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Large Language Models (LLMs) are increasingly used in clinical settings, where sensitivity to linguistic uncertainty can influence diagnostic interpretation and decision-making. Yet little is known about where such epistemic cues are…

Computation and Language · Computer Science 2025-12-01 Srivarshinee Sridhar , Raghav Kaushik Ravi , Kripabandhu Ghosh

Uncertainty quantification is essential for assessing the reliability and trustworthiness of modern AI systems. Among existing approaches, verbalized uncertainty, where models express their confidence through natural language, has emerged…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Weihao Xuan , Qingcheng Zeng , Heli Qi , Junjue Wang , Naoto Yokoya

Large language models (LLMs) are rapidly being integrated into computational social science research, yet their blackboxed training and designed stochastic elements in inference pose unique challenges for scientific inquiry. This article…

Computers and Society · Computer Science 2025-12-08 Bolun Zhang , Linzhuo Li , Yunqi Chen , Qinlin Zhao , Zihan Zhu , Xiaoyuan Yi , Xing Xie

Large Language Models (LLMs) have the tendency to hallucinate, i.e., to sporadically generate false or fabricated information. This presents a major challenge, as hallucinations often appear highly convincing and users generally lack the…

Vision-language models (VLMs) often produce chain-of-thought (CoT) explanations that sound plausible yet fail to reflect the underlying decision process, undermining trust in high-stakes clinical use. Existing evaluations rarely catch this…

Brain tumor diagnosis is largely dependent on Magnetic Resonance Imaging (MRI) evaluation, which requires radiologists to synthesize thousands of images across multiple 3D sequences and longitudinal studies. This process requires advanced…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Shiv Ghosh , Junayd Lateef , Chih-Hua Liu , Yannan Yu , Andreas M. Rauschecker , Madhumita Sushil

The ability to distinguish subtle differences between visually similar images is essential for diverse domains such as industrial anomaly detection, medical imaging, and aerial surveillance. While comparative reasoning benchmarks for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Minkyu Kim , Sangheon Lee , Dongmin Park

Recent advances in Vision-Language Models (VLMs) have demonstrated impressive multimodal understanding in general domains. However, their applicability to decision-oriented domains such as hospitality remains largely unexplored. In this…

Artificial Intelligence · Computer Science 2026-03-10 Jeongwoo Lee , Baek Duhyeong , Eungyeol Han , Soyeon Shin , Gukin han , Seungduk Kim , Jaehyun Jeon , Taewoo Jeong

Large language models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence technology which is rapidly evolving and promises to aid in medical diagnosis. However, the correctness and the accuracy of their returns has…

Computation and Language · Computer Science 2024-02-07 Dimitrios P. Panagoulias , Maria Virvou , George A. Tsihrintzis

Vision-Language Models (VLMs) are increasingly used as perceptual modules for visual content reasoning, including through captioning and DeepFake detection. In this work, we expose a critical vulnerability of VLMs when exposed to subtle,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Jordan Vice , Naveed Akhtar , Yansong Gao , Richard Hartley , Ajmal Mian

Vision-language models (VLMs) can couple visual perception with open-ended clinical reasoning, making them attractive for computational histopathology. However, fine-tuning billions of parameters on scarce, expert-annotated pathology data…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Franciskus Xaverius Erick , Johanna Paula Müller , Bernhard Kainz

Medical large vision-language models (LVLMs) have demonstrated promising performance across various single-image question answering (QA) benchmarks, yet their capability in processing multi-image clinical scenarios remains underexplored.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Xikai Yang , Juzheng Miao , Yuchen Yuan , Jiaze Wang , Qi Dou , Jinpeng Li , Pheng-Ann Heng

Multi-modal large language models (MLLMs) have demonstrated remarkable vision-language capabilities, primarily due to the exceptional in-context understanding and multi-task learning strengths of large language models (LLMs). The advent of…

Computer Vision and Pattern Recognition · Computer Science 2024-02-01 Jianing Li , Xi Nan , Ming Lu , Li Du , Shanghang Zhang

With the rapid advancement of deep learning, particularly in the field of medical image analysis, an increasing number of Vision-Language Models (VLMs) are being widely applied to solve complex health and biomedical challenges. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Haiyang Yu , Siyang Yi , Ke Niu , Minghan Zhuo , Bin Li

Uncertainty Quantification (UQ) research has primarily focused on closed-book factual question answering (QA), while contextual QA remains unexplored, despite its importance in real-world applications. In this work, we focus on UQ for the…

Large Language Models (LLMs) are increasingly deployed to autonomously solve real-world tasks. A key ingredient for this is the LLM Function-Calling paradigm, a widely used approach for equipping LLMs with tool-use capabilities. However, an…

Computation and Language · Computer Science 2026-04-28 Zihuiwen Ye , Lukas Aichberger , Michael Kirchhof , Sinead Williamson , Luca Zappella , Yarin Gal , Arno Blaas , Adam Golinski

Mathematical models are essential tools to study how the cardiovascular system maintains homeostasis. The utility of such models is limited by the accuracy of their predictions, which can be determined by uncertainty quantification (UQ). A…

Quantitative Methods · Quantitative Biology 2018-07-20 Andrew D. Marquis , Andrea Arnold , Caron Dean , Brian E. Carlson , Mette S. Olufsen

Vision-Language Models (VLMs) have emerged as powerful tools for image understanding tasks, yet their practical deployment remains hindered by significant architectural heterogeneity across model families. This paper introduces UVLM…

Machine Learning · Computer Science 2026-03-17 Joan Perez , Giovanni Fusco

Despite recent progress in systematic evaluation frameworks, benchmarking the uncertainty of large language models (LLMs) remains a highly challenging task. Existing methods for benchmarking the uncertainty of LLMs face three key…

Computation and Language · Computer Science 2025-06-05 Xunzhi Wang , Zhuowei Zhang , Gaonan Chen , Qiongyu Li , Bitong Luo , Zhixin Han , Haotian Wang , Zhiyu li , Hang Gao , Mengting Hu

When does a large language model (LLM) know what it does not know? Uncertainty quantification (UQ) provides measures of uncertainty, such as an estimate of the confidence in an LLM's generated output, and is therefore increasingly…

Computation and Language · Computer Science 2025-10-17 Debarun Bhattacharjya , Balaji Ganesan , Junkyu Lee , Radu Marinescu , Katsiaryna Mirylenka , Michael Glass , Xiao Shou