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Semantic segmentation is a fundamental computer vision task with a vast number of applications. State of the art methods increasingly rely on deep learning models, known to incorrectly estimate uncertainty and being overconfident in…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Luís Almeida , Inês Dutra , Francesco Renna

This paper introduces the first gradient-based framework for prompt optimization in text-to-image diffusion models. We formulate prompt engineering as a discrete optimization problem over the language space. Two major challenges arise in…

Machine Learning · Computer Science 2024-07-03 Ruochen Wang , Ting Liu , Cho-Jui Hsieh , Boqing Gong

Localizing object parts precisely is essential for tasks such as object recognition and robotic manipulation. Recent part segmentation methods require extensive training data and labor-intensive annotations. Segment-Anything Model (SAM) has…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 S. B. van Rooij , G. J. Burghouts

Large Vision-Language Models (VLMs) are increasingly being regarded as foundation models that can be instructed to solve diverse tasks by prompting, without task-specific training. We examine the seemingly obvious question: how to…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Niccolo Avogaro , Thomas Frick , Mattia Rigotti , Andrea Bartezzaghi , Filip Janicki , Cristiano Malossi , Konrad Schindler , Roy Assaf

The universal model emerges as a promising trend for medical image segmentation, paving up the way to build medical imaging large model (MILM). One popular strategy to build universal models is to encode each task as a one-hot vector and…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Yiwen Ye , Yutong Xie , Jianpeng Zhang , Ziyang Chen , Yong Xia

With the advancement of large pre-trained vision-language models, effectively transferring the knowledge embedded within these foundational models to downstream tasks has become a pivotal topic, particularly in data-scarce environments.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-12 Tianxiang Hao , Mengyao Lyu , Hui Chen , Sicheng Zhao , Xiaohan Ding , Jungong Han , Guiguang Ding

Prompt learning has emerged as a promising paradigm for adapting pre-trained vision-language models (VLMs) to few-shot whole slide image (WSI) classification by aligning visual features with textual representations, thereby reducing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Junjie Zhou , Wei Shao , Yagao Yue , Wei Mu , Peng Wan , Qi Zhu , Daoqiang Zhang

Task-generic promptable image segmentation aims to achieve segmentation of diverse samples under a single task description by utilizing only one task-generic prompt. Current methods leverage the generalization capabilities of…

Computer Vision and Pattern Recognition · Computer Science 2025-02-03 Jian Hu , Zixu Cheng , Shaogang Gong

This paper investigates the fundamental discontinuity between the latest two Segment Anything Models: SAM2 and SAM3. We explain why the expertise in prompt-based segmentation of SAM2 does not transfer to the multimodal concept-driven…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Ranjan Sapkota , Konstantinos I. Roumeliotis , Manoj Karkee

Segment Anything Model 2 (SAM 2), a prompt-driven foundation model extending SAM to both image and video domains, has shown superior zero-shot performance compared to its predecessor. Building on SAM's success in medical image segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-06 Bin Xie , Hao Tang , Yan Yan , Gady Agam

Multi-rater medical image segmentation captures the inherent ambiguity of clinical interpretation, where diagnostic boundaries vary across experts and imaging devices. Existing approaches often reduce this diversity to consensus labels or…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Sanaz Karimijafarbigloo , Armin Khosravi , Alireza Kheyrkhah , Reza Azad , Mauricio Reyes , Dorit Merhof

Semantic segmentation of microscopic cell images using deep learning is an important technique, however, it requires a large number of images and ground truth labels for training. To address the above problem, we consider an efficient…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Sota Kato , Kazuhiro Hotta

Nuclei instance segmentation in pathological images is crucial for downstream tasks such as tumor microenvironment analysis. However, the high cost and scarcity of annotated data limit the applicability of fully supervised methods, while…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Zenan Lin , Wei Li , Jintao Chen , Zihao Wu , Wenxiong Kang , Changxin Gao , Liansheng Wang , Jin-Gang Yu

Going beyond mere fine-tuning of vision-language models (VLMs), learnable prompt tuning has emerged as a promising, resource-efficient alternative. Despite their potential, effectively learning prompts faces the following challenges: (i)…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Hari Chandana Kuchibhotla , Sai Srinivas Kancheti , Abbavaram Gowtham Reddy , Vineeth N Balasubramanian

Prompt-driven vision foundation models, such as the Segment Anything Model, have recently demonstrated remarkable adaptability in computer vision. However, their direct application to medical imaging remains challenging due to heterogeneous…

Image and Video Processing · Electrical Eng. & Systems 2025-11-14 Himashi Peiris , Sizhe Wang , Gary Egan , Mehrtash Harandi , Meng Law , Zhaolin Chen

Domain generalization is critical in computational pathology (CPath) due to inherent domain shifts caused by variations in staining protocols, scanner devices, and imaging settings across clinical centers. Vision-language models (VLMs),…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Amir Mohammad Ezzati , Alireza Malekhosseini , Armin Khosravi , Mohammad Hossein Rohban

The remarkable capabilities of the Segment Anything Model (SAM) for tackling image segmentation tasks in an intuitive and interactive manner has sparked interest in the design of effective visual prompts. Such interest has led to the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Jorge Quesada , Zoe Fowler , Mohammad Alotaibi , Mohit Prabhushankar , Ghassan AlRegib

In text-to-image generation tasks, the advancements of diffusion models have facilitated the fidelity of generated results. However, these models encounter challenges when processing text prompts containing multiple entities and attributes.…

Computation and Language · Computer Science 2024-04-23 Yihang Wu , Xiao Cao , Kaixin Li , Zitan Chen , Haonan Wang , Lei Meng , Zhiyong Huang

Medical image segmentation is fundamental to clinical decision-making, yet existing models remain fragmented. They are usually trained on single knowledge sources and specific to individual tasks, modalities, or organs. This fragmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Bangwei Guo , Yunhe Gao , Meng Ye , Difei Gu , Yang Zhou , Leon Axel , Dimitris Metaxas

The Segment Anything Model (SAM) has revolutionized image segmentation through its innovative prompt-based approach, yet the critical role of prompt engineering in its success remains underexplored. This paper presents the first…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Yidong Jiang
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