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New lesion segmentation is essential to estimate the disease progression and therapeutic effects during multiple sclerosis (MS) clinical treatments. However, the expensive data acquisition and expert annotation restrict the feasibility of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-18 Yicheng Wu , Zhonghua Wu , Hengcan Shi , Bjoern Picker , Winston Chong , Jianfei Cai

Medical image segmentation is evolving from task-specific models toward generalizable frameworks. Recent research leverages Multi-modal Large Language Models (MLLMs) as autonomous agents, employing reinforcement learning with verifiable…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Shengyuan Liu , Liuxin Bao , Qi Yang , Wanting Geng , Boyun Zheng , Chenxin Li , Wenting Chen , Houwen Peng , Yixuan Yuan

Composed Image Retrieval (CIR) aims to retrieve target images based on a reference image and modified texts. However, existing methods often struggle to extract the correct semantic cues from the reference image that best reflect the user's…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Xuri Ge , Chunhao Wang , Xindi Wang , Zheyun Qin , Zhumin Chen , Xin Xin

Federated learning (FL) has been widely employed for medical image analysis to facilitate multi-client collaborative learning without sharing raw data. Despite great success, FL's performance is limited for multiple sclerosis (MS) lesion…

Accurately segmenting different organs from medical images is a critical prerequisite for computer-assisted diagnosis and intervention planning. This study proposes a deep learning-based approach for segmenting various organs from CT and…

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Vision-Language Models (VLMs) excel at many multimodal tasks, yet they frequently struggle with tasks requiring precise understanding and handling of fine-grained visual elements. This is mainly due to information loss during image encoding…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Xuchen Li , Xuzhao Li , Jiahui Gao , Renjie Pi , Shiyu Hu , Wentao Zhang

Representation learning offers a conduit to elucidate distinctive features within the latent space and interpret the deep models. However, the randomness of lesion distribution and the complexity of low-quality factors in medical images…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Qingshan Hou , Shuai Cheng , Peng Cao , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane , Yih Chung Tham

Large language models (LLMs) show significant potential for clinical decision support (CDS), yet their black-box nature -- characterized by untraceable reasoning and probabilistic hallucinations -- poses severe challenges in acupuncture, a…

Artificial Intelligence · Computer Science 2026-03-10 Liuyi Xu , Yun Guo , Ming Chen , Zihan Dun , Yining Qian , An-Yang Lu , Shuang Li , Lijun Liu

Multimodal Large Language Models (MLLMs) perform well in single-image visual grounding but struggle with real-world tasks that demand cross-image reasoning and multi-modal instructions. To address this, we adopt a reinforcement learning…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Bob Zhang , Haoran Li , Tao Zhang , Jianan Li , Cilin Yan , Xikai Liu , Jiayin Cai , Yanbin Hao

Lesion segmentation is an important problem in computer-assisted diagnosis that remains challenging due to the prevalence of low contrast, irregular boundaries that are unamenable to shape priors. We introduce Deep Active Lesion…

Image and Video Processing · Electrical Eng. & Systems 2020-09-01 Ali Hatamizadeh , Assaf Hoogi , Debleena Sengupta , Wuyue Lu , Brian Wilcox , Daniel Rubin , Demetri Terzopoulos

Referring segmentation grounds natural-language queries to pixel-level masks, but extending it to complex scenarios with multiple instances, cross-category groups, or open-ended target sets remains challenging. Previous Large Vision…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Zhixiong Zhang , Yizhuo Li , Shuangrui Ding , Yuhang Zang , Shengyuan Ding , Long Xing , Yibin Wang , Qiaosheng Zhang , Jiaqi Wang

Accurate segmentation of lesions plays a critical role in medical image analysis and diagnosis. Traditional segmentation approaches that rely solely on visual features often struggle with the inherent uncertainty in lesion distribution and…

Image and Video Processing · Electrical Eng. & Systems 2025-04-03 Dandan Shan , Zihan Li , Yunxiang Li , Qingde Li , Jie Tian , Qingqi Hong

Medical image segmentation plays a vital role in clinical decision-making, enabling precise localization of lesions and guiding interventions. Despite significant advances in segmentation accuracy, the black-box nature of most deep models…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Limai Jiang , Ruitao Xie , Bokai Yang , Huazhen Huang , Juan He , Yufu Huo , Zikai Wang , Yang Wei , Yunpeng Cai

Referring medical image segmentation targets delineating lesions indicated by textual descriptions. Aligning visual and textual cues is challenging due to their distinct data properties. Inspired by large-scale pre-trained vision-language…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Yaxiong Chen , Minghong Wei , Zixuan Zheng , Jingliang Hu , Yilei Shi , Shengwu Xiong , Xiao Xiang Zhu , Lichao Mou

Referring Expression Comprehension (REC) is a foundational cross-modal task that evaluates the interplay of language understanding, image comprehension, and language-to-image grounding. It serves as an essential testing ground for…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Xuzheng Yang , Junzhuo Liu , Peng Wang , Guoqing Wang , Yang Yang , Heng Tao Shen

Recently, segmentation methods based on Convolutional Neural Networks (CNNs) showed promising performance in automatic Multiple Sclerosis (MS) lesions segmentation. These techniques have even outperformed human experts in controlled…

Image and Video Processing · Electrical Eng. & Systems 2021-07-26 Reda Abdellah Kamraoui , Vinh-Thong Ta , Thomas Tourdias , Boris Mansencal , José V Manjon , Pierrick Coupé

Semantic segmentation of brain tumours is a fundamental task in medical image analysis that can help clinicians in diagnosing the patient and tracking the progression of any malignant entities. Accurate segmentation of brain lesions is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Aditya Kasliwal , Sankarshanaa Sagaram , Laven Srivastava , Pratinav Seth , Adil Khan

Multimodal Large Language Models (MLLMs) have achieved remarkable success in open-vocabulary perceptual tasks, yet their ability to solve complex cognitive problems remains limited, especially when visual details are abstract and require…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Boyi Li , Yifan Shen , Yuanzhe Liu , Yifan Xu , Jiateng Liu , Xinzhuo Li , Zhengyuan Li , Jingyuan Zhu , Yunhan Zhong , Fangzhou Lan , Jianguo Cao , James M. Rehg , Heng Ji , Ismini Lourentzou , Xu Cao

Segmentation has been a major task in neuroimaging. A large number of automated methods have been developed for segmenting healthy and diseased brain tissues. In recent years, deep learning techniques have attracted a lot of attention as a…

Image and Video Processing · Electrical Eng. & Systems 2019-07-05 Jimit Doshi , Guray Erus , Mohamad Habes , Christos Davatzikos
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