands of systematic and rigorous evaluation frameworks that are aligned with the real-world medical imaging practice. Existing practices that…

Computation and Language · Computer Science 2026-04-16 Zhijie Bao , Fangke Chen , Licheng Bao , Chenhui Zhang , Wei Chen , Jiajie Peng , Zhongyu Wei

The clinical adoption of artificial intelligence (AI) in medical imaging requires models that are both diagnostically accurate and interpretable to clinicians. While current multimodal biomedical foundation models prioritize performance,…

Concept Bottleneck Models (CBM) are inherently interpretable models that factor model decisions into human-readable concepts. They allow people to easily understand why a model is failing, a critical feature for high-stakes applications.…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Yue Yang , Artemis Panagopoulou , Shenghao Zhou , Daniel Jin , Chris Callison-Burch , Mark Yatskar

Concept Bottleneck Models (CBMs) ground image classification on human-understandable concepts to allow for interpretable model decisions. Crucially, the CBM design inherently allows for human interventions, in which expert users are given…

Machine Learning · Computer Science 2024-08-07 Nishad Singhi , Jae Myung Kim , Karsten Roth , Zeynep Akata

Modern deep neural networks have now reached human-level performance across a variety of tasks. However, unlike humans they lack the ability to explain their decisions by showing where and telling what concepts guided them. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Itay Benou , Tammy Riklin-Raviv

Concept Bottleneck Models (CBMs) are machine learning models that improve interpretability by grounding their predictions on human-understandable concepts, allowing for targeted interventions in their decision-making process. However, when…

Explainable AI (XAI) is crucial for building transparent and trustworthy machine learning systems, especially in high-stakes domains. Concept Bottleneck Models (CBMs) have emerged as a promising ante-hoc approach that provides…

Artificial Intelligence · Computer Science 2026-01-21 Hanwei Zhang , Luo Cheng , Rui Wen , Yang Zhang , Lijun Zhang , Holger Hermanns

Enhancing model interpretability can address spurious correlations by revealing how models draw their predictions. Concept Bottleneck Models (CBMs) can provide a principled way of disclosing and guiding model behaviors through…

Machine Learning · Computer Science 2024-07-15 Jeeyung Kim , Ze Wang , Qiang Qiu

Black-box deep neural networks excel in text classification, yet their application in high-stakes domains is hindered by their lack of interpretability. To address this, we propose Text Bottleneck Models (TBM), an intrinsically…

Computation and Language · Computer Science 2024-04-04 Josh Magnus Ludan , Qing Lyu , Yue Yang , Liam Dugan , Mark Yatskar , Chris Callison-Burch

Explaining Deep Learning models is becoming increasingly important in the face of daily emerging multimodal models, particularly in safety-critical domains like medical imaging. However, the lack of detailed investigations into the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 Anees Ur Rehman Hashmi , Dwarikanath Mahapatra , Mohammad Yaqub

Radiology Report Generation (RRG) through Vision-Language Models (VLMs) promises to reduce documentation burden, improve reporting consistency, and accelerate clinical workflows. However, their clinical adoption remains limited by the lack…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Marco Salmè , Federico Siciliano , Fabrizio Silvestri , Paolo Soda , Rosa Sicilia , Valerio Guarrasi

The opaque nature of Large Language Models (LLMs) has led to significant research efforts aimed at enhancing their interpretability, primarily through post-hoc methods. More recent in-hoc approaches, such as Concept Bottleneck Models…

Machine Learning · Computer Science 2025-02-20 Or Raphael Bidusa , Shaul Markovitch

Concept Bottleneck Models (CBMs) predict through human-interpretable concepts, but they typically output point concept probabilities that conflate epistemic uncertainty (reducible model underspecification) with aleatoric uncertainty…

Artificial Intelligence · Computer Science 2026-04-28 Tanmoy Mukherjee , Thomas Bailleux , Pierre Marquis , Zied Bouraoui

Concept bottleneck models (CBMs) are interpretable neural networks that first predict labels for human-interpretable concepts relevant to the prediction task, and then predict the final label based on the concept label predictions. We…

Machine Learning · Computer Science 2023-04-28 Kushal Chauhan , Rishabh Tiwari , Jan Freyberg , Pradeep Shenoy , Krishnamurthy Dvijotham

Concept-based learning enhances prediction accuracy and interpretability by leveraging high-level, human-understandable concepts. However, existing CBL frameworks do not address survival analysis tasks, which involve predicting event times…

Machine Learning · Computer Science 2025-02-11 Stanislav R. Kirpichenko , Lev V. Utkin , Andrei V. Konstantinov , Natalya M. Verbova

MLLMs MLLMs are beginning to appear in clinical workflows, but their ability to perform complex medical reasoning remains unclear. We present Med-CMR, a fine-grained Medical Complex Multimodal Reasoning benchmark. Med-CMR distinguishes from…

Deep learning methods are highly accurate, yet their opaque decision process prevents them from earning full human trust. Concept-based models aim to address this issue by learning tasks based on a set of human-understandable concepts.…

Concept bottleneck models (CBMs) are inherently interpretable and intervenable neural network models, which explain their final label prediction by the intermediate prediction of high-level semantic concepts. However, they require target…

Machine Learning · Computer Science 2026-04-06 Shin'ya Yamaguchi , Kosuke Nishida , Daiki Chijiwa , Yasutoshi Ida

MLLMs (Multimodal Large Language Models) have showcased remarkable capabilities, but their performance in high-stakes, domain-specific scenarios like surgical settings, remains largely under-explored. To address this gap, we develop…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Gui Wang , Yang Wennuo , Xusen Ma , Zehao Zhong , Zhuoru Wu , Ende Wu , Rong Qu , Wooi Ping Cheah , Jianfeng Ren , Linlin Shen

Concept Bottleneck Models (CBMs) try to make the decision-making process transparent by exploring an intermediate concept space between the input image and the output prediction. Existing CBMs just learn coarse-grained relations between the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Yan Xie , Zequn Zeng , Hao Zhang , Yucheng Ding , Yi Wang , Zhengjue Wang , Bo Chen , Hongwei Liu
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