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Three major biomarkers: beta-amyloid (A), pathologic tau (T), and neurodegeneration (N), are recognized as valid proxies for neuropathologic changes of Alzheimer's disease. While there are extensive studies on cerebrospinal fluids…

Quantitative Methods · Quantitative Biology 2021-03-09 Qing Liu , Defu Yang , Jingwen Zhang , Ziming Wei , Guorong Wu , Minghan Chen

While many physical and engineering processes are most effectively described by non-linear symbolic models, existing non-linear symbolic regression (SR) methods are restricted to a limited set of continuous algebraic functions, thereby…

Artificial Intelligence · Computer Science 2025-01-15 Sergei Garmaev , Siddhartha Mishra , Olga Fink

Background: Despite the striking efforts in investigating neurobiological factors behind the acquisition of amyloid-\b{eta} (A), protein tau (T), and neurodegeneration ([N]) biomarkers, the mechanistic pathways of how AT[N] biomarkers…

Quantitative Methods · Quantitative Biology 2023-08-22 Jingwen Zhang , Qing Liu , Haorui Zhang , Michelle Dai , Qianqian Song , Defu Yang , Guorong Wu , Minghan Chen

Fourier Neural Operators (FNOs) have emerged as leading surrogates for solver operators for various functional problems, yet their stability, generalization and frequency behavior lack a principled explanation. We present a systematic…

Machine Learning · Computer Science 2026-02-05 Taeyoung Kim

Fourier neural operators (FNOs) can learn highly nonlinear mappings between function spaces, and have recently become a popular tool for learning responses of complex physical systems. However, to achieve good accuracy and efficiency, FNOs…

Machine Learning · Computer Science 2023-10-31 Ning Liu , Siavash Jafarzadeh , Yue Yu

Comprehending the interplay between spatial and temporal characteristics of neural dynamics can contribute to our understanding of information processing in the human brain. Graph neural networks (GNNs) provide a new possibility to…

Neurons and Cognition · Quantitative Biology 2022-04-29 Simon Wein , Alina Schüller , Ana Maria Tomé , Wilhelm M. Malloni , Mark W. Greenlee , Elmar W. Lang

We introduce a new memory architecture for navigation in previously unseen environments, inspired by landmark-based navigation in animals. The proposed semi-parametric topological memory (SPTM) consists of a (non-parametric) graph with…

Machine Learning · Computer Science 2018-03-05 Nikolay Savinov , Alexey Dosovitskiy , Vladlen Koltun

Diagnosis and prediction in some domains, like medical and industrial diagnosis, require a representation that combines uncertainty management and temporal reasoning. Based on the fact that in many cases there are few state changes in the…

Artificial Intelligence · Computer Science 2013-01-30 Gustavo Arroyo-Figueroa , Luis Enrique Sucar

Soil and groundwater contamination is a pervasive problem at thousands of locations across the world. Contaminated sites often require decades to remediate or to monitor natural attenuation. Climate change exacerbates the long-term site…

This paper proposes a physics-informed neural operator (PINO) framework for solving inverse scattering problems, enabling rapid and accurate reconstructions under diverse measurement conditions. In the proposed approach, the dielectric…

Computational Physics · Physics 2026-03-27 Q. C. Dong , Zi-Xuan Su , Qing Huo Liu , Wen Chen , Zhizhang , Chen

Time-periodic quantum systems exhibit a rich variety of far-from-equilibrium phenomena and serve as ideal platforms for quantum engineering and control. However, simulating their dynamics with conventional numerical methods remains…

Quantum Physics · Physics 2025-09-10 Zihao Qi , Yang Peng , Christopher Earls

Network topology optimization (NTO) via busbar splitting can mitigate transmission grid congestion and reduce redispatch costs. However, solving this mixed-integer nonlinear problem for large-scale systems in near-real-time is currently…

Artificial Intelligence · Computer Science 2026-03-16 Ali Rajaei , Peter Palensky , Jochen L. Cremer

Recurrent Neural Networks (RNNs) have shown great success in modeling time-dependent patterns, but there is limited research on their learned representations of latent temporal features and the emergence of these representations during…

Machine Learning · Computer Science 2023-06-13 Peter DelMastro , Rushiv Arora , Edward Rietman , Hava T. Siegelmann

Complex piezoelectric systems are foundational in industrial applications. Their performance, however, is challenged by the nonlinear voltage-displacement hysteretic relationships. Efficient characterization methods are, therefore,…

Machine Learning · Computer Science 2025-06-02 Abhishek Chandra , Taniya Kapoor , Mitrofan Curti , Koen Tiels , Elena A. Lomonova

Topology optimization is a critical task in engineering design, where the goal is to optimally distribute material in a given space for maximum performance. We introduce Neural Implicit Topology Optimization (NITO), a novel approach to…

Machine Learning · Computer Science 2024-02-08 Amin Heyrani Nobari , Giorgio Giannone , Lyle Regenwetter , Faez Ahmed

Artificial intelligence (AI) has drawn significant inspiration from neuroscience to develop artificial neural network (ANN) models. However, these models remain constrained by the Von Neumann architecture and struggle to capture the…

Neurons and Cognition · Quantitative Biology 2025-11-18 Gautier-Edouard Filardo , Thibaut Heckmann

Computing properties of molecular systems rely on estimating expectations of the (unnormalized) Boltzmann distribution. Molecular dynamics (MD) is a broadly adopted technique to approximate such quantities. However, stable simulations rely…

Chemical Physics · Physics 2023-10-31 Mathias Schreiner , Ole Winther , Simon Olsson

A permanently increasing number of on-board automotive control systems requires new approaches to their digital mapping that improves functionality in terms of adaptability and robustness as well as enables their easier on-line software…

Systems and Control · Electrical Eng. & Systems 2022-07-20 Moritz Zink , Martin Schiele , Valentin Ivanov

Multiple operator learning concerns learning operator families $\{G[\alpha]:U\to V\}_{\alpha\in W}$ indexed by an operator descriptor $\alpha$. Training data are collected hierarchically by sampling operator instances $\alpha$, then input…

Machine Learning · Computer Science 2026-04-03 Adrien Weihs , Hayden Schaeffer

In this article, we present a framework for designing neural networks that remain consistent with the underlying principles of agent-based models. We begin by highlighting the limitations of standard neural differential equations in…

Machine Learning · Computer Science 2025-12-10 Nino Antulov-Fantulin
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