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Automatic diagnosis of malignant prostate cancer patients from mpMRI has been studied heavily in the past years. Model interpretation and domain drift have been the main road blocks for clinical utilization. As an extension from our…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Weiwei Zong , Eric Carver , Simeng Zhu , Eric Schaff , Daniel Chapman , Joon Lee , Hassan Bagher Ebadian , Indrin Chetty , Benjamin Movsas , Winston Wen , Tarik Alafif , Xiangyun Zong

Magnetic Resonance Imaging is a critical imaging modality in clinical diagnosis and research, yet its complexity and heterogeneity hinder scalable, generalizable machine learning. Although foundation models have revolutionized language and…

We present a fully automated, anatomically guided deep learning pipeline for prostate cancer (PCa) risk stratification using routine MRI. The pipeline integrates three key components: an nnU-Net module for segmenting the prostate gland and…

Foundation models have demonstrated remarkable success across diverse domains and tasks, primarily due to the thrive of large-scale, diverse, and high-quality datasets. However, in the field of medical imaging, the curation and assembling…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Zhongying Deng , Cheng Tang , Ziyan Huang , Jiashi Lin , Ying Chen , Junzhi Ning , Chenglong Ma , Jiyao Liu , Wei Li , Yinghao Zhu , Shujian Gao , Yanyan Huang , Sibo Ju , Yanzhou Su , Pengcheng Chen , Wenhao Tang , Tianbin Li , Haoyu Wang , Yuanfeng Ji , Hui Sun , Shaobo Min , Liang Peng , Feilong Tang , Haochen Xue , Rulin Zhou , Chaoyang Zhang , Wenjie Li , Shaohao Rui , Weijie Ma , Xingyue Zhao , Yibin Wang , Kun Yuan , Zhaohui Lu , Shujun Wang , Jinjie Wei , Lihao Liu , Dingkang Yang , Lin Wang , Yulong Li , Haolin Yang , Yiqing Shen , Lequan Yu , Xiaowei Hu , Yun Gu , Yicheng Wu , Benyou Wang , Minghui Zhang , Angelica I. Aviles-Rivero , Qi Gao , Hongming Shan , Xiaoyu Ren , Fang Yan , Hongyu Zhou , Haodong Duan , Maosong Cao , Shanshan Wang , Bin Fu , Xiaomeng Li , Zhi Hou , Chunfeng Song , Lei Bai , Yuan Cheng , Yuandong Pu , Xiang Li , Wenhai Wang , Hao Chen , Jiaxin Zhuang , Songyang Zhang , Huiguang He , Mengzhang Li , Bohan Zhuang , Zhian Bai , Rongshan Yu , Liansheng Wang , Yukun Zhou , Xiaosong Wang , Xin Guo , Guanbin Li , Xiangru Lin , Dakai Jin , Mianxin Liu , Wenlong Zhang , Qi Qin , Conghui He , Yuqiang Li , Ye Luo , Nanqing Dong , Jie Xu , Wenqi Shao , Bo Zhang , Qiujuan Yan , Yihao Liu , Jun Ma , Zhi Lu , Yuewen Cao , Zongwei Zhou , Jianming Liang , Shixiang Tang , Qi Duan , Dongzhan Zhou , Chen Jiang , Yuyin Zhou , Yanwu Xu , Jiancheng Yang , Shaoting Zhang , Xiaohong Liu , Siqi Luo , Yi Xin , Chaoyu Liu , Haochen Wen , Xin Chen , Alejandro Lozano , Min Woo Sun , Yuhui Zhang , Yue Yao , Xiaoxiao Sun , Serena Yeung-Levy , Xia Li , Jing Ke , Chunhui Zhang , Zongyuan Ge , Ming Hu , Jin Ye , Zhifeng Li , Yirong Chen , Yu Qiao , Junjun He

In post-operative radiotherapy for prostate cancer, the cancerous prostate gland has been surgically removed, so the clinical target volume (CTV) to be irradiated encompasses the microscopic spread of tumor cells, which cannot be visualized…

Prostate cancer being one of the frequently diagnosed malignancy in men, the rising demand for biopsies places a severe workload on pathologists. The grading procedure is tedious and subjective, motivating the development of automated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Riddhasree Bhattacharyya , Pallabi Dutta , Sushmita Mitra

Pathological assessment guides lung cancer diagnosis, treatment selection, and prognostic evaluation, yet current CPath approaches rely on task-specific models for isolated objectives. Although pan-cancer foundation models offer…

Prostate cancer is one of the most common causes of cancer deaths in men. There is a growing demand for noninvasively and accurately diagnostic methods that facilitate the current standard prostate cancer risk assessment in clinical…

