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Large Language Models (LLMs) have transformed natural language processing and hold growing promise for advancing science, healthcare, and decision-making. Yet their training paradigms remain dominated by affirmation-based inference, akin to…

Artificial Intelligence · Computer Science 2025-12-05 Peter B. Walker , Hannah Davidson , Aiden Foster , Matthew Lienert , Thomas Pardue , Dale Russell

Large Language Model (LLM) agents have shown great potential in addressing real-world data science problems. LLM-driven data science agents promise to automate the entire machine learning pipeline, yet their real-world effectiveness remains…

Computation and Language · Computer Science 2025-10-09 Yixin Ou , Yujie Luo , Jingsheng Zheng , Lanning Wei , Zhuoyun Yu , Shuofei Qiao , Jintian Zhang , Da Zheng , Yuren Mao , Yunjun Gao , Huajun Chen , Ningyu Zhang

Although numerous strategies have recently been proposed to enhance the autonomous interaction capabilities of multimodal agents in graphical user interface (GUI), their reliability remains limited when faced with complex or out-of-domain…

Computation and Language · Computer Science 2025-10-06 Pengzhou Cheng , Lingzhong Dong , Zeng Wu , Zongru Wu , Xiangru Tang , Chengwei Qin , Zhuosheng Zhang , Gongshen Liu

Current research on large language model (LLM) agents is fragmented: discussions of conceptual frameworks and methodological principles are frequently intertwined with low-level implementation details, causing both readers and authors to…

Artificial Intelligence · Computer Science 2026-02-10 Haoyu Jia , Kento Kawaharazuka , Kei Okada

As language models (LMs) evolve from chat assistants to long-horizon agents capable of multi-step reasoning and tool use, existing benchmarks remain largely confined to structured or exam-style tasks that fall short of real-world…

This paper formalises the literature on emerging design patterns and paradigms for Large Language Model (LLM)-enabled multi-agent systems (MAS), evaluating their practical utility across various domains. We define key architectural…

Multiagent Systems · Computer Science 2026-01-08 Harri Renney , Maxim N Nethercott , Nathan Renney , Peter Hayes

Foundation models (FMs) such as large language models have revolutionized the field of AI by showing remarkable performance in various tasks. However, they exhibit numerous limitations that prevent their broader adoption in many real-world…

Artificial Intelligence · Computer Science 2024-02-05 Debarun Bhattacharjya , Junkyu Lee , Don Joven Agravante , Balaji Ganesan , Radu Marinescu

As large language model (LLM)-based multi-agent systems scale to handle increasingly complex tasks, balancing structural stability and dynamic adaptability becomes increasingly challenging. Existing systems typically adopt either…

Multiagent Systems · Computer Science 2026-05-26 Haoran Li , Shulun Chen , Shaoyuan Sun , Hanchen Wang

Multi-agent systems powered by large language models exhibit strong capabilities in collaborative problem-solving. However, these systems suffer from substantial knowledge redundancy. Agents duplicate efforts in retrieval and reasoning…

Graphics · Computer Science 2026-02-27 Heng Zhang , Yuling Shi , Xiaodong Gu , Haochen You , Zijian Zhang , Lubin Gan , Yilei Yuan , Jin Huang

With the rapid development of Large Language Models (LLMs), AI agents have demonstrated increasing proficiency in scientific tasks, ranging from hypothesis generation and experimental design to manuscript writing. Such agent systems are…

The automation of chemical research through self-driving laboratories (SDLs) promises to accelerate scientific discovery, yet the reliability and granular performance of the underlying AI agents remain critical, under-examined challenges.…

Artificial Intelligence · Computer Science 2025-10-01 Gihan Panapitiya , Emily Saldanha , Heather Job , Olivia Hess

Large Language Models (LLMs) have demonstrated potential in automating scientific ideation, yet current approaches relying on iterative prompting or complex multi-agent architectures often suffer from hallucination or computational…

Recently, multimodal large language models (MLLMs) have been widely applied to reasoning tasks. However, they suffer from limited multi-rationale semantic modeling, insufficient logical robustness, and are susceptible to misleading…

Artificial Intelligence · Computer Science 2025-12-08 Chuang Yu , Jinmiao Zhao , Mingxuan Zhao , Yunpeng Liu , Xiujun Shu , Yuanhao Feng , Bo Wang , Xiangyu Yue

The rise of multi-agent systems powered by large language models (LLMs) and specialized reasoning agents exposes fundamental limitations in today's data management architectures. Traditional databases and data fabrics were designed for…

Multiagent Systems · Computer Science 2025-12-11 Ioana Giurgiu , Michael E. Nidd

Recent advances in large language models (LLMs) have enabled a new class of AI agents that automate multiple stages of the data science workflow by integrating planning, tool use, and multimodal reasoning across text, code, tables, and…

Recent advances in language model (LM) agents and function calling have enabled autonomous, feedback-driven systems to solve problems across various digital domains. To better understand the unique limitations of LM agents, we introduce…

Artificial Intelligence · Computer Science 2025-03-12 Dhruv Gautam , Spandan Garg , Jinu Jang , Neel Sundaresan , Roshanak Zilouchian Moghaddam

Multi-agent LLM frameworks are widely used to accelerate the development of agent systems powered by large language models (LLMs). These frameworks impose distinct architectural structures that govern how agents interact, store information,…

Artificial Intelligence · Computer Science 2026-02-04 Abdelghny Orogat , Ana Rostam , Essam Mansour

Autonomous materials research systems allow scientists to fail smarter, learn faster, and spend less resources in their studies. As these systems grow in number, capability, and complexity, a new challenge arises - how will they work…

Multiagent Systems · Computer Science 2023-03-21 A. Gilad Kusne , Austin McDannald

Recent advanced LLM-powered agent systems have exhibited their remarkable capabilities in tackling complex, long-horizon tasks. Nevertheless, they still suffer from inherent limitations in resource efficiency, context management, and…

Multi-agent systems (MAS) demonstrate clear advantages in tackling complex problems by coordinating diverse agents and external tools. However, most existing orchestration methods rely on static workflows or serial agent scheduling, and are…

Artificial Intelligence · Computer Science 2026-04-21 Wenzhen Yuan , Wutao Xiong , Fanchen Yu , Shengji Tang , Ting Liu , Tao Chen , Peng Ye , Yuzhuo Fu , Wanli Ouyang , Lei Bai
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