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The ubiquity of topographic maps in the brain has long been known, and molecular mechanisms for the formation of topographic organization of neural systems have been revealed. Less attention has been given to the question of why are the…

Neurons and Cognition · Quantitative Biology 2018-11-13 Shigeko Takahashi

The human brain's computational prowess emerges not despite but because of its inherent "non-ideal factors"-noise, heterogeneity, structural irregularities, decentralized plasticity, systemic errors, and chaotic dynamics-challenging…

Neurons and Cognition · Quantitative Biology 2026-01-13 Da-Zheng Feng , Hao-Xuan Du

In order to reproduce human behaviour in dynamic traffic situations, a computational representation of the requisite mental processes used to carry out the complex driving tasks is required. A single cognitive factor has been developed and…

Neurons and Cognition · Quantitative Biology 2021-08-17 Firas Lethaus , Robert Kaul

The human visual system exhibits non-uniform spatial resolution across the visual field, which is characterized by the cortical magnification factor (CMF) that reflects its anatomical basis. However, current approaches for quantifying CMF…

Neurons and Cognition · Quantitative Biology 2025-12-09 Yujian Xiong , Negar Jalili Mallak , Yanshuai Tu , Zhong-Lin Lu , Yalin Wang

Adaptive reasoning enables humans to flexibly adjust inference strategies when environmental rules or contexts change, yet its underlying neural dynamics remain unclear. This study investigated the neurophysiological mechanisms of adaptive…

Artificial Intelligence · Computer Science 2025-11-12 Jun-Young Kim , Young-Seok Kweon , Gi-Hwan Shin , Seong-Whan Lee

Feature Transformation (FT) crafts new features from original ones via mathematical operations to enhance dataset expressiveness for downstream models. However, existing FT methods exhibit critical limitations: discrete search struggles…

Machine Learning · Computer Science 2025-05-22 Nanxu Gong , Zijun Li , Sixun Dong , Haoyue Bai , Wangyang Ying , Xinyuan Wang , Yanjie Fu

Brain-inspired computing architectures attempt to mimic the computations performed in the neurons and the synapses in the human brain in order to achieve its efficiency in learning and cognitive tasks. In this work, we demonstrate the…

Emerging Technologies · Computer Science 2017-12-20 Abhronil Sengupta , Priyadarshini Panda , Parami Wijesinghe , Yusung Kim , Kaushik Roy

The complex world around us is inherently multimodal and sequential (continuous). Information is scattered across different modalities and requires multiple continuous sensors to be captured. As machine learning leaps towards better…

Machine Learning · Computer Science 2019-11-25 Amir Zadeh , Chengfeng Mao , Kelly Shi , Yiwei Zhang , Paul Pu Liang , Soujanya Poria , Louis-Philippe Morency

Neural collaborative filtering (NCF) and recurrent recommender systems (RRN) have been successful in modeling user-item relational data. However, they are also limited in their assumption of static or sequential modeling of relational data…

Machine Learning · Computer Science 2018-02-14 Xian Wu , Baoxu Shi , Yuxiao Dong , Chao Huang , Nitesh Chawla

Hardware-based neuromorphic computing remains an elusive goal with the potential to profoundly impact future technologies and deepen our understanding of emergent intelligence. The learning-from-mistakes algorithm is one of the few training…

Disordered Systems and Neural Networks · Physics 2025-06-23 Frank Barrows , Jonathan Lin , Francesco Caravelli , Dante R. Chialvo

Probabilistic inference offers a principled framework for understanding both behaviour and cortical computation. However, two basic and ubiquitous properties of cortical responses seem difficult to reconcile with probabilistic inference:…

Neurons and Cognition · Quantitative Biology 2017-01-03 Laurence Aitchison , Máté Lengyel

Topology optimization (TO) is a family of computational methods that derive near-optimal geometries from formal problem descriptions. Despite their success, established TO methods are limited to generating single solutions, restricting the…

Machine Learning · Computer Science 2025-06-18 Andreas Radler , Eric Volkmann , Johannes Brandstetter , Arturs Berzins

Computational drug repositioning aims to discover new therapeutic diseases for marketed drugs and has the advantages of low cost, short development cycle, and high controllability compared to traditional drug development. The matrix…

Machine Learning · Computer Science 2021-11-30 Xinxing Yang , Genke Yangand Jian Chu

Computational models of cortical activity provide insight into the mechanisms of higher-order processing in the human brain including planning, perception and the control of movement. Activity in the cortex is ongoing even in the absence of…

Neurons and Cognition · Quantitative Biology 2023-07-07 Lysea Haggie , Thor Besier , Angus McMorland

The fundamental topology of manufacturing has not undergone a paradigm-level transformation since Henry Ford's moving assembly line in 1913. Every major innovation of the past century, from the Toyota Production System to Industry 4.0, has…

Artificial Intelligence · Computer Science 2026-03-06 Xinmin Fang , Lingfeng Tao , Zhengxiong Li

Neuronal circuits formed in the brain are complex with intricate connection patterns. Such complexity is also observed in the retina as a relatively simple neuronal circuit. A retinal ganglion cell receives excitatory inputs from neurons in…

Neurons and Cognition · Quantitative Biology 2020-03-03 Shanshan Jia , Zhaofei Yu , Arno Onken , Yonghong Tian , Tiejun Huang , Jian K. Liu

One frequently wishes to learn a range of similar tasks as efficiently as possible, re-using knowledge across tasks. In artificial neural networks, this is typically accomplished by conditioning a network upon task context by injecting…

Machine Learning · Computer Science 2025-11-26 Ari S. Benjamin , Kyle Daruwalla , Christian Pehle , Abdul-Malik Zekri , Anthony M. Zador

For long it has been known that specific patterns of folding are necessary for an optimally functioning brain. For instance, lissencephaly and polymicrogyria can lead to severe mental retardation, short life expectancy, epileptic seizures,…

Biological Physics · Physics 2020-04-03 Lucas da Costa Campos , Raphael Hornung , Gerhard Gompper , Jens Elgeti , Svenja Caspers

The efficacy of segmentation algorithms is frequently compromised by topological errors like overlapping regions, disrupted connections, and voids. To tackle this problem, we introduce a novel loss function, namely Topology-Aware Focal Loss…

Image and Video Processing · Electrical Eng. & Systems 2023-04-28 Andac Demir , Elie Massaad , Bulent Kiziltan

World modelling is essential for understanding and predicting the dynamics of complex systems by learning both spatial and temporal dependencies. However, current frameworks, such as Transformers and selective state-space models like…

Artificial Intelligence · Computer Science 2025-03-03 Li Nanbo , Firas Laakom , Yucheng Xu , Wenyi Wang , Jürgen Schmidhuber
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