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Functional magnetic resonance (fMRI) is an invaluable tool in studying cognitive processes in vivo. Many recent studies use functional connectivity (FC), partial correlation connectivity (PC), or fMRI-derived brain networks to predict…

Neurons and Cognition · Quantitative Biology 2023-08-04 Anton Orlichenko , Gang Qu , Kuan-Jui Su , Anqi Liu , Hui Shen , Hong-Wen Deng , Yu-Ping Wang

Predicting behavioral variables from neuroimaging modalities such as magnetic resonance imaging (MRI) has the potential to allow the development of neuroimaging biomarkers of mental and neurological disorders. A crucial processing step to…

Neurons and Cognition · Quantitative Biology 2025-07-29 Mikkel Schöttner Sieler , Thomas A. W. Bolton , Jagruti Patel , Patric Hagmann

MP-PCA denoising has become the method of choice for denoising in MRI since it provides an objective threshold to separate the desired signal from unwanted thermal noise components. In rodents, thermal noise in the coils is an important…

Medical Physics · Physics 2022-11-29 Francisca F. Fernandes , Jonas L. Olesen , Sune N. Jespersen , Noam Shemesh

Motivated by the inquiries of weak signals in underpowered genome-wide association studies (GWASs), we consider the problem of retaining true signals that are not strong enough to be individually separable from a large amount of noise. We…

Methodology · Statistics 2024-02-05 X. Jessie Jeng , Yifei Hu , Quan Sun , Yun Li

We consider the challenges in extracting stimulus-related neural dynamics from other intrinsic processes and noise in naturalistic functional magnetic resonance imaging (fMRI). Most studies rely on inter-subject correlations (ISC) of…

Neurons and Cognition · Quantitative Biology 2021-02-23 Chee-Ming Ting , Jeremy I. Skipper , Steven L. Small , Hernando Ombao

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

Neurons and Cognition · Quantitative Biology 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

The extraction of brain functioning features is a crucial step in the definition of brain-computer interfaces (BCIs). In the last decade, functional connectivity (FC) estimators have been increasingly explored based on their ability to…

Neurons and Cognition · Quantitative Biology 2019-12-06 Tiziana Cattai , Stefania Colonnese , Marie-Constance Corsi , Danielle S. Bassett , Gaetano Scarano , Fabrizio De Vico Fallani

Resting state functional MRI (rs-fMRI) is a widespread and powerful tool for investigating functional connectivity and brain disorders. However, functional connectivity analysis can be seriously affected by random and structured noise from…

Neurons and Cognition · Quantitative Biology 2021-04-01 Yujian Diao , Ting Yin , Rolf Gruetter , Ileana O. Jelescu

A great improvement to the insight on brain function that we can get from fMRI data can come from effective connectivity analysis, in which the flow of information between even remote brain regions is inferred by the parameters of a…

Neurons and Cognition · Quantitative Biology 2012-08-21 G. Wu , W. Liao , S. Stramaglia , J. Ding , H. Chen , D. Marinazzo

In recent years,the application of deep learning in task functional Magnetic Resonance Imaging (tfMRI) decoding has led to significant advancements. However,most studies remain constrained by assumption of temporal stationarity in neural…

Machine Learning · Computer Science 2025-03-05 Yueyang Wu , Sinan Yang , Yanming Wang , Jiajie He , Muhammad Mohsin Pathan , Bensheng Qiu , Xiaoxiao Wang

In this paper, we use data from the Human Connectome Project (N=461) to investigate the effect of scan length on reliability of resting-state functional connectivity (rsFC) estimates produced from resting-state functional magnetic resonance…

Applications · Statistics 2016-06-22 Amanda F. Mejia , Mary Beth Nebel , Anita D. Barber , Ann S. Choe , Martin A. Lindquist

Functional connectivity (FC) analysis of resting-state fMRI data provides a framework for characterizing brain networks and their association with participant-level covariates. Due to the high dimensionality of neuroimaging data, standard…

Methodology · Statistics 2025-08-18 Wei Zhao , Brian J. Reich , Emily C. Hector

Increasing use of CT in modern medical practice has raised concerns over associated radiation dose. Reduction of radiation dose associated with CT can increase noise and artifacts, which can adversely affect diagnostic confidence. Denoising…

Computer Vision and Pattern Recognition · Computer Science 2017-02-24 Qingsong Yang , Pingkun Yan , Mannudeep K. Kalra , Ge Wang

Fast Magnetic Resonance Imaging (MRI) is highly in demand for many clinical applications in order to reduce the scanning cost and improve the patient experience. This can also potentially increase the image quality by reducing the motion…

Computer Vision and Pattern Recognition · Computer Science 2017-05-23 Simiao Yu , Hao Dong , Guang Yang , Greg Slabaugh , Pier Luigi Dragotti , Xujiong Ye , Fangde Liu , Simon Arridge , Jennifer Keegan , David Firmin , Yike Guo

Since initial reports regarding the impact of motion artifact on measures of functional connectivity, there has been a proliferation of confound regression methods to limit its impact. However, recent techniques have not been systematically…

In this paper, we propose a method for denoising diffusion-weighted images (DWI) of the brain using a convolutional neural network trained on realistic, synthetic MR data. We compare our results to averaging of repeated scans, a widespread…

Image and Video Processing · Electrical Eng. & Systems 2022-06-02 Jakub Jurek , Andrzej Materka , Kamil Ludwisiak , Agata Majos , Kamil Gorczewski , Kamil Cepuch , Agata Zawadzka

Functional magnetic resonance imaging (fMRI) data have become increasingly available and are useful for describing functional connectivity (FC), the relatedness of neuronal activity in regions of the brain. This FC of the brain provides…

Machine Learning · Statistics 2020-10-14 Andrew DiLernia , Karina Quevedo , Jazmin Camchong , Kelvin Lim , Wei Pan , Lin Zhang

On one hand, the transmitted ultrasound beam gets attenuated as propagates through the tissue. On the other hand, the received Radio-Frequency (RF) data contains an additive Gaussian noise which is brought about by the acquisition card and…

Image and Video Processing · Electrical Eng. & Systems 2022-01-10 Sobhan Goudarzi , Hassan Rivaz

Most packages for the analysis of fMRI-based functional connectivity (FC) and genomic data are used with a programming language interface, lacking an easy-to-navigate GUI frontend. This exacerbates two problems found in these types of data:…

Populations and Evolution · Quantitative Biology 2023-10-13 Anton Orlichenko , Grant Daly , Ziyu Zhou , Anqi Liu , Hui Shen , Hong-Wen Deng , Yu-Ping Wang

Artifacts in functional MRI (fMRI) data cause deviations from common distributional assumptions, introduce spatial and temporal outliers, and reduce the signal-to-noise ratio of the data -- all of which can have negative consequences for…

Applications · Statistics 2023-03-06 Damon Pham , Daniel McDonald , Lei Ding , Mary Beth Nebel , Amanda Mejia
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