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The pre-trained transformer demonstrates remarkable generalization ability in natural image processing. However, directly transferring it to magnetic resonance images faces two key challenges: the inability to adapt to the specificity of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Jingkai Li , Xiaoze Tian , Yuhang Shen , Jia Wang , Dianjie Lu , Guijuan Zhang , Zhuoran Zheng

Inverse problems, such as accelerated MRI reconstruction, are ill-posed and an infinite amount of possible and plausible solutions exist. This may not only lead to uncertainty in the reconstructed image but also in downstream tasks such as…

Image and Video Processing · Electrical Eng. & Systems 2024-07-26 Jan Nikolas Morshuis , Matthias Hein , Christian F. Baumgartner

Magnetic Resonance Imaging (MRI) is an inherently multi-contrast modality, where cross-contrast priors can be exploited to improve image reconstruction from undersampled data. Recently, diffusion models have shown remarkable performance in…

Image and Video Processing · Electrical Eng. & Systems 2025-10-27 Yue Wang , Yuanbiao Yang , Zhuo-xu Cui , Tian Zhou , Bingsheng Huang , Hairong Zheng , Dong Liang , Yanjie Zhu

Perfusion-weighted magnetic resonance imaging (MRI) is an imaging technique that allows one to measure tissue perfusion in an organ of interest through the injection of an intravascular paramagnetic contrast agent (CA). Due to a preference…

Computer Vision and Pattern Recognition · Computer Science 2017-08-28 Cagdas Ulas , Christine Preibisch , Jonathan Sperl , Thomas Pyka , Jayashree Kalpathy-Cramer , Bjoern Menze

Diffusion models have established new state of the art in a multitude of computer vision tasks, including image restoration. Diffusion-based inverse problem solvers generate reconstructions of exceptional visual quality from heavily…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Zalan Fabian , Berk Tinaz , Mahdi Soltanolkotabi

Estimating intra- and extra-axonal microstructure parameters, such as volume fractions and diffusivities, has been one of the major efforts in brain microstructure imaging with MRI. The Standard Model (SM) of diffusion in white matter has…

Diffusion models have recently gained popularity for accelerated MRI reconstruction due to their high sample quality. They can effectively serve as rich data priors while incorporating the forward model flexibly at inference time, and they…

Image and Video Processing · Electrical Eng. & Systems 2023-10-20 Batu Ozturkler , Chao Liu , Benjamin Eckart , Morteza Mardani , Jiaming Song , Jan Kautz

Diffusion MRI (dMRI) provides a distinctive means to probe the microstructural architecture of living tissue, facilitating applications such as brain connectivity analysis, modeling across multiple conditions, and the estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Jongyeon Yoon , Elyssa M. McMaster , Michael E. Kim , Gaurav Rudravaram , Kurt G. Schilling , Bennett A. Landman , Daniel Moyer

Water diffusion gives rise to micron-scale sensitivity of diffusion MRI (dMRI) to cellular-level tissue structure. Precision medicine and quantitative imaging depend on uncovering the information content of dMRI and establishing its…

Medical Physics · Physics 2026-02-03 Santiago Coelho , Jenny Chen , Filip Szczepankiewicz , Els Fieremans , Dmitry S. Novikov

Diffusion model-based approaches recently achieved re-markable success in MRI reconstruction, but integration into clinical routine remains challenging due to its time-consuming convergence. This phenomenon is partic-ularly notable when…

Image and Video Processing · Electrical Eng. & Systems 2024-11-07 Yu Guan , Qinrong Cai , Wei Li , Qiuyun Fan , Dong Liang , Qiegen Liu

Diffusion-weighted magnetic resonance imaging (DW-MRI) is used to characterize brain tissue microstructure employing tissue-specific biophysical models. A current limitation, however, is that most of the proposed models are based on the…

Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 William Consagra , Lipeng Ning , Yogesh Rathi

Diffusion MRI microstructure fitting is nonconvex and often performed voxelwise, which limits fiber peak recovery in narrow crossings. This work introduces PRISM, a differentiable analysis-by-synthesis framework that fits an explicit…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Mohamed Abouagour , Atharva Shah , Eleftherios Garyfallidis

Pseudo-healthy image inpainting is an essential preprocessing step for analyzing pathological brain MRI scans. Most current inpainting methods favor slice-wise 2D models for their high in-plane fidelity, but their independence across slices…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Dou Hoon Kwark , Shirui Luo , Xiyue Zhu , Yudu Li , Zhi-Pei Liang , Volodymyr Kindratenko

Incoherent k-space undersampling and deep learning-based reconstruction methods have shown great success in accelerating MRI. However, the performance of most previous methods will degrade dramatically under high acceleration factors, e.g.,…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Jin Liu , Qing Lin , Zhuang Xiong , Shanshan Shan , Chunyi Liu , Min Li , Feng Liu , G. Bruce Pike , Hongfu Sun , Yang Gao

Diffusion-weighted MRI is the forerunner of the rapidly developed microstructural MRI aimed at in vivo evaluation of the cellular tissue architecture. This brief review focuses on the spatiotemporal scales of the microstructure that are…

Medical Physics · Physics 2020-08-14 Valerij G. Kiselev

Diffusion Magnetic Resonance Imaging (dMRI) is an imaging technique with exquisite sensitivity to the microstructural properties of heterogeneous media. The conventionally adopted acquisition schemes involving single pulsed field gradients…

Biological Physics · Physics 2023-01-04 Deneb Boito , Cem Yolcu , Evren Özarslan

Ill-posed imaging inverse problems remain challenging due to the ambiguity in mapping degraded observations to clean images. Diffusion-based generative priors have recently shown promise, but typically rely on computationally intensive…

Image and Video Processing · Electrical Eng. & Systems 2026-02-13 Ayush Varshney , Katherine L. Bouman , Berthy T. Feng

Diffusion-weighted imaging (DWI) is a type of Magnetic Resonance Imaging (MRI) technique sensitised to the diffusivity of water molecules, offering the capability to inspect tissue microstructures and is the only in-vivo method to…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Sheng Chen , Zihao Tang , Mariano Cabezas , Xinyi Wang , Arkiev D'Souza , Michael Barnett , Fernando Calamante , Weidong Cai , Chenyu Wang

Diffusion MRI (dMRI) provides the ability to reconstruct neuronal fibers in the brain, $\textit{in vivo}$, by measuring water diffusion along angular gradient directions in q-space. High angular resolution diffusion imaging (HARDI) can…

Machine Learning · Statistics 2018-05-30 Evan Schwab , René Vidal , Nicolas Charon