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Age related macular degeneration (AMD) is one of the major causes for blindness in the elderly population. In this report, we propose deep learning based methods for retinal analysis using color fundus images for computer aided diagnosis of…

Image and Video Processing · Electrical Eng. & Systems 2020-09-04 Sharath M Shankaranarayana

Vessel tracing by modeling vascular structures in 3D medical images with centerlines and radii can provide useful information for vascular health. Existing algorithms have been developed but there are certain persistent problems such as…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Li Chen , Wenjin Liu , Niranjan Balu , Mahmud Mossa-Basha , Thomas S. Hatsukami , Jenq-Neng Hwang , Chun Yuan

Although Digital Subtraction Angiography (DSA) is the most important imaging for visualizing cerebrovascular anatomy, its interpretation by clinicians remains difficult. This is particularly true when treating arteriovenous malformations…

Image and Video Processing · Electrical Eng. & Systems 2024-02-16 Kathleen Baur , Xin Xiong , Erickson Torio , Rose Du , Parikshit Juvekar , Reuben Dorent , Alexandra Golby , Sarah Frisken , Nazim Haouchine

In this study, we develop a novel methodology for annotating the brain vasculature using dynamic 4D-CTA head scans. By using multiple time points from dynamic CTA acquisitions, we subtract bone and soft tissue to enhance the visualization…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Alberto Mario Ceballos-Arroyo , Shrikanth M. Yadav , Chu-Hsuan Lin , Jisoo Kim , Geoffrey S. Young , Lei Qin , Huaizu Jiang

Automated detection of retinal structures, such as retinal vessels (RV), the foveal avascular zone (FAZ), and retinal vascular junctions (RVJ), are of great importance for understanding diseases of the eye and clinical decision-making. In…

Image and Video Processing · Electrical Eng. & Systems 2022-08-24 Jinkui Hao , Ting Shen , Xueli Zhu , Yonghuai Liu , Ardhendu Behera , Dan Zhang , Bang Chen , Jiang Liu , Jiong Zhang , Yitian Zhao

While there have been increased researches using deep learning techniques for the extraction of vascular structure from the 2D en face OCTA, for such approach, it is known that the data annotation process on the curvilinear structure like…

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Many eye diseases like Diabetic Macular Edema (DME), Age-related Macular Degeneration (AMD), and Glaucoma manifest in the retina, can cause irreversible blindness or severely impair the central version. The Optical Coherence Tomography…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Nchongmaje Ndipenoch , Alina Miron , Zidong Wang , Yongmin Li

Automated vascular segmentation on optical coherence tomography angiography (OCTA) is important for the quantitative analyses of retinal microvasculature in neuroretinal and systemic diseases. Despite recent improvements, artifacts continue…

Image and Video Processing · Electrical Eng. & Systems 2021-04-22 Yih-Cherng Lee , Ling Yeung

We propose a fully automated algorithm based on a deep learning framework enabling screening of a coronary computed tomography angiography (CCTA) examination for confident detection of the presence or absence of coronary artery…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Sema Candemir , Richard D. White , Mutlu Demirer , Vikash Gupta , Matthew T. Bigelow , Luciano M. Prevedello , Barbaros S. Erdal

Optical coherence tomography angiography (OCTA) is a novel non-invasive imaging technique that allows visualizations of vasculature and foveal avascular zone (FAZ) across retinal layers. Clinical researches suggest that the morphology and…

Image and Video Processing · Electrical Eng. & Systems 2021-07-14 Li Lin , Zhonghua Wang , Jiewei Wu , Yijin Huang , Junyan Lyu , Pujin Cheng , Jiong Wu , Xiaoying Tang

Automated drusen segmentation in retinal optical coherence tomography (OCT) scans is relevant for understanding age-related macular degeneration (AMD) risk and progression. This task is usually performed by segmenting the top/bottom…

Image and Video Processing · Electrical Eng. & Systems 2019-07-25 Rhona Asgari , José Ignacio Orlando , Sebastian Waldstein , Ferdinand Schlanitz , Magdalena Baratsits , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Background: Computed Tomography Angiography (CTA) is crucial for cerebrovascular disease diagnosis. Dynamic CTA is a type of imaging that captures temporal information about the We aim to develop and evaluate two segmentation techniques to…

Medical Physics · Physics 2025-02-17 Shrikanth Yadav , Jisoo Kim , Geoffrey Young , Lei Qin

Background: Patients with neovascular age-related macular degeneration (AMD) can avoid vision loss via certain therapy. However, methods to predict the progression to neovascular age-related macular degeneration (nvAMD) are lacking.…

Computer Vision and Pattern Recognition · Computer Science 2019-04-12 Boris Babenko , Siva Balasubramanian , Katy E. Blumer , Greg S. Corrado , Lily Peng , Dale R. Webster , Naama Hammel , Avinash V. Varadarajan

Retinal vessel segmentation is a vital step for the diagnosis of many early eye-related diseases. In this work, we propose a new deep learning model, namely Channel Attention Residual U-Net (CAR-UNet), to accurately segment retinal vascular…

Image and Video Processing · Electrical Eng. & Systems 2020-10-22 Changlu Guo , Márton Szemenyei , Yangtao Hu , Wenle Wang , Wei Zhou , Yugen Yi

Computed Tomography Angiography is a key modality providing insights into the cerebrovascular vessel tree that are crucial for the diagnosis and treatment of ischemic strokes, in particular in cases of large vessel occlusions (LVO). Thus,…

Image and Video Processing · Electrical Eng. & Systems 2022-05-06 Florian Thamm , Oliver Taubmann , Markus Jürgens , Hendrik Ditt , Andreas Maier

Automated optic disc (OD) and optic cup (OC) segmentation in fundus images is relevant to efficiently measure the vertical cup-to-disc ratio (vCDR), a biomarker commonly used in ophthalmology to determine the degree of glaucomatous optic…

Optical coherence tomography angiography (OCTA) can non-invasively image the eye's circulatory system. In order to reliably characterize the retinal vasculature, there is a need to automatically extract quantitative metrics from these…

Image and Video Processing · Electrical Eng. & Systems 2022-07-25 Martin J. Menten , Johannes C. Paetzold , Alina Dima , Bjoern H. Menze , Benjamin Knier , Daniel Rueckert

Systemic diseases such as diabetes, hypertension, atherosclerosis are among the leading causes of annual human mortality rate. It is suggested that retinal and conjunctival vascular tortuosity is a potential biomarker for such systemic…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Ashwin De Silva , Malsha V. Perera , Navodini Wijethilake , Saroj Jayasinghe , Nuwan D. Nanayakkara , Anjula De Silva

Atherosclerosis, a chronic inflammatory disease affecting the large arteries, presents a global health risk. Accurate analysis of diagnostic images, like computed tomographic angiograms (CTAs), is essential for staging and monitoring the…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Alireza Bagheri Rajeoni , Breanna Pederson , Daniel G. Clair , Susan M. Lessner , Homayoun Valafar