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In recent years, Artificial Intelligence has become a powerful partner for complex tasks such as data analysis, prediction, and problem-solving, yet its lack of transparency raises concerns about its reliability. In sensitive domains such…

Machine Learning · Computer Science 2026-03-10 Jesús Sánchez Ochoa , Enrique Tomás Martínez Beltrán , Alberto Huertas Celdrán

Background: Current neuronal monitoring techniques, such as calcium imaging and multi-electrode arrays, enable recordings of spiking activity from hundreds of neurons simultaneously. Of primary importance in systems neuroscience is the…

Neurons and Cognition · Quantitative Biology 2014-11-11 Yazan N. Billeh , Michael T. Schaub , Costas A. Anastassiou , Mauricio Barahona , Christof Koch

Predicting how a dynamical unit evolves over time - how an individual ages, an epidemic spreads, or a physical system degrades - typically requires dense longitudinal tracking. When only extremely sparse or entirely cross-sectional data is…

Machine Learning · Computer Science 2026-05-25 Christian Lagemann , Kai Lagemann , Steven L. Brunton , Sach Mukherjee

The epileptic mechanism is postulated as that an animal's neurons gradually diminish their inhibition function coupled with enhanced excitation when an epileptic event is approaching. Calcium imaging technique is designed to directly record…

Neurons and Cognition · Quantitative Biology 2018-03-13 Jingyi Zheng , Fushing Hsieh

Inferring the directionality of interactions between cellular processes is a major challenge in systems biology. Time-lagged correlations allow to discriminate between alternative models, but they still rely on assumed underlying…

Quantitative Methods · Quantitative Biology 2017-11-15 Sourabh Lahiri , Philippe Nghe , Sander J. Tans , Martin Luc Rosinberg , David Lacoste

We introduce and study methods for inferring and learning from correspondences among neurons. The approach enables alignment of data from distinct multiunit studies of nervous systems. We show that the methods for inferring correspondences…

Neurons and Cognition · Quantitative Biology 2015-01-28 Ashish Kapoor , E. Paxon Frady , Stefanie Jegelka , William B. Kristan , Eric Horvitz

In recommendation systems, users frequently engage in multiple types of behaviors, such as clicking, adding to a cart, and purchasing. However, with diversified behavior data, user behavior sequences will become very long in the short term,…

Information Retrieval · Computer Science 2024-03-27 Yongqiang Han , Hao Wang , Kefan Wang , Likang Wu , Zhi Li , Wei Guo , Yong Liu , Defu Lian , Enhong Chen

Recent technological advances have enabled the recording of neurons in intact circuits with a high spatial and temporal resolution, creating the need for modeling with the same precision. In particular, the development of ultra-fast…

Neurons and Cognition · Quantitative Biology 2023-11-30 Claire Guerrier , Tristan Dellazizzo Toth , Nicolas Galtier , Kurt Haas

Fluorescence is a powerful mean to probe information processing in the mammalian brain. However, neuronal tissues are highly heterogeneous and thus opaque to light. A wide set of non-invasive or invasive techniques for scattered light…

Optics · Physics 2020-05-11 Claudio Moretti , Sylvain Gigan

Change detection aims to identify remote sense object changes by analyzing data between bitemporal image pairs. Due to the large temporal and spatial span of data collection in change detection image pairs, there are often a significant…

Computer Vision and Pattern Recognition · Computer Science 2024-06-24 Qiangang Du , Jinlong Peng , Changan Wang , Xu Chen , Qingdong He , Wenbing Zhu , Mingmin Chi , Yabiao Wang , Chengjie Wang

Decoding behavior, such as movement, from multiscale brain networks remains a central objective in neuroscience. Over the past decades, artificial intelligence and machine learning have played an increasingly significant role in elucidating…

Neurons and Cognition · Quantitative Biology 2025-04-24 Ghazal Mirzaee , Jonathan Chang , Shahrzad Latifi

In this paper we present a simple microscopic stochastic model describing short term plasticity within a large homogeneous network of interacting neurons. Each neuron is represented by its membrane potential and by the residual calcium…

Probability · Mathematics 2020-01-29 Antonio Galves , Eva Löcherbach , Christophe Pouzat , Errico Presutti

The nervous system encodes continuous information from the environment in the form of discrete spikes, and then decodes these to produce smooth motor actions. Understanding how spikes integrate, represent, and process information to produce…

Neural and Evolutionary Computing · Computer Science 2017-11-15 Madhavun Candadai Vasu , Eduardo Izquierdo

Continual learning (CL) aims to learn new tasks while retaining past knowledge, addressing the challenge of forgetting during task adaptation. Rehearsal-based methods, which replay previous samples, effectively mitigate forgetting. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Ruiqi Liu , Boyu Diao , Libo Huang , Hangda Liu , Chuanguang Yang , Zhulin An , Yongjun Xu

This paper reports on the use of a convolutional neural network (CNN) methodology to analyse fluorescence images of calcium-ion Coulomb crystals in the gas phase. A transfer-learning approach is adopted using the publicly available RESNET50…

Using miniscope recordings of calcium fluorescence signals in the CA1 region of the hippocampus of mice, we monitor the neural activity of hippocampal regions while the animals are freely moving in an open chamber. Using a data-driven…

Neurons and Cognition · Quantitative Biology 2022-04-06 Yi-Ling Chen , Chun-Chung Chen , Yu-Ying Mei , Ning Zhou , Dongchuan Wu , Ting-Kuo Lee

The recent development of genetically encoded calcium indicators enables monitoring in vivo the activity of neuronal populations. Most analysis of these calcium transients relies on linear regression analysis based on the sensory stimulus…

Neurons and Cognition · Quantitative Biology 2014-09-10 Fabrizio De Vico Fallani , Martina Corazzol , Jenna R. Sternberg , Claire Wyart , Mario Chavez

Semantic segmentation of outdoor scenes is problematic when there are variations in imaging conditions. It is known that albedo (reflectance) is invariant to all kinds of illumination effects. Thus, using reflectance images for semantic…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Anil S. Baslamisli , Thomas T. Groenestege , Partha Das , Hoang-An Le , Sezer Karaoglu , Theo Gevers

Advances in intensity-based microscopy techniques have improved our ability to quantify particle motion at microscopic scales, enabling insight into diffusion and collective dynamics. Building on this foundation, we introduce a novel…

Soft Condensed Matter · Physics 2026-04-03 Sophie Hermann , Seyed Saman Banarooei , Adam Carter , Carlos A. Silvera Batista , Sophie Marbach

Modern neural recording techniques such as two-photon imaging or Neuropixel probes allow to acquire vast time-series datasets with responses of hundreds or thousands of neurons. Contrastive learning is a powerful self-supervised framework…

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