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Machine learning interatomic potentials (MLIPs) are revolutionizing the field of molecular dynamics (MD) simulations. Recent MLIPs have tended towards more complex architectures trained on larger datasets. The resulting increase in…

The vastness of chemical space makes generalization a central challenge in the development of machine learning interatomic potentials (MLIPs). While MLIPs could enable large-scale atomistic simulations with near-quantum accuracy, their…

Chemical Physics · Physics 2026-03-20 Michal Sanocki , Julija Zavadlav

Integrating machine learning into reactive chemistry, materials discovery, and drug design is revolutionizing the development of novel molecules and materials. Machine Learning Interatomic Potentials (MLIPs) accurately predict energies and…

Chemical Physics · Physics 2025-07-04 Austin Rodriguez , Justin S. Smith , Jose L. Mendoza-Cortes

Machine learning interatomic potentials (MLIPs) provide a computationally efficient alternative to quantum mechanical simulations for predicting material properties. Message-passing graph neural networks, commonly used in these MLIPs, rely…

Chemical Physics · Physics 2025-09-08 Moin Uddin Maruf , Sungmin Kim , Zeeshan Ahmad

Machine learning interatomic potentials (MLIPs) are often trained with on-the-fly active learning, where sampled configurations from atomistic simulations are added to the training set. However, this approach is limited by the high…

Machine learning interatomic potentials (MLIPs) trained on large, chemically diverse datasets are revolutionizing computational chemistry, enabling molecular dynamics simulations of battery electrolytes with near-DFT accuracy over 10,000…

Machine Learning Interatomic Potentials (MLIPs) are becoming a central tool in simulation-based chemistry. However, like most deep learning models, MLIPs struggle to make accurate predictions on out-of-distribution data or when trained in a…

Machine Learning · Computer Science 2026-01-19 Dario Coscia , Pim de Haan , Max Welling

Interatomic potentials are key to uncovering microscopic structure-property relationships, essential for multiscale simulations and high-throughput experiments. For metallic glasses, their disordered atomic structure makes the development…

Machine learning interatomic potentials (MLIPs) have substantially advanced atomistic simulations in materials science and chemistry by balancing accuracy and computational efficiency. While leading MLIPs rely on representing atomic…

Materials Science · Physics 2025-05-05 Mingjian Wen , Wei-Fan Huang , Jin Dai , Santosh Adhikari

Lithium-based disordered rocksalts (LDRs), which are an important class of cathodes for advanced Li-ion batteries, represent a complex chemical and configurational space for conventional density functional theory (DFT)-based high-throughput…

Materials Science · Physics 2024-06-21 Vijay Choyal , Nidhish Sagar , Gopalakrishnan Sai Gautam

In the past two decades, machine learning potentials (MLP) have reached a level of maturity that now enables applications to large-scale atomistic simulations of a wide range of systems in chemistry, physics and materials science. Different…

Chemical Physics · Physics 2021-07-09 Emir Kocer , Tsz Wai Ko , Jörg Behler

Once trained, machine-learned interatomic potentials (MLIPs) provide a fast and accurate way to study catalytic reaction pathways, but their performance strongly depends on the training set. Here, we compare nine MLIPs trained with…

Local curvature of potential energy surfaces is critical for predicting certain experimental observables of molecules and materials from first principles, yet it remains far beyond reach for complex systems. In this work, we introduce a…

Machine Learning · Computer Science 2026-03-27 Bangchen Yin , Jian Ouyang , Zhen Fan , Kailai Lin , Hanshi Hu , Dingshun Lv , Weiluo Ren , Hai Xiao , Ji Chen , Changsu Cao

Machine learning interatomic potentials (MLIPs) enables molecular dynamics (MD) simulations with ab initio accuracy and has been applied to various fields of physical science. However, the performance and transferability of MLIPs are…

Chemical Physics · Physics 2024-04-16 Taoyong Cui , Chenyu Tang , Mao Su , Shufei Zhang , Yuqiang Li , Lei Bai , Yuhan Dong , Xingao Gong , Wanli Ouyang

A linear regression-based machine learned interatomic potential (MLIP) was developed for the silicon-carbon system. The MLIP was predominantly trained on structures discovered through a genetic algorithm, encompassing the entire…

Mesoscale and Nanoscale Physics · Physics 2024-03-26 Michael MacIsaac , Salil Bavdekar , Douglas Spearot , Ghatu Subhash

Universal machine learning interatomic potentials (uMLIPs) have emerged as powerful tools for accelerating atomistic simulations, offering scalable and efficient modeling with accuracy close to quantum calculations. However, their…

Materials Science · Physics 2025-07-17 Hendrik Kraß , Ju Huang , Seyed Mohamad Moosavi

We introduce a lightweight universal machine-learning interatomic potential (uMLIP), SevenNet-Nano, based on the graph neural network architecture SevenNet and enabled by a knowledge-distillation framework. The model inherits the broad…

Materials Science · Physics 2026-04-14 Sangmin Oh , Jinmu You , Jaesun Kim , Jiho Lee , Hyungmin An , Seungwu Han , Youngho Kang

Rapid development of universal machine learning potentials (uMLPs) and expansion of training data sets are reshaping the state of the art in atomistic simulation, highlighting the need for concurrent systematic benchmarking of their…

Materials Science · Physics 2026-03-02 Edan T. Marcial , Laxman Chaudhary , Olesya Gorbunova , Aleksey N. Kolmogorov

Interatomic potentials (IAPs), which describe the potential energy surface of atoms, are a fundamental input for atomistic simulations. However, existing IAPs are either fitted to narrow chemistries or too inaccurate for general…

Materials Science · Physics 2022-12-06 Chi Chen , Shyue Ping Ong

Universal machine learning interatomic potentials (uMLIPs) have recently been formulated and shown to generalize well. When applied out-of-sample, further data collection for improvement of the uMLIPs may, however, be required. In this work…

Materials Science · Physics 2025-12-11 Joe Pitfield , Mads-Peter Verner Christiansen , Bjørk Hammer
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