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Although the combined treatment of surgery, radiotherapy, chemotherapy, and emerging target therapy has significantly improved the outcomes of patients with head and neck cancer, distant metastasis remains the leading cause of treatment…

Quantitative Methods · Quantitative Biology 2025-12-02 Nuo Tong , Changhao Liu , Zizhao Tang , Feifan Sun , Yingping Li , Shuiping Gou , Mei Shi

Mitotic activity is an important feature for grading several cancer types. Counting mitotic figures (MFs) is a time-consuming, laborious task prone to inter-observer variation. Inaccurate recognition of MFs can lead to incorrect grading and…

Brain tumors are collections of abnormal cells that can develop into masses or clusters. Because they have the potential to infiltrate other tissues, they pose a risk to the patient. The main imaging technique used, MRI, may be able to…

Image and Video Processing · Electrical Eng. & Systems 2023-09-22 Razia Sultana Misu

Multimodal machine learning integrating histopathology and molecular data shows promise for cancer prognostication. We systematically reviewed studies combining whole slide images (WSIs) and high-throughput omics to predict overall…

Quantitative Methods · Quantitative Biology 2025-07-30 Charlotte Jennings , Andrew Broad , Lucy Godson , Emily Clarke , David Westhead , Darren Treanor

Detecting cancers at early stages can dramatically reduce mortality rates. Therefore, practical cancer screening at the population level is needed. Here, we develop a comprehensive detection system to classify all common cancer types. By…

Molecular Networks · Quantitative Biology 2021-03-30 Anyou Wang , Rong Hai , Paul J Rider , Qianchuan He

Melanoma is not the most common form of skin cancer, but it is the most deadly. Currently, the disease is diagnosed by expert dermatologists, which is costly and requires timely access to medical treatment. Recent advances in deep learning…

Computer Vision and Pattern Recognition · Computer Science 2020-11-19 Emma Rocheteau , Doyoon Kim

Recent studies have shown promising results in using Deep Learning to detect malignancy in whole slide imaging. However, they were limited to just predicting positive or negative finding for a specific neoplasm. We attempted to use Deep…

Computer Vision and Pattern Recognition · Computer Science 2018-11-08 Hanadi El Achi , Tatiana Belousova , Lei Chen , Amer Wahed , Iris Wang , Zhihong Hu , Zeyad Kanaan , Adan Rios , Andy N. D. Nguyen

Skin cancer is by far in top-3 of the world's most common cancer. Among different skin cancer types, melanoma is particularly dangerous because of its ability to metastasize. Early detection is the key to success in skin cancer treatment.…

Artificial Intelligence · Computer Science 2020-09-15 Duyen N. T. Le , Hieu X. Le , Lua T. Ngo , Hoan T. Ngo

The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep learning algorithm that can accurately detect breast cancer…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Li Shen , Laurie R. Margolies , Joseph H. Rothstein , Eugene Fluder , Russell B. McBride , Weiva Sieh

Renal Cell Carcinoma is typically asymptomatic at the early stages for many patients. This leads to a late diagnosis of the tumor, where the curability likelihood is lower, and makes the mortality rate of Renal Cell Carcinoma high, with…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Mohamad Mohamad , Francesco Ponzio , Santa Di Cataldo , Damien Ambrosetti , Xavier Descombes

Optical transmission spectroscopy is one method to understand brain tissue structural properties from brain tissue biopsy samples, yet manual interpretation is resource intensive and prone to inter observer variability. Deep convolutional…

Medical Physics · Physics 2025-05-20 Mohnish Sao , Mousa Alrubayan , Prabhakar Pradhan

Background: Breast ultrasound is prominently used in diagnosing breast tumors. At present, many automatic systems based on deep learning have been developed to help radiologists in diagnosis. However, training such systems remains…

Computer Vision and Pattern Recognition · Computer Science 2024-08-21 Yunxin Tang , Siyuan Tang , Jian Zhang , Hao Chen

Brain tumors pose a significant threat to human life, therefore it is very much necessary to detect them accurately in the early stages for better diagnosis and treatment. Brain tumors can be detected by the radiologist manually from the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Sayan Das , Arghadip Biswas

Accurate prognosis of a tumor can help doctors provide a proper course of treatment and, therefore, save the lives of many. Traditional machine learning algorithms have been eminently useful in crafting prognostic models in the last few…

Image and Video Processing · Electrical Eng. & Systems 2022-02-28 Numan Saeed , Roba Al Majzoub , Ikboljon Sobirov , Mohammad Yaqub

This research introduces a sophisticated transfer learning model based on Google's MobileNetV2 for breast cancer tumor classification into normal, benign, and malignant categories, utilizing a dataset of 1576 ultrasound images (265 normal,…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Aaditya Surya , Aditya Shah , Jarnell Kabore , Subash Sasikumar

Purpose; The purpose of this study is to classify glial tumors into grade II, III and IV categories noninvasively by application of machine learning to multi-modal MRI features in comparison with volumetric analysis. Methods; We…

Image and Video Processing · Electrical Eng. & Systems 2022-08-16 Sevcan Turk , Kaya Oguz , Mehmet Orman , Emre Caliskan , Yesim Ertan , Erkin Ozgiray , Taner Akalin , Ashok Srinivasan , Omer Kitis

Colorectal cancer (CRC) grading is a critical prognostic factor but remains hampered by inter-observer variability and the privacy constraints of multi-institutional data sharing. While deep learning offers a path to automation, centralized…

Brain tumor is one of the leading causes of cancer-related death globally among children and adults. Precise classification of brain tumor grade (low-grade and high-grade glioma) at early stage plays a key role in successful prognosis and…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Ruqian Hao , Khashayar Namdar , Lin Liu , Farzad Khalvati

The prediction of pancreatic ductal adenocarcinoma therapy response is a clinically challenging and important task in this high-mortality tumour entity. The training of neural networks able to tackle this challenge is impeded by a lack of…

Image and Video Processing · Electrical Eng. & Systems 2023-03-31 Alexander Ziller , Ayhan Can Erdur , Friederike Jungmann , Daniel Rueckert , Rickmer Braren , Georgios Kaissis

We propose a method to accurately obtain the ratio of tumor cells over an entire histological slide. We use deep fully convolutional neural network models trained to detect and classify cells on images of H&E-stained tissue sections.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Eric Cosatto , Kyle Gerard , Hans-Peter Graf , Maki Ogura , Tomoharu Kiyuna , Kanako C. Hatanaka , Yoshihiro Matsuno , Yutaka Hatanaka
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