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Inferring the causal relationships among a set of variables in the form of a directed acyclic graph (DAG) is an important but notoriously challenging problem. Recently, advancements in high-throughput genomic perturbation screens have…

Machine Learning · Computer Science 2025-10-03 Seong Woo Han , Daniel Duy Vo , Brielin C. Brown

Many real-world decision-making tasks require learning causal relationships between a set of variables. Traditional causal discovery methods, however, require that all variables are observed, which is often not feasible in practical…

Methodology · Statistics 2023-06-27 Raj Agrawal , Chandler Squires , Neha Prasad , Caroline Uhler

Causal discovery from observational data is a challenging task that can only be solved up to a set of equivalent solutions, called an equivalence class. Such classes, which are often large in size, encode uncertainties about the orientation…

Machine Learning · Computer Science 2022-03-01 Philippe Brouillard , Perouz Taslakian , Alexandre Lacoste , Sebastien Lachapelle , Alexandre Drouin

This PhD thesis contains several contributions to the field of statistical causal modeling. Statistical causal models are statistical models embedded with causal assumptions that allow for the inference and reasoning about the behavior of…

Machine Learning · Statistics 2021-10-05 Martin Emil Jakobsen

Learning causal structures from interventional data is a fundamental problem with broad applications across various fields. While many previous works have focused on recovering the entire causal graph, in practice, there are scenarios where…

Machine Learning · Computer Science 2023-11-01 Kirankumar Shiragur , Jiaqi Zhang , Caroline Uhler

The aim in many sciences is to understand the mechanisms that underlie the observed distribution of variables, starting from a set of initial hypotheses. Causal discovery allows us to infer mechanisms as sets of cause and effect…

Machine Learning · Computer Science 2025-03-05 Ashka Shah , Adela DePavia , Nathaniel Hudson , Ian Foster , Rick Stevens

Causal inference is a critical task across fields such as healthcare, economics, and the social sciences. While recent advances in machine learning, especially those based on the deep-learning architectures, have shown potential in…

Machine Learning · Statistics 2024-12-30 Manqing Liu , David R. Bellamy , Andrew L. Beam

Learning DAG structures from purely observational data remains a long-standing challenge across scientific domains. An emerging line of research leverages the score of the data distribution to initially identify a topological order of the…

Machine Learning · Computer Science 2026-01-27 Vy Vo , He Zhao , Trung Le , Edwin V. Bonilla , Dinh Phung

The invariance properties of interventional distributions relative to the observational distribution, and how these properties allow us to refine Markov equivalence classes (MECs) of DAGs, is central to causal DAG discovery algorithms that…

Statistics Theory · Mathematics 2020-06-09 Liam Solus

Causal discovery, the task of inferring causal structure from data, has the potential to uncover mechanistic insights from biological experiments, especially those involving perturbations. However, causal discovery algorithms over larger…

Machine Learning · Computer Science 2025-04-01 Menghua Wu , Yujia Bao , Regina Barzilay , Tommi Jaakkola

For two causal structures with the same set of visible variables, one is said to observationally dominate the other if the set of distributions over the visible variables realizable by the first contains the set of distributions over the…

Machine Learning · Statistics 2025-02-24 Marina Maciel Ansanelli , Elie Wolfe , Robert W. Spekkens

This article presents a novel method for causal discovery with generalized structural equation models suited for analyzing diverse types of outcomes, including discrete, continuous, and mixed data. Causal discovery often faces challenges…

Methodology · Statistics 2023-10-26 Minjie Wang , Xiaotong Shen , Wei Pan

We assume that we have observational data generated from an unknown underlying directed acyclic graph (DAG) model. A DAG is typically not identifiable from observational data, but it is possible to consistently estimate the equivalence…

Methodology · Statistics 2009-09-02 Marloes H. Maathuis , Markus Kalisch , Peter Bühlmann

We focus on causal discovery in the presence of measurement error in linear systems where the mixing matrix, i.e., the matrix indicating the independent exogenous noise terms pertaining to the observed variables, is identified up to…

Machine Learning · Computer Science 2022-11-09 Yuqin Yang , AmirEmad Ghassami , Mohamed Nafea , Negar Kiyavash , Kun Zhang , Ilya Shpitser

With observational data alone, causal structure learning is a challenging problem. The task becomes easier when having access to data collected from perturbations of the underlying system, even when the nature of these is unknown. Existing…

Methodology · Statistics 2023-10-10 Armeen Taeb , Juan L. Gamella , Christina Heinze-Deml , Peter Bühlmann

Evaluating graphs learned by causal discovery algorithms is difficult: The number of edges that differ between two graphs does not reflect how the graphs differ with respect to the identifying formulas they suggest for causal effects. We…

Machine Learning · Statistics 2024-07-12 Leonard Henckel , Theo Würtzen , Sebastian Weichwald

Differentiable causal discovery has made significant advancements in the learning of directed acyclic graphs. However, its application to real-world datasets remains restricted due to the ubiquity of latent confounders and the requirement…

Machine Learning · Computer Science 2024-06-18 Pingchuan Ma , Rui Ding , Qiang Fu , Jiaru Zhang , Shuai Wang , Shi Han , Dongmei Zhang

Simulated DAG models may exhibit properties that, perhaps inadvertently, render their structure identifiable and unexpectedly affect structure learning algorithms. Here, we show that marginal variance tends to increase along the causal…

Machine Learning · Statistics 2021-11-11 Alexander G. Reisach , Christof Seiler , Sebastian Weichwald

We conjecture that the worst case number of experiments necessary and sufficient to discover a causal graph uniquely given its observational Markov equivalence class can be specified as a function of the largest clique in the Markov…

Artificial Intelligence · Computer Science 2012-06-18 Frederick Eberhardt

Causal discovery is a data-driven paradigm for analyzing complex systems, while physics-based models, such as ordinary differential equations (ODEs), provide mechanistic structure for real-world dynamical processes. Integrating these…

Machine Learning · Computer Science 2026-05-21 Jianhong Chen , Naichen Shi , Xubo Yue
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