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Objective: While recent advances in text-conditioned generative models have enabled the synthesis of realistic medical images, progress has been largely confined to 2D modalities such as chest X-rays. Extending text-to-image generation to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Daniele Molino , Camillo Maria Caruso , Filippo Ruffini , Paolo Soda , Valerio Guarrasi

This paper introduces an innovative methodology for producing high-quality 3D lung CT images guided by textual information. While diffusion-based generative models are increasingly used in medical imaging, current state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Yanwu Xu , Li Sun , Wei Peng , Shuyue Jia , Katelyn Morrison , Adam Perer , Afrooz Zandifar , Shyam Visweswaran , Motahhare Eslami , Kayhan Batmanghelich

Generative vision-language models can produce fluent medical image captions but remain prone to hallucination, over-specific diagnostic claims, and factual inconsistency-serious issues in pathology. We investigate retrieval-guided…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Md. Enamul Hoq , Wataru Uegami , Saghir Alfasly , Ghazal Alabtah , Sahar Rahimi Malakshan , Armita Kazemi , Alex T. Schmitgen , Fred Prior , H. R. Tizhoosh

Generating 3D CT volumes from descriptive free-text inputs presents a transformative opportunity in diagnostics and research. In this paper, we introduce Text2CT, a novel approach for synthesizing 3D CT volumes from textual descriptions…

Image and Video Processing · Electrical Eng. & Systems 2025-05-09 Pengfei Guo , Can Zhao , Dong Yang , Yufan He , Vishwesh Nath , Ziyue Xu , Pedro R. A. S. Bassi , Zongwei Zhou , Benjamin D. Simon , Stephanie Anne Harmon , Baris Turkbey , Daguang Xu

GenerateCT, the first approach to generating 3D medical imaging conditioned on free-form medical text prompts, incorporates a text encoder and three key components: a novel causal vision transformer for encoding 3D CT volumes, a text-image…

The recently emerging conditional diffusion models seem promising for mitigating the labor and expenses in building large 3D medical imaging datasets. However, previous studies on 3D CT generation primarily focus on specific organs…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Linrui Dai , Rongzhao Zhang , Yongrui Yu , Xiaofan Zhang

Medical image synthesis is crucial for alleviating data scarcity and privacy constraints. However, fine-tuning general text-to-image (T2I) models remains challenging, mainly due to the significant modality gap between complex visual details…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Xin Huang , Junjie Liang , Qingshan Hou , Peng Cao , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane

Recent advances in synthetic imaging open up opportunities for obtaining additional data in the field of surgical imaging. This data can provide reliable supplements supporting surgical applications and decision-making through computer…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Simeon Allmendinger , Patrick Hemmer , Moritz Queisner , Igor Sauer , Leopold Müller , Johannes Jakubik , Michael Vössing , Niklas Kühl

Retrieval augmented generation mitigates limitations of large language models in factual consistency and knowledge updating by introducing external knowledge. However, practical applications still suffer from semantic misalignment between…

Computation and Language · Computer Science 2026-03-06 Xin Chen , Saili Uday Gadgil , Jiarong Qiu

We develop an approach for text-to-image generation that embraces additional retrieval images, driven by a combination of implicit visual guidance loss and generative objectives. Unlike most existing text-to-image generation methods which…

Computer Vision and Pattern Recognition · Computer Science 2022-08-19 Xin Yuan , Zhe Lin , Jason Kuen , Jianming Zhang , John Collomosse

Large language models record impressive performance on many natural language processing tasks. However, their knowledge capacity is limited to the pretraining corpus. Retrieval augmentation offers an effective solution by retrieving context…

Computation and Language · Computer Science 2023-11-22 Sai Munikoti , Anurag Acharya , Sridevi Wagle , Sameera Horawalavithana

Automated radiology report generation from 3D CT volumes often suffers from incomplete pathology coverage. We provide empirical evidence that this limitation stems from a representational bottleneck: contrastive 3D CT embeddings encode…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Renjie Liang , Yiling Ma , Yang Xing , Zhengkang Fan , Jinqian Pan , Chengkun Sun , Li Li , Kuang Gong , Jie Xu

Novel architectures have recently improved generative image synthesis leading to excellent visual quality in various tasks. Of particular note is the field of ``AI-Art'', which has seen unprecedented growth with the emergence of powerful…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Robin Rombach , Andreas Blattmann , Björn Ommer

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

Text-to-image synthesis has achieved high-quality results with recent advances in diffusion models. However, text input alone has high spatial ambiguity and limited user controllability. Most existing methods allow spatial control through…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Yuki Endo

Multimodal models trained on large natural image-text pair datasets have exhibited astounding abilities in generating high-quality images. Medical imaging data is fundamentally different to natural images, and the language used to…

Recent text-to-image generation favors various forms of spatial conditions, e.g., masks, bounding boxes, and key points. However, the majority of the prior art requires form-specific annotations to fine-tune the original model, leading to…

Computer Vision and Pattern Recognition · Computer Science 2025-01-03 Z. Zhang , B. Liu , J. Bao , L. Chen , S. Zhu , J. Yu

This paper addresses the performance bottlenecks of existing text-driven image generation methods in terms of semantic alignment accuracy and structural consistency. A high-fidelity image generation method is proposed by integrating…

Computer Vision and Pattern Recognition · Computer Science 2025-08-15 Danyi Gao

Deep generative models have significantly advanced medical imaging analysis by enhancing dataset size and quality. Beyond mere data augmentation, our research in this paper highlights an additional, significant capacity of deep generative…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Xiaodan Xing , Junzhi Ning , Yang Nan , Guang Yang

The use of synthetic images in medical imaging Artificial Intelligence (AI) solutions has been shown to be beneficial in addressing the limited availability of diverse, unbiased, and representative data. Despite the extensive use of…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Elay Dahan , Hedda Cohen Indelman , Angeles M. Perez-Agosto , Carmit Shiran , Gopal Avinash , Doron Shaked , Nati Daniel
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