Image and Video Processing · Electrical Eng. & Systems 2021-12-30 Ping-Chang Lin , Teodora Szasz , Hakizumwami B. Runesha

Radiological analysis increasingly benefits from pretrained visual representations that can support heterogeneous downstream tasks across imaging modalities. In this work, we introduce OmniRad, a self-supervised radiological foundation…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Luca Zedda , Andrea Loddo , Cecilia Di Ruberto

Prostate cancer is one of the leading causes of cancer-related death in men worldwide. Like many cancers, diagnosis involves expert integration of heterogeneous patient information such as imaging, clinical risk factors, and more. For this…

Image and Video Processing · Electrical Eng. & Systems 2023-10-02 Gregory Holste , Douwe van der Wal , Hans Pinckaers , Rikiya Yamashita , Akinori Mitani , Andre Esteva

Prostate biopsy and image-guided treatment procedures are often performed under the guidance of ultrasound fused with magnetic resonance images (MRI). Accurate image fusion relies on accurate segmentation of the prostate on ultrasound…

Image and Video Processing · Electrical Eng. & Systems 2022-09-07 Sulaiman Vesal , Iani Gayo , Indrani Bhattacharya , Shyam Natarajan , Leonard S. Marks , Dean C Barratt , Richard E. Fan , Yipeng Hu , Geoffrey A. Sonn , Mirabela Rusu

Vision foundation models (VFMs) are pre-trained on extensive image datasets to learn general representations for diverse types of data. These models can subsequently be fine-tuned for specific downstream tasks, significantly boosting…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Shansong Wang , Mojtaba Safari , Qiang Li , Chih-Wei Chang , Richard LJ Qiu , Justin Roper , David S. Yu , Xiaofeng Yang

Multi-sequence Magnetic Resonance Imaging (MRI) offers remarkable versatility, enabling the distinct visualization of different tissue types. Nevertheless, the inherent heterogeneity among MRI sequences poses significant challenges to the…

Automated diagnosis with artificial intelligence has emerged as a promising area in the realm of medical imaging, while the interpretability of the introduced deep neural networks still remains an urgent concern. Although contemporary…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Binghua Li , Jie Mao , Zhe Sun , Chao Li , Qibin Zhao , Toshihisa Tanaka

Diagnosing rare diseases presents a common challenge in clinical practice, necessitating the expertise of specialists for accurate identification. The advent of machine learning offers a promising solution, while the development of such…

Machine Learning · Computer Science 2024-03-12 Yifan Wu , Yang Liu , Yue Yang , Michael S. Yao , Wenli Yang , Xuehui Shi , Lihong Yang , Dongjun Li , Yueming Liu , James C. Gee , Xuan Yang , Wenbin Wei , Shi Gu

The interpretation of prostate MRI suffers from low agreement across radiologists due to the subtle differences between cancer and normal tissue. Image registration addresses this issue by accurately mapping the ground-truth cancer labels…

Multimodal language models (MLMs) show promise for clinical decision support and diagnostic reasoning, raising the prospect of end-to-end automated medical image interpretation. However, clinicians are highly selective in adopting AI tools;…

Artificial Intelligence · Computer Science 2025-08-06 Mahtab Bigverdi , Wisdom Ikezogwo , Kevin Zhang , Hyewon Jeong , Mingyu Lu , Sungjae Cho , Linda Shapiro , Ranjay Krishna

Cardiac magnetic resonance imaging (CMR), considered the gold standard for noninvasive cardiac assessment, is a diverse and complex modality requiring a wide variety of image processing tasks for comprehensive assessment of cardiac…

Image and Video Processing · Electrical Eng. & Systems 2025-12-03 Athira J Jacob , Indraneel Borgohain , Teodora Chitiboi , Puneet Sharma , Dorin Comaniciu , Daniel Rueckert

Purpose: Accurate segmentation of prostate cancer on magnetic resonance (MR) images is crucial for planning image-guided interventions such as targeted biopsies, cryoablation, and radiotherapy. However, subtle and variable tumour…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Junqing Yang , Natasha Thorley , Ahmed Nadeem Abbasi , Shonit Punwani , Zion Tse , Yipeng Hu , Shaheer U. Saeed

Thyroid nodule classification using ultrasound imaging is essential for early diagnosis and clinical decision-making; however, despite promising performance on in-distribution data, existing deep learning methods often exhibit limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Yangmei Chen , Zhongyuan Zhang , Xikun Zhang , Xinyu Hao , Mingliang Hou , Renqiang Luo , Ziqi Xu