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The interaction of a protein with its environment can be understood and controlled via its 3D structure. Experimental methods for protein structure determination, such as X-ray crystallography or cryogenic electron microscopy, shed light on…

Machine Learning · Computer Science 2025-04-24 Axel Levy , Eric R. Chan , Sara Fridovich-Keil , Frédéric Poitevin , Ellen D. Zhong , Gordon Wetzstein

We present a novel approach for generating minority samples that live on low-density regions of a data manifold. Our framework is built upon diffusion models, leveraging the principle of guided sampling that incorporates an arbitrary…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Soobin Um , Jong Chul Ye

Image synthesis approaches, e.g., generative adversarial networks, have been popular as a form of data augmentation in medical image analysis tasks. It is primarily beneficial to overcome the shortage of publicly accessible data and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-05 Shiyi Du , Xiaosong Wang , Yongyi Lu , Yuyin Zhou , Shaoting Zhang , Alan Yuille , Kang Li , Zongwei Zhou

Recent 3D large reconstruction models typically employ a two-stage process, including first generate multi-view images by a multi-view diffusion model, and then utilize a feed-forward model to reconstruct images to 3D content.However,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Zhenyu Tang , Junwu Zhang , Xinhua Cheng , Wangbo Yu , Chaoran Feng , Yatian Pang , Bin Lin , Li Yuan

A fundamental challenge in text-to-3D face generation is achieving high-quality geometry. The core difficulty lies in the arbitrary and intricate distribution of vertices in 3D space, making it challenging for existing models to establish…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Junyi Zhang , Yiming Wang , Yunhong Lu , Qichao Wang , Wenzhe Qian , Xiaoyin Xu , David Gu , Min Zhang

This paper presents a novel approach to generating the 3D motion of a human interacting with a target object, with a focus on solving the challenge of synthesizing long-range and diverse motions, which could not be fulfilled by existing…

Computer Vision and Pattern Recognition · Computer Science 2023-10-04 Huaijin Pi , Sida Peng , Minghui Yang , Xiaowei Zhou , Hujun Bao

Diffusion-based image generators can now produce high-quality and diverse samples, but their success has yet to fully translate to 3D generation: existing diffusion methods can either generate low-resolution but 3D consistent outputs, or…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Animesh Karnewar , Niloy J. Mitra , Andrea Vedaldi , David Novotny

In this paper we describe a novel framework for diffusion-based generative modeling on constrained spaces. In particular, we introduce manual bridges, a framework that expands the kinds of constraints that can be practically used to form…

Machine Learning · Computer Science 2025-02-28 Saeid Naderiparizi , Xiaoxuan Liang , Berend Zwartsenberg , Frank Wood

The structure of topology underpins much of the research on performance and robustness, yet available topology data are typically scarce, necessitating the generation of synthetic graphs with desired properties for testing or release. Prior…

Machine Learning · Computer Science 2025-12-24 Gongli Xi , Ye Tian , Mengyu Yang , Zhenyu Zhao , Yuchao Zhang , Xiangyang Gong , Xirong Que , Wendong Wang

Creating large-scale datasets for training high-performance generative models is often prohibitively expensive, especially when associated attributes or annotations must be provided. As a result, merging existing datasets has become a…

Machine Learning · Statistics 2026-03-31 Yanfeng Yang , Kenji Fukumizu

Deep generative diffusion models are a promising avenue for 3D de novo molecular design in materials science and drug discovery. However, their utility is still limited by suboptimal performance on large molecular structures and limited…

Machine Learning · Computer Science 2023-11-27 Tuan Le , Julian Cremer , Frank Noé , Djork-Arné Clevert , Kristof Schütt

Diffusion models have made breakthroughs in 3D generation tasks. Current 3D diffusion models focus on reconstructing target shape from images or a set of partial observations. While excelling in global context understanding, they struggle…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Yuanbo Wang , Zhaoxuan Zhang , Jiajin Qiu , Dilong Sun , Zhengyu Meng , Xiaopeng Wei , Xin Yang

Anatomy shape modeling is a fundamental problem in medical data analysis. However, the geometric complexity and topological variability of anatomical structures pose significant challenges to accurate anatomical shape generation. In this…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Guoqing Zhang , Jingyun Yang , Siqi Chen , Anping Zhang , Yang Li

Recent experiments have been able to visualise chromosome organization in fast-growing E.coli cells. However, the mechanism underlying the spatio-temporal organization remains poorly understood. We propose that the DNA adopts a specific…

Soft Condensed Matter · Physics 2026-04-06 Shreerang Pande , Debarshi Mitra , Apratim Chatterji

Note: The final version of this article was published in Computers and Geosciences, Volume 206, January 2026, 106038. DOI: 10.1016/j.cageo.2025.106038. Readers should refer to the published version for the most up-to-date content.…

This paper presents a novel framework for modeling and conditional generation of 3D articulated objects. Troubled by flexibility-quality tradeoffs, existing methods are often limited to using predefined structures or retrieving shapes from…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Jiayi Su , Youhe Feng , Zheng Li , Jinhua Song , Yangfan He , Botao Ren , Botian Xu

For domains that involve numerical simulation, it can be computationally expensive to run an ensemble of simulations spanning a parameter space of interest to a user. To this end, an attractive surrogate for simulation is the generative…

Machine Learning · Computer Science 2025-05-13 Xiaohan Wang , Matthew Berger

We use hierarchical procedural rules for the generation of control maps within the stable diffusion framework to produce photo-realistic architectural facade images. Starting from a single input image and its segmentation, we apply an…

Graphics · Computer Science 2026-05-15 Aleksander Plocharski , Jan Swidzinski , Przemyslaw Musialski

We present LTM3D, a Latent Token space Modeling framework for conditional 3D shape generation that integrates the strengths of diffusion and auto-regressive (AR) models. While diffusion-based methods effectively model continuous latent…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Xin Kang , Zihan Zheng , Lei Chu , Yue Gao , Jiahao Li , Hao Pan , Xuejin Chen , Yan Lu

Diffusion probabilistic models have achieved remarkable success in text guided image generation. However, generating 3D shapes is still challenging due to the lack of sufficient data containing 3D models along with their descriptions.…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Zijie Wu , Yaonan Wang , Mingtao Feng , He Xie , Ajmal Mian