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Objective. This paper presents an overview of generalizable and explainable artificial intelligence (XAI) in deep learning (DL) for medical imaging, aimed at addressing the urgent need for transparency and explainability in clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Ahmad Chaddad , Yan Hu , Yihang Wu , Binbin Wen , Reem Kateb

Deep Neural Networks have become the dominant solution for Autonomous Driving perception, but their opacity conflicts with emerging Trustworthy AI guidelines and complicates safety assurance, debugging, and human oversight. While…

Robotics · Computer Science 2026-05-25 Till Beemelmanns , Shayan Sharifi , Manas Mehrotra , Ayushman Choudhuri , Lutz Eckstein

Explaining deep learning models is essential for clinical integration of medical image analysis systems. A good explanation highlights if a model depends on spurious features that undermines generalization and harms a subset of patients or,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Yoni Schirris , Eric Marcus , Jonas Teuwen , Hugo Horlings , Efstratios Gavves

The integration of Artificial Intelligence (AI) into high-stakes domains such as healthcare, finance, and autonomous systems is often constrained by concerns over transparency, interpretability, and trust. While Human-Centered AI (HCAI)…

Human-Computer Interaction · Computer Science 2025-04-29 Chameera De Silva , Thilina Halloluwa , Dhaval Vyas

Modern deep neural networks have now reached human-level performance across a variety of tasks. However, unlike humans they lack the ability to explain their decisions by showing where and telling what concepts guided them. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Itay Benou , Tammy Riklin-Raviv

Convolutional neural networks (CNNs) are widely used for high-stakes applications like medicine, often surpassing human performance. However, most explanation methods rely on post-hoc attribution, approximating the decision-making process…

Machine Learning · Computer Science 2026-02-23 Kerol Djoumessi , Philipp Berens

The field of Explainable Artificial Intelligence (XAI) aims to improve the interpretability of black-box machine learning models. Building a heatmap based on the importance value of input features is a popular method for explaining the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Amirhossein Aminimehr , Pouya Khani , Amirali Molaei , Amirmohammad Kazemeini , Erik Cambria

In recent years, Explainable AI (XAI) methods have facilitated profound validation and knowledge extraction from ML models. While extensively studied for classification, few XAI solutions have addressed the challenges specific to regression…

Machine Learning · Computer Science 2025-07-21 Simon Letzgus , Klaus-Robert Müller , Grégoire Montavon

Artificial Intelligence (AI) has become essential for analyzing complex data and solving highly-challenging tasks. It is being applied across numerous disciplines beyond computer science, including Food Engineering, where there is a growing…

Explainable Artificial Intelligence (xAI) has the potential to enhance the transparency and trust of AI-based systems. Although accurate predictions can be made using Deep Neural Networks (DNNs), the process used to arrive at such…

Computer Vision and Pattern Recognition · Computer Science 2024-08-09 Bhushan Atote , Victor Sanchez

The development of many vision models mainly focuses on improving their performance using metrics such as accuracy, IoU, and mAP, with less attention to explainability due to the complexity of applying xAI methods to provide a meaningful…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Phu-Vinh Nguyen , Tan-Hanh Pham , Chris Ngo , Truong Son Hy

Recent brain tumor classification methods often report high accuracy but rely on deep, over-parameterized architectures with limited interpretability, making it difficult to determine whether predictions are driven by tumor-relevant…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Rajan Das Gupta , Md Imrul Hasan Showmick , Lei Wei , Mushfiqur Rahman Abir , Shanjida Akter , Md. Yeasin Rahat , Md. Jakir Hossen

As machine learning models and autonomous agents are increasingly deployed in high-stakes, real-world domains such as healthcare, security, finance, and robotics, the need for transparent and trustworthy explanations has become critical. To…

Artificial Intelligence · Computer Science 2025-05-29 Haishi Bai , Jozo Dujmovic , Jianwu Wang

Explainable AI aims to render model behavior understandable by humans, which can be seen as an intermediate step in extracting causal relations from correlative patterns. Due to the high risk of possible fatal decisions in image-based…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Lukas Klein , João B. S. Carvalho , Mennatallah El-Assady , Paolo Penna , Joachim M. Buhmann , Paul F. Jaeger

Explainable Artificial Intelligence (XAI) aims to make learning machines less opaque, and offers researchers and practitioners various tools to reveal the decision-making strategies of neural networks. In this work, we investigate how XAI…

Machine Learning · Computer Science 2023-11-15 Dennis Grinwald , Kirill Bykov , Shinichi Nakajima , Marina M. -C. Höhne

Explainable AI (XAI) has become critical as transformer-based models are deployed in high-stakes applications including healthcare, legal systems, and financial services, where opacity hinders trust and accountability. Transformers…

Computation and Language · Computer Science 2026-01-22 George Mihaila

Convolutional Neural Networks (CNNs) are frequently and successfully used in medical prediction tasks. They are often used in combination with transfer learning, leading to improved performance when training data for the task are scarce.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Marta Oliveira , Rick Wilming , Benedict Clark , Céline Budding , Fabian Eitel , Kerstin Ritter , Stefan Haufe

Medical image classification is crucial for supporting healthcare professionals in decision-making and training. While Convolutional Neural Networks (CNNs) have traditionally dominated this field, Transformer-based models are gaining…

Computer Vision and Pattern Recognition · Computer Science 2024-10-11 S. Park , J. Kim

The impressive performance of deep learning models, particularly Convolutional Neural Networks (CNNs), is often hindered by their lack of interpretability, rendering them "black boxes." This opacity raises concerns in critical areas like…

Artificial Intelligence · Computer Science 2024-10-23 John M. Willis

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Cristiano Patrício , João C. Neves , Luís F. Teixeira
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