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Complex single-objective bounded problems are often difficult to solve. In evolutionary computation methods, since the proposal of differential evolution algorithm in 1997, it has been widely studied and developed due to its simplicity and…

Neural and Evolutionary Computing · Computer Science 2024-04-26 Sichen Tao , Ruihan Zhao , Kaiyu Wang , Shangce Gao

Explainability of neural network prediction is essential to understand feature importance and gain interpretable insight into neural network performance. However, explanations of neural network outcomes are mostly limited to visualization,…

Machine Learning · Computer Science 2023-07-13 Arnab Neelim Mazumder , Niall Lyons , Ashutosh Pandey , Avik Santra , Tinoosh Mohsenin

Inference-time compute has re-emerged as a practical way to improve LLM reasoning. Most test-time scaling (TTS) algorithms rely on autoregressive decoding, which is ill-suited to discrete diffusion language models (dLLMs) due to their…

Machine Learning · Computer Science 2026-05-06 Jinbin Bai , Yixuan Li , Yuchen Zhu , Yi Xin , Qingyu Shi , Aosong Feng , Xiaohong Liu , Molei Tao , Jianru Xue , Xiangtai Li , Ming-Hsuan Yang

Proteins govern most biological functions essential for life, but achieving controllable protein discovery and optimization remains challenging. Recently, machine learning-assisted protein editing (MLPE) has shown promise in accelerating…

Artificial Intelligence · Computer Science 2024-11-19 Mingze Yin , Hanjing Zhou , Yiheng Zhu , Miao Lin , Yixuan Wu , Jialu Wu , Hongxia Xu , Chang-Yu Hsieh , Tingjun Hou , Jintai Chen , Jian Wu

Large Language Models (LLMs) have achieved significant success across various NLP tasks. However, their massive computational costs limit their widespread use, particularly in real-time applications. Structured pruning offers an effective…

Machine Learning · Computer Science 2025-03-06 Shengkun Tang , Oliver Sieberling , Eldar Kurtic , Zhiqiang Shen , Dan Alistarh

Knowledge editing aims to update outdated information in Large Language Models (LLMs). A representative line of study is locate-then-edit methods, which typically employ causal tracing to identify the modules responsible for recalling…

Computation and Language · Computer Science 2025-03-18 Haowen Pan , Xiaozhi Wang , Yixin Cao , Zenglin Shi , Xun Yang , Juanzi Li , Meng Wang

Large language models (LLMs) have demonstrated impressive capabilities in code generation, where the natural language prompt plays a crucial role in conveying user intent to the model. However, prior studies have shown that LLMs are highly…

Software Engineering · Computer Science 2025-12-11 Shuhan Liu , Xing Hu , Kerui Huang , Xiaohu Yang , David Lo , Xin Xia

Training reliable tool-augmented agents remains a significant challenge, largely due to the difficulty of credit assignment in multi-step reasoning. While process-level reward models offer a promising direction, existing LLM-based judges…

Artificial Intelligence · Computer Science 2026-04-28 Yuxuan Jiang , Francis Ferraro

Strings are a natural representation of biological data such as DNA, RNA and protein sequences. The problem of finding a string that summarizes a set of sequences has direct application in relative compression algorithms for genome and…

Data Structures and Algorithms · Computer Science 2019-12-06 P. Mirabal , J. Abreu , D. Seco

Generative sequence modeling faces a fundamental tension between the expressivity of Transformers and the efficiency of linear sequence models. Existing efficient architectures are theoretically bounded by shallow, single-step linear…

Machine Learning · Computer Science 2026-02-13 Jie Jiang , Ke Cheng , Xin Xu , Mengyang Pang , Tianhao Lu , Jiaheng Li , Yue Liu , Yuan Wang , Jun Zhang , Huan Yu , Zhouchen Lin

Protein fitness optimization involves finding a protein sequence that maximizes desired quantitative properties in a combinatorially large design space of possible sequences. Recent advances in steering protein generative models (e.g.,…

Biomolecules · Quantitative Biology 2025-10-22 Jason Yang , Wenda Chu , Daniel Khalil , Raul Astudillo , Bruce J. Wittmann , Frances H. Arnold , Yisong Yue

Large Language Models (LLMs) often rely on long chain-of-thought (CoT) reasoning to solve complex tasks. While effective, these trajectories are frequently inefficient, leading to high latency from excessive token generation, or unstable…

We propose a constraint learning schema for fine-tuning Large Language Models (LLMs) with attribute control. Given a training corpus and control criteria formulated as a sequence-level constraint on model outputs, our method fine-tunes the…

Computation and Language · Computer Science 2024-10-10 Tao Meng , Ninareh Mehrabi , Palash Goyal , Anil Ramakrishna , Aram Galstyan , Richard Zemel , Kai-Wei Chang , Rahul Gupta , Charith Peris

Language models (LMs) have yielded impressive results on many language reasoning tasks, but their unexpected errors raise doubts about their reasoning abilities. In light of this, there is growing interest in finetuning/prompting LMs with…

Computation and Language · Computer Science 2023-05-23 Aaron Chan , Zhiyuan Zeng , Wyatt Lake , Brihi Joshi , Hanjie Chen , Xiang Ren

Long chain-of-thought (Long CoT) reasoning improves performance on multi-step problems, but it also induces overthinking: models often generate low-yield reasoning that increases inference cost and latency. This inefficiency is especially…

Computation and Language · Computer Science 2026-05-14 Chenjun Xu , Zhennan Zhou , Zhan Su , Bill Howe , Lucy Lu Wang , Bingbing Wen

How to edit the knowledge in multi-step reasoning has become the major challenge in the knowledge editing (KE) of large language models (LLMs). The difficulty arises because the hallucinations of LLMs during multi-step reasoning often lead…

Computation and Language · Computer Science 2024-11-12 Yiwei Wang , Muhao Chen , Nanyun Peng , Kai-Wei Chang

Recent advances in Large Language Models (LLMs) show that extending the length of reasoning chains significantly improves performance on complex tasks. While revealing these reasoning traces helps users better follow, verify, and learn from…

Computation and Language · Computer Science 2025-10-14 Jiayu Ding , Lei Cui , Li Dong , Nanning Zheng , Furu Wei

String edit distances have been used for decades in applications ranging from spelling correction and web search suggestions to DNA analysis. Most string edit distances are variations of the Levenshtein distance and consider only…

Genomics · Quantitative Biology 2022-05-12 Taylor Petty , Jan Hannig , Tunde I Huszar , Hari Iyer

Structured pruning methods designed for Large Language Models (LLMs) generally focus on identifying and removing the least important components to optimize model size. However, in this work, we question this prevalent approach by instead…

Machine Learning · Computer Science 2026-02-26 Neha Verma , Kenton Murray , Kevin Duh

We consider small-data, large-scale decision problems in which a firm must make many operational decisions simultaneously (e.g., across a large product portfolio) while observing only a few, potentially noisy, data points per instance.…

Machine Learning · Computer Science 2026-02-04 Zishi Zhang , Jinhui Han , Ming Hu , Yijie Peng