Related papers: Fluid-Solid Pattern Formation and Strain Localisat…
Multicellular rosettes are observed in different situations such as morphogenesis, wound healing, and cancer progression. While some molecular insights have been gained to explain the presence of these assemblies of five or more cells…
Many soft materials, including foams, dense emulsions, micro gel bead suspensions, star polymers, dense packing of surfactant onion micelles, and textured morphologies of liquid crystals, share the basic "glassy" features of structural…
Strain in sheared dense granular material is often localized in a narrow region called shear band. Recent experiments in a modified Couette cell provided localized shear flow in the bulk away from the confining walls. The non-trivial shape…
It has recently been argued that steady-state vorticity bands cannot arise in shear thickening suspensions, because the normal stress imbalance across the interface between the bands will set up particle migrations. In this Letter, we…
One prototypical instability in granular flows is the shear-banding instability, in which a uniform granular shear flow breaks into alternating bands of dense and dilute clusters of particles having low and high shear (shear stress or shear…
Strain in granular materials in quasistatic conditions under varying stress originate in (I) contact deformation and (II) rearrangements of the contact network. Depending on sample history and applied load, either mechanism might dominate.…
Pattern formation from homogeneity is well-studied, but less is known concerning symmetry-breaking instabilities in heterogeneous media. It is nontrivial to separate observed spatial patterning due to inherent spatial heterogeneity from…
During development and under normal physiological conditions, biological tissues are continuously subjected to substantial mechanical stresses. In response to large deformations cells in a tissue must undergo multicellular rearrangements in…
Spatial patterns arising spontaneously due to internal processes are ubiquitous in nature, varying from regular patterns of dryland vegetation to complex structures of bacterial colonies. Many of these patterns can be explained in the…
We study theoretically the shapes of biological tubes affected by various pathologies. When epithelial cells grow at an uncontrolled rate, the negative tension produced by their division provokes a buckling instability. Several shapes are…
The spontaneous emergence of heterogeneous dislocation patterns is a conspicuous feature of plastic deformation and strain hardening of crystalline solids. Despite long-standing efforts in the materials science and physics of defect…
Spontaneous pattern formation in homogeneous systems is ubiquitous in nature. Although Turing demonstrated that spatial patterns can emerge in reaction-diffusion (RD) systems when the homogeneous state becomes linearly unstable, it remains…
Confirming Turing's theory of morphogens in developmental processes is challenging, and synthetic biology has opened new avenues for testing Turing's predictions. Synthetic mammalian pattern formation has been recently achieved through a…
Connecting cell behavior to tissue shape and mechanics is a key challenge in the physics of morphogenesis. Cytoskeletal turnover precludes a fixed reference state, and tensions are actively generated independently of strain; so conventional…
Biological soft tissues exhibit elastic properties which can be dramatically different from rubber-type materials (elastomers). To gain a better understanding of the role of constitutive relationships in determining material responses under…
The conditions under which biological cells switch from a static to a motile state are fundamental to the understanding of many healthy and pathological processes. In this paper, we show that even in the presence of a fully symmetric…
Recent 3D organ reconstitution studies show that a group of stem cells can establish a body axis and acquire different fates in a spatially organized manner. How such symmetry breaking happens in the absence of external spatial cues, and…
The biopolymers actin and microtubules are often in an ongoing assembling/disassembling state far from thermal equilibrium. Above a critical density this leads to spatially periodic patterns, as shown by a scaling argument and in terms of a…
The term "solid-state turbulence" may sound like an oxymoron, but in fact it is not. In this article we demonstrate that solid-state turbulence may emerge owing to a defining property of the solid state: the ability of a solid to retain its…
Morphogenesis involves complex shape changes of biological tissues. Yet, tissue shape changes depend on tissue rheology, which in turn arises from the interplay of large numbers of cells. Here, we link cell- and tissue-scale mechanics by…