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We use topological data analysis to study "functional networks" that we construct from time-series data from both experimental and synthetic sources. We use persistent homology with a weight rank clique filtration to gain insights into…

Quantitative Methods · Quantitative Biology 2017-05-24 Bernadette J. Stolz , Heather A. Harrington , Mason A. Porter

We propose a method, based on persistent homology, to uncover topological properties of a priori unknown covariates of neuron activity. Our input data consist of spike train measurements of a set of neurons of interest, a candidate list of…

Neurons and Cognition · Quantitative Biology 2015-10-23 Gard Spreemann , Benjamin Dunn , Magnus Bakke Botnan , Nils A. Baas

One of the paramount challenges in neuroscience is to understand the dynamics of individual neurons and how they give rise to network dynamics when interconnected. Historically, researchers have resorted to graph theory, statistics, and…

Neurons and Cognition · Quantitative Biology 2019-02-08 Jean-Baptiste Bardin , Gard Spreemann , Kathryn Hess

Understanding the decision-making processes of large language models is critical given their widespread applications. To achieve this, we aim to connect a formal mathematical framework - zigzag persistence from topological data analysis -…

Computation and Language · Computer Science 2025-06-16 Yuri Gardinazzi , Karthik Viswanathan , Giada Panerai , Alessio Ansuini , Alberto Cazzaniga , Matteo Biagetti

In this paper, we propose Quasi Zigzag Persistent Homology (QZPH) as a framework for analyzing time-varying data by integrating multiparameter persistence and zigzag persistence. To this end, we introduce a stable topological invariant that…

Machine Learning · Computer Science 2026-01-21 Tamal K. Dey , Shreyas N. Samaga

Topological data analysis is an emerging area in exploratory data analysis and data mining. Its main tool, persistent homology, has become a popular technique to study the structure of complex, high-dimensional data. In this paper, we…

Graphics · Computer Science 2017-10-04 Mustafa Hajij , Bei Wang , Carlos Scheidegger , Paul Rosen

We present a novel topological framework for analyzing functional brain signals using time-frequency analysis. By integrating persistent homology with time-frequency representations, we capture multi-scale topological features that…

Neurons and Cognition · Quantitative Biology 2025-04-23 Moo K. Chung , Aaron F. Struck

The theory of zigzag persistence is a substantial extension of persistent homology, and its development has enabled the investigation of several unexplored avenues in the area of topological data analysis. In this paper, we discuss three…

Computational Geometry · Computer Science 2011-08-18 Andrew Tausz , Gunnar Carlsson

We use methods from computational algebraic topology to study functional brain networks, in which nodes represent brain regions and weighted edges encode the similarity of fMRI time series from each region. With these tools, which allow one…

Quantitative Methods · Quantitative Biology 2020-08-27 Bernadette J. Stolz , Tegan Emerson , Satu Nahkuri , Mason A. Porter , Heather A. Harrington

We describe a new methodology for studying persistence of topological features across a family of spaces or point-cloud data sets, called zigzag persistence. Building on classical results about quiver representations, zigzag persistence…

Computational Geometry · Computer Science 2008-12-02 Gunnar Carlsson , Vin de Silva

In this article, we introduce a Topological Data Analysis (TDA) pipeline for neural spike train data. Understanding how the brain transforms sensory information into perception and behavior requires analyzing coordinated neural population…

Methodology · Statistics 2025-12-10 Cagatay Ayhan , Audrey N. Nash , Roberto Vincis , Martin Bauer , Richard Bertram , Tom Needham

Living systems exhibit complex yet organized behavior on multiple spatiotemporal scales. To investigate the nature of multiscale coordination in living systems, one needs a meaningful and systematic way to quantify the complex dynamics, a…

Adaptation and Self-Organizing Systems · Physics 2020-03-11 Mengsen Zhang , William D. Kalies , J. A. Scott Kelso , Emmanuelle Tognoli

Zigzag persistent homology is a powerful generalisation of persistent homology that allows one not only to compute persistence diagrams with less noise and using less memory, but also to use persistence in new fields of application.…

Computational Geometry · Computer Science 2016-08-23 Clément Maria , Steve Oudot

This paper presents a mathematically rigorous framework for brain-inspired representation learning founded on the interplay between persistent topological structures and cohomological flows. Neural computation is reformulated as the…

Machine Learning · Computer Science 2025-12-10 Preksha Girish , Rachana Mysore , Mahanthesha U , Shrey Kumar , Shipra Prashant

Topological data analysis provides a set of tools to uncover low-dimensional structure in noisy point clouds. Prominent amongst the tools is persistence homology, which summarizes birth-death times of homological features using data objects…

Methodology · Statistics 2024-02-05 James Matuk , Sebastian Kurtek , Karthik Bharath

In this paper, we propose a novel framework for dynamical analysis of human actions from 3D motion capture data using topological data analysis. We model human actions using the topological features of the attractor of the dynamical system.…

Computational Geometry · Computer Science 2016-03-18 Vinay Venkataraman , Karthikeyan Natesan Ramamurthy , Pavan Turaga

Advances in large-scale neural recordings have expanded our ability to describe the activity of distributed brain circuits. However, understanding how neural population dynamics differ across regions and behavioral contexts remains…

Functional brain connectivity changes dynamically over time, making its representation challenging for learning on non-Euclidean data. We present a framework that encodes dynamic functional connectivity as an image representation of…

Neurons and Cognition · Quantitative Biology 2025-11-14 Peilin He , Tananun Songdechakraiwut

For nearly three decades, spatial games have produced a wealth of insights to the study of behavior and its relation to population structure. However, as different rules and factors are added or altered, the dynamics of spatial models often…

Computer Science and Game Theory · Computer Science 2021-09-30 Jakob Stenseke

Topological data analysis uses tools from topology -- the mathematical area that studies shapes -- to create representations of data. In particular, in persistent homology, one studies one-parameter families of spaces associated with data,…

Machine Learning · Computer Science 2020-12-01 Guido Montúfar , Nina Otter , Yuguang Wang
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