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Chain-of-Thought (CoT) reasoning has proven effective in enhancing large language models by encouraging step-by-step intermediate reasoning, and recent advances have extended this paradigm to Multimodal Large Language Models (MLLMs). In the…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Juntao Jiang , Jiangning Zhang , Yali Bi , Jinsheng Bai , Weixuan Liu , Weiwei Jin , Zhucun Xue , Yong Liu , Xiaobin Hu , Shuicheng Yan

Chest X-ray imaging is crucial for diagnosing pulmonary and cardiac diseases, yet its interpretation demands extensive clinical experience and suffers from inter-observer variability. While deep learning models offer high diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Chee Ng , Liliang Sun , Shaoqing Tang

Chain-of-thought (CoT) reasoning has advanced medical visual question answering (VQA), yet most existing CoT rationales are free-form and fail to capture the structured reasoning process clinicians actually follow. This work asks: Can…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Lin Fan , Yafei Ou , Zhipeng Deng , Pengyu Dai , Hou Chongxian , Jiale Yan , Yaqian Li , Kaiwen Long , Xun Gong , Masayuki Ikebe , Yefeng Zheng

Chain-of-Thought (CoT) reasoning has proven effective in natural language tasks but remains underexplored in multimodal alignment. This study investigates its integration into 3D vision-language learning by embedding structured reasoning…

Computation and Language · Computer Science 2025-03-18 Yanjun Chen , Yirong Sun , Xinghao Chen , Jian Wang , Xiaoyu Shen , Wenjie Li , Wei Zhang

Artificial intelligence has advanced in Medical Visual Question Answering (Med-VQA), but prevalent research tends to focus on the accuracy of the answers, often overlooking the reasoning paths and interpretability, which are crucial in…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Jiaxiang Liu , Yuan Wang , Jiawei Du , Joey Tianyi Zhou , Zuozhu Liu

Chain-of-thought (CoT) reasoning is fundamental to modern LLM architectures and represents a critical intervention point for AI safety. However, CoT reasoning may exhibit failure modes that we note as pathologies, which prevent it from…

Artificial Intelligence · Computer Science 2026-02-17 Manqing Liu , David Williams-King , Ida Caspary , Linh Le , Hannes Whittingham , Puria Radmard , Cameron Tice , Edward James Young

By extending the advantage of chain-of-thought (CoT) reasoning in human-like step-by-step processes to multimodal contexts, multimodal CoT (MCoT) reasoning has recently garnered significant research attention, especially in the integration…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Yaoting Wang , Shengqiong Wu , Yuecheng Zhang , Shuicheng Yan , Ziwei Liu , Jiebo Luo , Hao Fei

Faithful reasoning in medical vision-language models (VLMs) requires not only accurate predictions but also transparent alignment between textual rationales and visual evidence. While Chain-of-Thought (CoT) prompting has shown promise in…

Chain-of-Thought (CoT) has widely enhanced mathematical reasoning in Large Language Models (LLMs), but it still remains challenging for extending it to multimodal domains. Existing works either adopt a similar textual reasoning for image…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Xinyan Chen , Renrui Zhang , Dongzhi Jiang , Aojun Zhou , Shilin Yan , Weifeng Lin , Hongsheng Li

The ability to perform Chain-of-Thought (CoT) reasoning marks a major milestone for multimodal models (MMs), enabling them to solve complex visual reasoning problems. Yet a critical question remains: is such reasoning genuinely grounded in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-10 Jusheng Zhang , Kaitong Cai , Xiaoyang Guo , Sidi Liu , Qinhan Lv , Ruiqi Chen , Jing Yang , Yijia Fan , Xiaofei Sun , Jian Wang , Ziliang Chen , Liang Lin , Keze Wang

With the remarkable success of Multimodal Large Language Models (MLLMs) in perception tasks, enhancing their complex reasoning capabilities has emerged as a critical research focus. Existing models still suffer from challenges such as…

Computation and Language · Computer Science 2025-12-01 Wenxin Zhu , Andong Chen , Yuchen Song , Kehai Chen , Conghui Zhu , Ziyan Chen , Tiejun Zhao

Vision-language models (VLMs) have shown strong promise for medical image analysis, but most remain opaque, offering predictions without the transparent, stepwise reasoning clinicians rely on. We present a framework that brings…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Andriy Myronenko , Dong Yang , Baris Turkbey , Mariam Aboian , Sena Azamat , Esra Akcicek , Hongxu Yin , Pavlo Molchanov , Marc Edgar , Yufan He , Pengfei Guo , Yucheng Tang , Daguang Xu

Chain of Thought (CoT) reasoning has demonstrated remarkable deep reasoning capabilities in both large language models (LLMs) and multimodal large language models (MLLMs). However, its reliability is often undermined by the accumulation of…

Artificial Intelligence · Computer Science 2025-11-26 Zijun Chen , Wenbo Hu , Richang Hong

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

Chain-of-Thought (CoT) prompting helps models think step by step. But naive CoT breaks down in visually grounded social tasks, where models must perceive, understand, and judge all at once; bridging perception with norm-grounded reasoning.…

Computation and Language · Computer Science 2026-04-21 Eunkyu Park , Wesley Hanwen Deng , Gunhee Kim , Motahhare Eslami , Maarten Sap

Cancer screening is a reasoning task. A radiologist observes findings, compares them to prior scans, integrates clinical context, and reaches a diagnostic conclusion confirmed by pathology. We present RadThinking, a Visual Question…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Wenxuan Li , Pedro R. A. S. Bassi , Xinze Zhou , Jakob Wasserthal , Alan L. Yuille , Zongwei Zhou

Medical vision-language models (VLMs) and AI agents have made significant progress in learning to analyze and reason about clinical images. However, existing medical visual question answering (VQA) benchmarks collapse model capabilities…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yixiong Chen , Wenjie Xiao , Pedro R. A. S. Bassi , Boyan Wang , Liang He , Xinze Zhou , Sezgin Er , Ibrahim Ethem Hamamci , Zongwei Zhou , Alan Yuille

Large language models (LLMs) have shown impressive performance on complex reasoning by leveraging chain-of-thought (CoT) prompting to generate intermediate reasoning chains as the rationale to infer the answer. However, existing CoT studies…

Computation and Language · Computer Science 2024-05-21 Zhuosheng Zhang , Aston Zhang , Mu Li , Hai Zhao , George Karypis , Alex Smola

While Chain-of-Thought (CoT) prompting has significantly advanced the reasoning capabilities of Multimodal Large Language Models (MLLMs), relying solely on linear text sequences remains a bottleneck for complex tasks. We observe that even…

Computation and Language · Computer Science 2026-02-12 Lingzhuang Sun , Yuxia Zhu , Ruitong Liu , Hao Liang , Zheng Sun , Caijun Jia , Honghao He , Yuchen Wu , Siyuan Li , Jingxuan Wei , Xiangxiang Zhang , Bihui Yu , Wentao Zhang

Medical Vision-Language Models have shown promising potential in clinical decision support, yet they remain prone to factual hallucinations due to insufficient grounding in localized pathological evidence. Existing medical alignment methods…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Xiwei Liu , Yulong Li , Xinlin Zhuang , Xuhui Li , Jianxu Chen , Haolin Yang , Imran Razzak , Yutong Xie
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