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Medical image segmentation remains challenging due to the high cost of pixel-level annotations for training. In the context of weak supervision, clinician gaze data captures regions of diagnostic interest; however, its sparsity limits its…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Jingkun Chen , Haoran Duan , Xiao Zhang , Boyan Gao , Vicente Grau , Jungong Han

Weakly supervised nuclei segmentation is a critical problem for pathological image analysis and greatly benefits the community due to the significant reduction of labeling cost. Adopting point annotations, previous methods mostly rely on…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Weizhen Liu , Qian He , Xuming He

Supervised deep learning for semantic segmentation has achieved excellent results in accurately identifying anatomical and pathological structures in medical images. However, it often requires large annotated training datasets, which limits…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Luca Ciampi , Gabriele Lagani , Giuseppe Amato , Fabrizio Falchi

Generating realistic tissue images with annotations is a challenging task that is important in many computational histopathology applications. Synthetically generated images and annotations are valuable for training and evaluating…

Image and Video Processing · Electrical Eng. & Systems 2024-04-08 Srijay Deshpande , Fayyaz Minhas , Nasir Rajpoot

With the rapid advancement of deep learning, computational pathology has made significant progress in cancer diagnosis and subtyping. Tissue segmentation is a core challenge, essential for prognosis and treatment decisions. Weakly…

Computer Vision and Pattern Recognition · Computer Science 2025-01-08 Hongyi Wu , Hong Zhang

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Segmenting tumors in histological images is vital for cancer diagnosis. While fully supervised models excel with pixel-level annotations, creating such annotations is labor-intensive and costly. Accurate histopathology image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Yinsheng He , Xingyu Li , Roger J. Zemp

Accurate segmentation of Optical Coherence Tomography (OCT) images is crucial for diagnosing and monitoring retinal diseases. However, the labor-intensive nature of pixel-level annotation limits the scalability of supervised learning for…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Jiaqi Yang , Nitish Mehta , Xiaoling Hu , Chao Chen , Chia-Ling Tsai

Deep convolutional neural networks have shown outstanding performance in medical image segmentation tasks. The usual problem when training supervised deep learning methods is the lack of labeled data which is time-consuming and costly to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-04 Suman Sedai , Bhavna Antony , Ravneet Rai , Katie Jones , Hiroshi Ishikawa , Joel Schuman , Wollstein Gadi , Rahil Garnavi

Semi-supervised semantic segmentation aims to utilize limited labeled images and abundant unlabeled images to achieve label-efficient learning, wherein the weak-to-strong consistency regularization framework, popularized by FixMatch, is…

Computer Vision and Pattern Recognition · Computer Science 2023-12-15 Wentao Pan , Zhe Xu , Jiangpeng Yan , Zihan Wu , Raymond Kai-yu Tong , Xiu Li , Jianhua Yao

Developing an AI-assisted gland segmentation method from histology images is critical for automatic cancer diagnosis and prognosis; however, the high cost of pixel-level annotations hinders its applications to broader diseases. Existing…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Yi Li , Yiduo Yu , Yiwen Zou , Tianqi Xiang , Xiaomeng Li

Image segmentation is a fundamental task in the field of imaging and vision. Supervised deep learning for segmentation has achieved unparalleled success when sufficient training data with annotated labels are available. However, annotation…

Image and Video Processing · Electrical Eng. & Systems 2023-04-10 Hongrun Zhang , Liam Burrows , Yanda Meng , Declan Sculthorpe , Abhik Mukherjee , Sarah E Coupland , Ke Chen , Yalin Zheng

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

Learning semantic segmentation models under image-level supervision is far more challenging than under fully supervised setting. Without knowing the exact pixel-label correspondence, most weakly-supervised methods rely on external models to…

Computer Vision and Pattern Recognition · Computer Science 2018-10-17 Zi-Yi Ke , Chiou-Ting Hsu

Eye gaze that reveals human observational patterns has increasingly been incorporated into solutions for vision tasks. Despite recent explorations on leveraging gaze to aid deep networks, few studies exploit gaze as an efficient annotation…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Yuan Zhong , Chenhui Tang , Yumeng Yang , Ruoxi Qi , Kang Zhou , Yuqi Gong , Pheng Ann Heng , Janet H. Hsiao , Qi Dou

This work proposes a novel approach beyond supervised learning for effective pathological image analysis, addressing the challenge of limited robust labeled data. Pathological diagnosis of diseases like cancer has conventionally relied on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Joonhyeon Song , Seohwan Yun , Seongho Yoon , Joohyeok Kim , Sangmin Lee

Throughout the world, breast cancer is one of the leading causes of female death. Recently, deep learning methods are developed to automatically grade breast cancer of histological slides. However, the performance of existing deep learning…

Computer Vision and Pattern Recognition · Computer Science 2022-03-09 Yanyuet Man , Xiangyun Ding , Xingcheng Yao , Han Bao

Segmentation using deep learning has shown promising directions in medical imaging as it aids in the analysis and diagnosis of diseases. Nevertheless, a main drawback of deep models is that they require a large amount of pixel-level labels,…

Computer Vision and Pattern Recognition · Computer Science 2020-04-08 Sukesh Adiga , Jose Dolz , Herve Lombaert

Semi- and weakly-supervised learning have recently attracted considerable attention in the object detection literature since they can alleviate the cost of annotation needed to successfully train deep learning models. State-of-art…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Akhil Meethal , Marco Pedersoli , Zhongwen Zhu , Francisco Perdigon Romero , Eric Granger

Accurate gland segmentation in histopathology images is essential for cancer diagnosis and prognosis. However, significant variability in Hematoxylin and Eosin (H&E) staining and tissue morphology, combined with limited annotated data,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Ha-Hieu Pham , Nguyen Lan Vi Vu , Thanh-Huy Nguyen , Ulas Bagci , Min Xu , Trung-Nghia Le , Huy-Hieu Pham