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Related papers: HARP: HARmonizing in-vivo diffusion MRI using Phan…

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Harmonization improves data consistency and is central to effective integration of diverse imaging data acquired across multiple sites. Recent deep learning techniques for harmonization are predominantly supervised in nature and hence…

Image and Video Processing · Electrical Eng. & Systems 2021-10-04 Siyuan Liu , Pew-Thian Yap

Diffusion imaging is an important method in the field of neuroscience, as it is sensitive to changes within the tissue microstructure of the human brain. However, a major challenge when using MRI to derive quantitative measures is that the…

Computer Vision and Pattern Recognition · Computer Science 2018-08-07 Simon Koppers , Luke Bloy , Jeffrey I. Berman , Chantal M. W. Tax , J. Christopher Edgar , Dorit Merhof

Diffusion magnetic resonance imaging is a noninvasive imaging technique that can indirectly infer the microstructure of tissues and provide metrics which are subject to normal variability across subjects. Potentially abnormal values or…

Image and Video Processing · Electrical Eng. & Systems 2020-08-28 Samuel St-Jean , Max A. Viergever , Alexander Leemans

For machine learning-based prognosis and diagnosis of rare diseases, such as pediatric brain tumors, it is necessary to gather medical imaging data from multiple clinical sites that may use different devices and protocols. Deep…

In MRI, images of the same contrast (e.g., T$_1$) from the same subject can exhibit noticeable differences when acquired using different hardware, sequences, or scan parameters. These differences in images create a domain gap that needs to…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Hwihun Jeong , Heejoon Byun , Dong Un Kang , Jongho Lee

Three-dimensional (3D) multi-slab imaging is a promising approach for high-resolution in vivo diffusion MRI (dMRI) due to its compatibility with short TR (1-2 s), providing optimal signal-to-noise ratio (SNR) efficiency. A major challenge,…

Medical Physics · Physics 2026-02-10 Ziyu Li , Karla L. Miller , Wenchuan Wu

In MRI, variations in scan parameters, sequence, or hardware can lead to discrepancies in image appearance, even for the same subject. These inconsistencies, known as domain shifts, can hinder image analysis and degrade the performance of…

Image and Video Processing · Electrical Eng. & Systems 2026-05-05 Minjun Kim , Dong Ju Mun , Hwihun Jeong , Hangyeol Park , Haechang Lee , Se Young Chun , Jongho Lee

Harmonization of T1-weighted MR images across different scanners is crucial for ensuring consistency in neuroimaging studies. This study introduces a novel approach to direct image harmonization, moving beyond feature standardization to…

Purpose: In the present work we describe the correction of diffusion-weighted MRI for site and scanner biases using a novel method based on invariant representation. Theory and Methods: Pooled imaging data from multiple sources are subject…

Quantitative Methods · Quantitative Biology 2020-02-04 Daniel Moyer , Greg Ver Steeg , Chantal M. W. Tax , Paul M. Thompson

Multi-site structural MRI is increasingly used in neuroimaging studies to diversify subject cohorts. However, combining MR images acquired from various sites/centers may introduce site-related non-biological variations. Retrospective image…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Mengqi Wu , Minhui Yu , Shuaiming Jing , Pew-Thian Yap , Zhengwu Zhang , Mingxia Liu

Diffusion MRI (dMRI) is a valuable tool to map brain microstructure and connectivity by analyzing water molecule diffusion in tissue. However, acquiring dMRI data requires to capture multiple 3D brain volumes in a short time, often leading…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Sedigheh Dargahi , Sylvain Bouix , Christian Desrosiers

Multi-center neuroimaging studies face technical variability due to batch differences across sites, which potentially hinders data aggregation and impacts study reliability.Recent efforts in neuroimaging harmonization have aimed to minimize…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Haoyu Lan , Bino A. Varghese , Nasim Sheikh-Bahaei , Farshid Sepehrband , Arthur W Toga , Jeiran Choupan

Conventional and deep learning-based methods have shown great potential in the medical imaging domain, as means for deriving diagnostic, prognostic, and predictive biomarkers, and by contributing to precision medicine. However, these…

The ability to combine data across scanners and studies is vital for neuroimaging, to increase both statistical power and the representation of biological variability. However, combining datasets across sites leads to two challenges: first,…

Machine Learning · Computer Science 2022-06-01 Nicola K Dinsdale , Mark Jenkinson , Ana IL Namburete

Artificial intelligence (AI) has introduced numerous opportunities for human assistance and task automation in medicine. However, it suffers from poor generalization in the presence of shifts in the data distribution. In the context of…

Many diffusion MRI researchers, including the Human Connectome Project (HCP), acquire data using multishell (e.g., WU-Minn consortium) and diffusion spectrum imaging (DSI) schemes (e.g., USC-Harvard consortium). However, these data sets are…

Neurons and Cognition · Quantitative Biology 2023-07-28 Fang-Cheng Yeh , Timothy D. Verstynen

Aggregating multi-site brain MRI data can enhance deep learning model training, but also introduces non-biological heterogeneity caused by site-specific variations (e.g., differences in scanner vendors, acquisition parameters, and imaging…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Mengqi Wu , Yongheng Sun , Qianqian Wang , Pew-Thian Yap , Mingxia Liu

Deployment of machine learning algorithms into real-world practice is still a difficult task. One of the challenges lies in the unpredictable variability of input data, which may differ significantly among individual users, institutions,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Roman Stoklasa

Magnetic resonance imaging (MRI) has greatly advanced neuroscience research and clinical diagnostics. However, imaging data collected across different scanners, acquisition protocols, or imaging sites often exhibit substantial…

Image and Video Processing · Electrical Eng. & Systems 2026-04-02 Qinqin Yang , Firoozeh Shomal-Zadeh , Ali Gholipour

Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 William Consagra , Lipeng Ning , Yogesh Rathi
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