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We propose a segmentation framework that uses deep neural networks and introduce two innovations. First, we describe a biophysics-based domain adaptation method. Second, we propose an automatic method to segment white and gray matter, and…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Amir Gholami , Shashank Subramanian , Varun Shenoy , Naveen Himthani , Xiangyu Yue , Sicheng Zhao , Peter Jin , George Biros , Kurt Keutzer

Semantic segmentation is a powerful method to facilitate visual scene understanding. Each pixel is assigned a label according to a pre-defined list of object classes and semantic entities. This becomes very useful as a means to summarize…

Computer Vision and Pattern Recognition · Computer Science 2018-11-21 Marc Bosch , Gordon A. Christie , Christopher M. Gifford

Semantic segmentation, a key task in computer vision with broad applications in autonomous driving, medical imaging, and robotics, has advanced substantially with deep learning. Nevertheless, current approaches remain vulnerable to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Iacopo Curti , Pierluigi Zama Ramirez , Alioscia Petrelli , Luigi Di Stefano

Deep learning models have become the dominant method for medical image segmentation. However, they often struggle to be generalisable to unknown tasks involving new anatomical structures, labels, or shapes. In these cases, the model needs…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Jing Xu

Medical Image Segmentation is a useful application for medical image analysis including detecting diseases and abnormalities in imaging modalities such as MRI, CT etc. Deep learning has proven to be promising for this task but usually has a…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Soham Bhosale , Arjun Krishna , Ge Wang , Klaus Mueller

Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

Convolutional neural network (CNN), in particular the Unet, is a powerful method for medical image segmentation. To date Unet has demonstrated state-of-art performance in many complex medical image segmentation tasks, especially under the…

Image and Video Processing · Electrical Eng. & Systems 2019-10-31 Wenjun Yan , Yuanyuan Wang , Shengjia Gu , Lu Huang , Fuhua Yan , Liming Xia , Qian Tao

Foundation medical segmentation models, with MedSAM being the most popular, have achieved promising performance across organs and lesions. However, MedSAM still suffers from compromised performance on specific lesions with intricate…

Quantitative Methods · Quantitative Biology 2025-07-16 Kecheng Chen , Xinyu Luo , Tiexin Qin , Jie Liu , Hui Liu , Victor Ho Fun Lee , Hong Yan , Haoliang Li

The emergence of large models, also known as foundation models, has brought significant advancements to AI research. One such model is Segment Anything (SAM), which is designed for image segmentation tasks. However, as with other foundation…

Computer Vision and Pattern Recognition · Computer Science 2023-05-03 Tianrun Chen , Lanyun Zhu , Chaotao Ding , Runlong Cao , Yan Wang , Zejian Li , Lingyun Sun , Papa Mao , Ying Zang

Recent text-to-image (T2I) models have made remarkable progress in generating visually realistic and semantically coherent images. However, they still suffer from randomness and inconsistency with the given prompts, particularly when…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Kaishen Wang , Ruibo Chen , Tong Zheng , Heng Huang

Medical image segmentation remains challenging in low-data regimes, where scarce annotations often yield poor generalization and ambiguous boundaries with missing fine structures. Recent self-supervised pretraining has improved…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Zhiquan Chen , Haitao Wang , Guowei Zou , Hejun Wu

We propose a straightforward yet highly effective few-shot fine-tuning strategy for adapting the Segment Anything (SAM) to anatomical segmentation tasks in medical images. Our novel approach revolves around reformulating the mask decoder…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Weiyi Xie , Nathalie Willems , Shubham Patil , Yang Li , Mayank Kumar

Medical image segmentation models are typically optimised with voxel-wise losses that constrain predictions only in the output space. This leaves latent feature representations largely unconstrained, potentially limiting generalisation. We…

Image and Video Processing · Electrical Eng. & Systems 2026-03-02 Puru Vaish , Amin Ranem , Felix Meister , Tobias Heimann , Christoph Brune , Jelmer M. Wolterink

Over the past decade, Deep Convolutional Neural Networks have been widely adopted for medical image segmentation and shown to achieve adequate performance. However, due to the inherent inductive biases present in the convolutional…

Computer Vision and Pattern Recognition · Computer Science 2021-07-08 Jeya Maria Jose Valanarasu , Poojan Oza , Ilker Hacihaliloglu , Vishal M. Patel

The development of high-resolution remote sensing satellites has provided great convenience for research work related to remote sensing. Segmentation and extraction of specific targets are essential tasks when facing the vast and complex…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Jie Zhang , Xubing Yang , Rui Jiang , Wei Shao , Li Zhang

The purpose of federated learning is to enable multiple clients to jointly train a machine learning model without sharing data. However, the existing methods for training an image segmentation model have been based on an unrealistic…

Computer Vision and Pattern Recognition · Computer Science 2022-05-05 Jeffry Wicaksana , Zengqiang Yan , Dong Zhang , Xijie Huang , Huimin Wu , Xin Yang , Kwang-Ting Cheng

The intricate morphology of brain vessels poses significant challenges for automatic segmentation models, which usually focus on a single imaging modality. However, accurately treating brain-related conditions requires a comprehensive…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Francesco Galati , Daniele Falcetta , Rosa Cortese , Ferran Prados , Ninon Burgos , Maria A. Zuluaga

Accurate automatic medical image segmentation relies on high-quality, dense annotations, which are costly and time-consuming. Weakly supervised learning provides a more efficient alternative by leveraging sparse and coarse annotations…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Dongdong Meng , Sheng Li , Hao Wu , Suqing Tian , Wenjun Ma , Guoping Wang , Xueqing Yan

Medical image segmentation is vital to the area of medical imaging because it enables professionals to more accurately examine and understand the information offered by different imaging modalities. The technique of splitting a medical…

Image and Video Processing · Electrical Eng. & Systems 2024-09-01 Aitik Gupta , Joydip Dhar

Image segmentation is a critical task in microscopy, essential for accurately analyzing and interpreting complex visual data. This task can be performed using custom models trained on domain-specific datasets, transfer learning from…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Kamyar Barakati , Utkarsh Pratiush , Sheryl L. Sanchez , Aditya Raghavan , Delia J. Milliron , Mahshid Ahmadi , Philip D. Rack , Sergei V. Kalinin
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