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Conventional biomedical research is increasingly labor-intensive due to the exponential growth of scientific literature and datasets. Artificial intelligence (AI), particularly Large Language Models (LLMs), has the potential to…

Multiagent Systems · Computer Science 2025-07-08 Yi Luo , Linghang Shi , Yihao Li , Aobo Zhuang , Yeyun Gong , Ling Liu , Chen Lin

Complex agentic AI systems, powered by a coordinated ensemble of Large Language Models (LLMs), tool and memory modules, have demonstrated remarkable capabilities on intricate, multi-turn tasks. However, this success is shadowed by…

Computation and Language · Computer Science 2026-01-07 Guibin Zhang , Haiyang Yu , Kaiming Yang , Bingli Wu , Fei Huang , Yongbin Li , Shuicheng Yan

Large language models hold promise as scientific assistants, yet existing agents either rely solely on algorithm evolution or on deep research in isolation, both of which face critical limitations. Pure algorithm evolution, as in…

Artificial Intelligence · Computer Science 2025-10-08 Gang Liu , Yihan Zhu , Jie Chen , Meng Jiang

LLM-empowered multi-agent systems offer new potential to accelerate scientific discovery by generating novel research ideas. However, existing methods typically coordinate agents through temporary texts, such as drafts or chat logs; it is…

Multiagent Systems · Computer Science 2026-05-07 Jiangwen Dong , Bo Li , Wanyu Lin

Experience-driven self-evolving agents aim to overcome the static nature of large language models by distilling reusable experience from past interactions, thus enabling adaptation to novel tasks at deployment time. This process places…

Artificial Intelligence · Computer Science 2026-05-12 Zhiyuan Fan , Wenwei Jin , Feng Zhang , Bin Li , Yihong Dong , Yao Hu , Jiawei Li

Scientific discovery is often slowed by the manual development of computational tools needed to analyze complex experimental data. Building such tools is costly and time-consuming because scientists must iteratively review literature, test…

Artificial Intelligence · Computer Science 2026-05-19 Alistair Turcan , Kexin Huang , Lei Li , Martin Jinye Zhang

Computing has long served as a cornerstone of scientific discovery. Recently, a paradigm shift has emerged with the rise of large language models (LLMs), introducing autonomous systems, referred to as agents, that accelerate discovery…

The advancement of artificial intelligence toward agentic science is currently bottlenecked by the challenge of ultra-long-horizon autonomy, the ability to sustain strategic coherence and iterative correction over experimental cycles…

Artificial Intelligence · Computer Science 2026-03-26 Xinyu Zhu , Yuzhu Cai , Zexi Liu , Bingyang Zheng , Cheng Wang , Rui Ye , Yuzhi Zhang , Linfeng Zhang , Weinan E , Siheng Chen , Yanfeng Wang

Automatic research with Large Language Models (LLMs) is rapidly gaining importance, driving the development of increasingly complex workflows involving multi-agent systems, planning, tool usage, code execution, and human-agent interaction…

Computation and Language · Computer Science 2025-10-09 Haofei Yu , Keyang Xuan , Fenghai Li , Kunlun Zhu , Zijie Lei , Jiaxun Zhang , Ziheng Qi , Kyle Richardson , Jiaxuan You

Modern science is reaching a critical inflection point. Instruments across disciplines, from particle physics and astronomy to genomics and climate modeling, now produce data of such scale, diversity, and interdependence that traditional…

High Energy Physics - Experiment · Physics 2026-03-10 Ke Li , Beijiang Liu , Bruce Mellado , Changzheng Yuan , Zhengde Zhang

The development of native computer-use agents (CUA) represents a significant leap in multimodal AI. However, their potential is currently bottlenecked by the constraints of static data scaling. Existing paradigms relying primarily on…

AI agents hold the potential to revolutionize scientific productivity by automating literature reviews, replicating experiments, analyzing data, and even proposing new directions of inquiry; indeed, there are now many such agents, ranging…

Scientific idea generation is a cornerstone of autonomous knowledge discovery, yet the iterative evolution required to transform initial concepts into high-quality research proposals remains a formidable challenge for Large Language Models…

Artificial Intelligence · Computer Science 2026-03-24 Andreas Sauter , Yuyue Zhao , Jacopo Urbani , Wenxiang Hu , Zaiqiao Meng , Lun Zhou , Xiaohui Yan , Yougang Lyu

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

One of the grand challenges of artificial general intelligence is developing agents capable of conducting scientific research and discovering new knowledge. While frontier models have already been used as aides to human scientists, e.g. for…

Artificial Intelligence · Computer Science 2024-09-04 Chris Lu , Cong Lu , Robert Tjarko Lange , Jakob Foerster , Jeff Clune , David Ha

Recent advances in embodied AI highlight the potential of vision language models (VLMs) as agents capable of perception, reasoning, and interaction in complex environments. However, top-performing systems rely on large-scale models that are…

The "AI Scientist" paradigm is transforming scientific research by automating key stages of the research process, from idea generation to scholarly writing. This shift is expected to accelerate discovery and expand the scope of scientific…

Human-Computer Interaction · Computer Science 2026-02-05 Keyu Zhao , Fengli Xu , Yong Li , Tie-Yan Liu

Reusable skills play a key role in improving LLM-based agents, but existing skill-evolution methods often fail to ensure that evolved skills both cover the knowledge required by the task and remain aligned with the target task. As a result,…

Computation and Language · Computer Science 2026-05-27 Dingzirui Wang , Xuanliang Zhang , Keyan Xu , Qingfu Zhu , Wanxiang Che , Yang Deng

Coding agents are increasingly used as general-purpose problem solvers, but their flexibility does not by itself confer the domain expertise needed for specialized tasks. Recent work addresses this through \textit{agent skills}: reusable…

Artificial Intelligence · Computer Science 2026-03-04 Salaheddin Alzubi , Noah Provenzano , Jaydon Bingham , Weiyuan Chen , Tu Vu

Scientific discovery is a complex cognitive process that has driven human knowledge and technological progress for centuries. While artificial intelligence (AI) has made significant advances in automating aspects of scientific reasoning,…

Machine Learning · Computer Science 2024-12-24 Chandan K Reddy , Parshin Shojaee