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Understanding the reliability of natural language generation is critical for deploying foundation models in security-sensitive domains. While certified poisoning defenses provide provable robustness bounds for classification tasks, they are…

Machine Learning · Computer Science 2026-02-11 Mihnea Ghitu , Matthew Wicker

Large Language Models (LLMs) have the potential to accelerate small molecule drug design due to their ability to reason about information from diverse sources and formats. However, their practical utility remains unclear due to the lack of…

Domain alignment (DA) has been widely used in unsupervised domain adaptation. Many existing DA methods assume that a low source risk, together with the alignment of distributions of source and target, means a low target risk. In this paper,…

Machine Learning · Computer Science 2020-06-12 Yueming Yin , Zhen Yang , Haifeng Hu , Xiaofu Wu

Adapting pre-trained language models (PrLMs) (e.g., BERT) to new domains has gained much attention recently. Instead of fine-tuning PrLMs as done in most previous work, we investigate how to adapt the features of PrLMs to new domains…

Computation and Language · Computer Science 2020-12-01 Hai Ye , Qingyu Tan , Ruidan He , Juntao Li , Hwee Tou Ng , Lidong Bing

Log Anomaly Detection (LAD) seeks to identify atypical patterns in log data that are crucial to assessing the security and condition of systems. Although Large Language Models (LLMs) have shown tremendous success in various fields, the use…

Machine Learning · Computer Science 2025-03-12 Ying Fu Lim , Jiawen Zhu , Guansong Pang

Aligning large language models (LLMs) with human preferences is essential for safe and useful LLMs. Previous works mainly adopt reinforcement learning (RLHF) and direct preference optimization (DPO) with human feedback for alignment.…

Computation and Language · Computer Science 2023-10-03 Tianci Xue , Ziqi Wang , Heng Ji

Currently, pre-trained language models (PLMs) do not cope well with the distribution shift problem, resulting in models trained on the training set failing in real test scenarios. To address this problem, the test-time adaptation (TTA)…

Computation and Language · Computer Science 2023-04-26 Yi Su , Yixin Ji , Juntao Li , Hai Ye , Min Zhang

The development of state-of-the-art generative large language models (LLMs) disproportionately relies on English-centric tokenizers, vocabulary and pre-training data. Despite the fact that some LLMs have multilingual capabilities, recent…

Computation and Language · Computer Science 2024-09-27 Atsuki Yamaguchi , Aline Villavicencio , Nikolaos Aletras

Motivation: Prediction of the interaction affinity between proteins and compounds is a major challenge in the drug discovery process. WideDTA is a deep-learning based prediction model that employs chemical and biological textual sequence…

Quantitative Methods · Quantitative Biology 2019-02-13 Hakime Öztürk , Elif Ozkirimli , Arzucan Özgür

Large language models (LLMs) and small language models (SLMs) are being adopted at remarkable speed, although their safety still remains a serious concern. With the advent of multilingual S/LLMs, the question now becomes a matter of scale:…

Objective: Latent diffusion models (LDM) could alleviate data scarcity challenges affecting machine learning development for medical imaging. However, medical LDM strategies typically rely on short-prompt text encoders, nonmedical LDMs, or…

Image and Video Processing · Electrical Eng. & Systems 2026-01-09 Emerson P. Grabke , Babak Taati , Masoom A. Haider

As large language models (LLMs) are widely adopted, new safety issues and policies emerge, to which existing safety classifiers do not generalize well. If we have only observed a few examples of violations of a new safety rule, how can we…

Machine Learning · Computer Science 2023-10-27 Ananth Balashankar , Xiao Ma , Aradhana Sinha , Ahmad Beirami , Yao Qin , Jilin Chen , Alex Beutel

Recent works on large language models (LLMs) have demonstrated the impact of prompting strategies and fine-tuning techniques on their reasoning capabilities. Yet, their effectiveness on clinical natural language inference (NLI) remains…

Computation and Language · Computer Science 2025-07-08 Mael Jullien , Marco Valentino , Leonardo Ranaldi , Andre Freitas

Machine Learning-guided solutions for protein learning tasks have made significant headway in recent years. However, success in scientific discovery tasks is limited by the accessibility of well-defined and labeled in-domain data. To tackle…

Machine Learning · Computer Science 2023-01-06 Ria Vinod , Pin-Yu Chen , Payel Das

Pre-trained Language Models (PLMs) may be poisonous with backdoors or bias injected by the suspicious attacker during the fine-tuning process. A core challenge of purifying potentially poisonous PLMs is precisely finding poisonous…

Computation and Language · Computer Science 2023-05-09 Zhiyuan Zhang , Deli Chen , Hao Zhou , Fandong Meng , Jie Zhou , Xu Sun

Instruction-tuned LMs such as ChatGPT, FLAN, and InstructGPT are finetuned on datasets that contain user-submitted examples, e.g., FLAN aggregates numerous open-source datasets and OpenAI leverages examples submitted in the browser…

Computation and Language · Computer Science 2023-05-02 Alexander Wan , Eric Wallace , Sheng Shen , Dan Klein

Large Language Models (LLMs) have reshaped natural language processing with their impressive capabilities. However, their ever-increasing size has raised concerns about their effective deployment and the need for LLM compression. This study…

Vision Language Models (VLMs) have become essential backbones for multimodal intelligence, yet significant safety challenges limit their real-world application. While textual inputs are often effectively safeguarded, adversarial visual…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Yi Ding , Bolian Li , Ruqi Zhang

Vehicle crashes involve complex interactions between road users, split-second decisions, and challenging environmental conditions. Among these, two-vehicle crashes are the most prevalent, accounting for approximately 70% of roadway crashes…

Artificial Intelligence · Computer Science 2025-10-16 Boyou Chen , Gerui Xu , Zifei Wang , Huizhong Guo , Ananna Ahmed , Zhaonan Sun , Zhen Hu , Kaihan Zhang , Shan Bao

Large Language Models (LLMs) exhibit impressive capabilities but also present risks such as biased content generation and privacy issues. One of the current alignment techniques includes principle-driven integration, but it faces challenges…

Computation and Language · Computer Science 2025-05-30 Yi Luo , Zhenghao Lin , Yuhao Zhang , Jiashuo Sun , Chen Lin , Chengjin Xu , Xiangdong Su , Yelong Shen , Jian Guo , Yeyun Gong