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Protein Language Models (PLMs), pre-trained on extensive evolutionary data from natural proteins, have emerged as indispensable tools for protein design. While powerful, PLMs often struggle to produce proteins with precisely specified…

Biomolecules · Quantitative Biology 2025-09-15 Long-Kai Huang , Rongyi Zhu , Bing He , Jianhua Yao

It is a critical challenge to efficiently unlock the powerful reasoning potential of Large Language Models (LLMs) for specific tasks or new distributions. Existing test-time adaptation methods often require tuning model parameters, which is…

Computation and Language · Computer Science 2025-12-05 Xinyue Kang , Diwei Shi , Li Chen

Large Language Models (LLMs) have shown impressive potential to simulate human behavior. We identify a fundamental challenge in using them to simulate experiments: when LLM-simulated subjects are blind to the experimental design (as is…

Artificial Intelligence · Computer Science 2025-11-25 George Gui , Olivier Toubia

In-context learning (ICL) has transformed the use of large language models (LLMs) for NLP tasks, enabling few-shot learning by conditioning on labeled examples without finetuning. Despite its effectiveness, ICL is prone to errors,…

Computation and Language · Computer Science 2025-03-21 Mario Sanz-Guerrero , Katharina von der Wense

Foundation models based on large language models (LLMs) have shown great success in handling various tasks and modalities. However, adapting these models for general-purpose audio-language tasks is challenging due to differences in acoustic…

Artificial Intelligence · Computer Science 2025-05-27 Pooneh Mousavi , Shubham Gupta , Cem Subakan , Mirco Ravanelli

Recent research explores optimization using large language models (LLMs) by either iteratively seeking next-step solutions from LLMs or directly prompting LLMs for an optimizer. However, these approaches exhibit inherent limitations,…

Optimization and Control · Mathematics 2024-03-06 Zeyuan Ma , Hongshu Guo , Jiacheng Chen , Guojun Peng , Zhiguang Cao , Yining Ma , Yue-Jiao Gong

Given the great success of large language models (LLMs) across various tasks, in this paper, we introduce LLM-ST, a novel and effective speech translation model constructed upon a pre-trained LLM. By integrating the large language model…

Computation and Language · Computer Science 2023-12-22 Zhichao Huang , Rong Ye , Tom Ko , Qianqian Dong , Shanbo Cheng , Mingxuan Wang , Hang Li

Large Language Models (LLMs) have demonstrated remarkable performance across diverse tasks and exhibited impressive reasoning abilities by applying zero-shot Chain-of-Thought (CoT) prompting. However, due to the evolving nature of sentence…

Computation and Language · Computer Science 2024-02-09 Feihu Jin , Yifan Liu , Ying Tan

Recent advances in Large Reasoning Models (LRMs) have demonstrated remarkable capabilities in solving complex tasks such as mathematics and coding. However, these models frequently exhibit a phenomenon known as overthinking during…

Machine Learning · Computer Science 2025-11-18 Yao Huang , Huanran Chen , Shouwei Ruan , Yichi Zhang , Xingxing Wei , Yinpeng Dong

Large language models (LLMs) achieve remarkable advancements by leveraging tools to interact with environments, a critical step toward generalized AI. However, the standard supervised fine-tuning (SFT) approach, which relies on large-scale…

Computation and Language · Computer Science 2025-08-27 Junjie Ye , Yilong Wu , Sixian Li , Yuming Yang , Zhiheng Xi , Tao Gui , Qi Zhang , Xuanjing Huang , Peng Wang , Zhongchao Shi , Jianping Fan , Zhengyin Du

We propose to utilize an instruction-tuned large language model (LLM) for guiding the text generation process in automatic speech recognition (ASR). Modern large language models (LLMs) are adept at performing various text generation tasks…

Audio and Speech Processing · Electrical Eng. & Systems 2025-01-08 Yosuke Higuchi , Tetsuji Ogawa , Tetsunori Kobayashi

Modern large language models (LLMs) have demonstrated impressive capabilities at sophisticated tasks, often through step-by-step reasoning similar to humans. This is made possible by their strong few and zero-shot abilities -- they can…

Computation and Language · Computer Science 2023-05-24 Xingchen Wan , Ruoxi Sun , Hanjun Dai , Sercan O. Arik , Tomas Pfister

Autonomous driving has made significant strides through data-driven techniques, achieving robust performance in standardized tasks. However, existing methods frequently overlook user-specific preferences, offering limited scope for…

Robotics · Computer Science 2025-05-13 Chengkai Xu , Jiaqi Liu , Yicheng Guo , Yuhang Zhang , Peng Hang , Jian Sun

Supervised Fine-Tuning (SFT) Large Language Models (LLM) fundamentally rely on high-quality training data. While data selection and data synthesis are two common strategies to improve data quality, existing approaches often face limitations…

Computation and Language · Computer Science 2025-10-23 Zinan Tang , Xin Gao , Qizhi Pei , Zhuoshi Pan , Mengzhang Cai , Jiang Wu , Conghui He , Lijun Wu

Large language models (LLMs) excel at complex reasoning when they include intermediate steps, known as "chains of thought" (CoTs). However, these rationales are often overly verbose, even for simple problems, leading to wasted context,…

Artificial Intelligence · Computer Science 2025-07-09 Seyedarmin Azizi , Erfan Baghaei Potraghloo , Massoud Pedram

Large language models (LLMs) have shown remarkable in-context learning (ICL) capabilities, yet their potential for sequential decision-making remains underexplored. In this paper, we study the ICL capabilities of LLMs in sequential…

Machine Learning · Computer Science 2026-05-12 Minmin Zhang , Sina Aghaei , Soroush Saghafian

In-Context Learning (ICL) empowers Large Language Models (LLMs) for rapid task adaptation without Fine-Tuning (FT), but its reliance on demonstration selection remains a critical challenge. While many-shot ICL shows promising performance…

Computation and Language · Computer Science 2025-06-06 Jianfei Zhang , Bei Li , Jun Bai , Rumei Li , Yanmeng Wang , Chenghua Lin , Wenge Rong

The remarkable performance of Large Language Models (LLMs) can be enhanced with test-time computation, which relies on external tools and even other deep learning models. However, existing approaches for integrating non-text modality…

Computation and Language · Computer Science 2025-12-12 Tianle Zhang , Wanlong Fang , Jonathan Woo , Paridhi Latawa , Deepak A. Subramanian , Alvin Chan

This paper presents a novel approach to enhance autonomous robotic manipulation using the Large Language Model (LLM) for logical inference, converting high-level language commands into sequences of executable motion functions. The proposed…

Robotics · Computer Science 2023-08-30 Haokun Liu , Yaonan Zhu , Kenji Kato , Izumi Kondo , Tadayoshi Aoyama , Yasuhisa Hasegawa

Multimodal LLMs (MLLMs) have reached remarkable levels of proficiency in understanding multimodal inputs. However, understanding and interpreting the behavior of such complex models is a challenging task, not to mention the dynamic shifts…

Artificial Intelligence · Computer Science 2025-08-14 Pegah Khayatan , Mustafa Shukor , Jayneel Parekh , Arnaud Dapogny , Matthieu Cord