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Physics-Informed Machine Learning (PIML) offers a powerful paradigm of integrating data with physical laws to address important scientific problems, such as parameter estimation, inferring hidden physics, equation discovery, and state…

Computational Engineering, Finance, and Science · Computer Science 2025-10-31 Letian Yi , Siyuan Yang , Ying Cui , Zhilu Lai

Physics-Informed Machine Learning (PIML) has gained momentum in the last 5 years with scientists and researchers aiming to utilize the benefits afforded by advances in machine learning, particularly in deep learning. With large scientific…

Computational Physics · Physics 2021-05-26 Samuel J. Raymond , David B. Camarillo

The convergence of statistical learning and molecular physics is transforming our approach to modeling biomolecular systems. Physics-informed machine learning (PIML) offers a systematic framework that integrates data-driven inference with…

Biomolecules · Quantitative Biology 2025-11-11 Aaryesh Deshpande

Physics-informed machine learning (PIML) integrates partial differential equations (PDEs) into machine learning models to solve inverse problems, such as estimating coefficient functions (e.g., the Hamiltonian function) that characterize…

Computational Physics · Physics 2025-11-07 Yoh-ichi Mototake , Makoto Sasaki

Recent advances of data-driven machine learning have revolutionized fields like computer vision, reinforcement learning, and many scientific and engineering domains. In many real-world and scientific problems, systems that generate data are…

Machine Learning · Computer Science 2023-03-08 Zhongkai Hao , Songming Liu , Yichi Zhang , Chengyang Ying , Yao Feng , Hang Su , Jun Zhu

Physics-informed machine learning (PIML) as a means of solving partial differential equations (PDE) has garnered much attention in the Computational Science and Engineering (CS&E) world. This topic encompasses a broad array of methods and…

Machine Learning · Computer Science 2024-09-05 Michael Penwarden , Houman Owhadi , Robert M. Kirby

Physics-Informed Machine Learning (PIML) has successfully integrated mechanistic understanding into machine learning, particularly in domains governed by well-known physical laws. This success has motivated efforts to apply PIML to biology,…

Machine Learning · Computer Science 2025-10-30 Julien Martinelli

Optimization is central to both modern machine learning (ML) and scientific machine learning (SciML), yet the structure of the underlying optimization problems differs substantially across these domains. Classical ML typically relies on…

Numerical Analysis · Mathematics 2026-01-16 Alena Kopaničáková , Elisa Riccietti

We present a physics-informed machine-learning (PIML) approach for the approximation of slow invariant manifolds (SIMs) of singularly perturbed systems, providing functionals in an explicit form that facilitate the construction and…

Dynamical Systems · Mathematics 2024-11-05 Dimitrios G. Patsatzis , Gianluca Fabiani , Lucia Russo , Constantinos Siettos

A primary challenge of physics-informed machine learning (PIML) is its generalization beyond the training domain, especially when dealing with complex physical problems represented by partial differential equations (PDEs). This paper aims…

Machine Learning · Computer Science 2023-12-19 Taniya Kapoor , Abhishek Chandra , Daniel M. Tartakovsky , Hongrui Wang , Alfredo Nunez , Rolf Dollevoet

Manifold optimization is ubiquitous in computational and applied mathematics, statistics, engineering, machine learning, physics, chemistry and etc. One of the main challenges usually is the non-convexity of the manifold constraints. By…

Optimization and Control · Mathematics 2019-06-14 Jiang Hu , Xin Liu , Zaiwen Wen , Yaxiang Yuan

Reinforcement learning (RL) has achieved strong performance in robotic control; however, state-of-the-art policy learning methods, such as actor-critic methods, still suffer from high sample complexity and often produce physically…

Robotics · Computer Science 2026-03-24 Namai Chandra , Liu Mohan , Zhihao Gu , Lin Wang

Path planning is usually solved by addressing either the (high-level) route planning problem (waypoint sequencing to achieve the final goal) or the (low-level) path planning problem (trajectory prediction between two waypoints avoiding…

Topology optimization is used for the design of high-performance structures but remains fundamentally limited by its iterative nature, requiring repeated finite element analyses that prevent real-time deployment and large-scale design…

Computational Engineering, Finance, and Science · Computer Science 2026-04-07 Aaron Lutheran , Srijan Das , Alireza Tabarraei

Algorithms proposed for solving high-dimensional optimization problems with no derivative information frequently encounter the "curse of dimensionality," becoming ineffective as the dimension of the parameter space grows. One feature of a…

Optimization and Control · Mathematics 2020-04-28 Dmitry Pozharskiy , Noah J. Wichrowski , Andrew B. Duncan , Grigorios A. Pavliotis , Ioannis G. Kevrekidis

We are delighted to see the recent development of physics-informed extreme learning machine (PIELM) for its higher computational efficiency and accuracy compared to other physics-informed machine learning (PIML) paradigms. Since a…

Machine Learning · Computer Science 2025-11-04 He Yang , Fei Ren , Francesco Calabro , Hai-Sui Yu , Xiaohui Chen , Pei-Zhi Zhuang

Inspired by applications in optimal control of semilinear elliptic partial differential equations and physics-integrated imaging, differential equation constrained optimization problems with constituents that are only accessible through…

Optimization and Control · Mathematics 2020-08-26 Guozhi Dong , Michael Hintermueller , Kostas Papafitsoros

As the size and ubiquity of artificial intelligence and computational machine learning (ML) models grow, their energy consumption for training and use is rapidly becoming economically and environmentally unsustainable. Neuromorphic…

Disordered Systems and Neural Networks · Physics 2023-10-17 Menachem Stern , Sam Dillavou , Dinesh Jayaraman , Douglas J. Durian , Andrea J. Liu

Designing physical artifacts that serve a purpose - such as tools and other functional structures - is central to engineering as well as everyday human behavior. Though automating design has tremendous promise, general-purpose methods do…

Polymer simulation with both accuracy and efficiency is a challenging task. Machine learning (ML) forcefields have been developed to achieve both the accuracy of ab initio methods and the efficiency of empirical force fields. However,…

Machine Learning · Computer Science 2023-09-04 Rui Feng , Huan Tran , Aubrey Toland , Binghong Chen , Qi Zhu , Rampi Ramprasad , Chao Zhang
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