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Foundation model agents increasingly operate in multi-agent deployments where a coordinator must decide which agent's response to trust. The standard approach weights agents by their self-reported confidence, but recent evidence shows that…

Machine Learning · Computer Science 2026-05-28 Joss Armstrong

In the context of Visual Question Answering (VQA) and Agentic AI, calibration refers to how closely an AI system's confidence in its answers reflects their actual correctness. This aspect becomes especially important when such systems…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Ayush Pandey , Jai Bardhan , Ishita Jain , Ramya S Hebbalaguppe , Rohan Raju Dhanakshirur , Lovekesh Vig

LLMs often underperform on complex reasoning tasks when relying on a single generation-and-selection pipeline. Inference-time ensemble methods can improve performance by sampling diverse reasoning paths or aggregating multiple candidate…

Machine Learning · Computer Science 2026-02-03 Tong Zhu , Baiting Chen , Jin Zhou , Hua Zhou , Sriram Sankararaman , Xiaowu Dai

This paper introduces a comprehensive framework for the evaluation and validation of generative language models (GLMs), with a focus on Retrieval-Augmented Generation (RAG) systems deployed in high-stakes domains such as banking. GLM…

Computation and Language · Computer Science 2024-12-10 Agus Sudjianto , Aijun Zhang , Srinivas Neppalli , Tarun Joshi , Michal Malohlava

TRUST Agents is a collaborative multi-agent framework for explainable fact verification and fake news detection. Rather than treating verification as a simple true-or-false classification task, the system identifies verifiable claims,…

Artificial Intelligence · Computer Science 2026-04-15 Gautama Shastry Bulusu Venkata , Santhosh Kakarla , Maheedhar Omtri Mohan , Aishwarya Gaddam

Interpreting gene clusters from RNA sequencing (RNA-seq) remains challenging, especially in antimicrobial resistance studies where mechanistic insight is important for hypothesis generation. Existing pathway enrichment methods can summarize…

Quantitative Methods · Quantitative Biology 2026-04-03 Elias Hossain , Mehrdad Shoeibi , Ivan Garibay , Niloofar Yousefi

Accurate healthcare prediction is critical for improving patient outcomes and reducing operational costs. Bolstered by growing reasoning capabilities, large language models (LLMs) offer a promising path to enhance healthcare predictions by…

Artificial Intelligence · Computer Science 2025-11-18 Chuang Zhao , Hui Tang , Hongke Zhao , Xiaofang Zhou , Xiaomeng Li

Clinical evidence synthesis requires identifying relevant trials from large registries and aggregating results that account for population differences. While recent LLM-based approaches have automated components of systematic review, they…

Methodology · Statistics 2026-04-06 Yao Zhao , Zhiyue Zhang , Yanxun Xu

Rigorous evaluation of domain-specific language models requires benchmarks that are comprehensive, contamination-resistant, and maintainable. Static, manually curated datasets do not satisfy these properties. We present a graph-based…

Artificial Intelligence · Computer Science 2026-05-18 Jessica M. Lundin , Usman Nasir Nakakana , Guillaume Chabot-Couture

Evaluating large language models (LLM) in clinical scenarios is crucial to assessing their potential clinical utility. Existing benchmarks rely heavily on static question-answering, which does not accurately depict the complex, sequential…

Human-Computer Interaction · Computer Science 2025-05-27 Samuel Schmidgall , Rojin Ziaei , Carl Harris , Eduardo Reis , Jeffrey Jopling , Michael Moor

Routinely collected clinical blood tests are an emerging molecular data source for large-scale biomedical research but inherently feature irregular sampling and informative observation. Traditional approaches rely on imputation, which can…

Quantitative Methods · Quantitative Biology 2025-03-20 Andrea Zerio , Maya Bechler-Speicher , Tine Jess , Aleksejs Sazonovs

Large language model agents increasingly operate through environment-facing scaffolds that expose files, web pages, APIs, and logs. These observations influence tool use, state tracking, and action sequencing, yet their reliability and…

Artificial Intelligence · Computer Science 2026-05-13 Strick Sheng , Ziyue Wang , Liyi Zhou

Large language models (LLMs) have been widely deployed as autonomous agents capable of following user instructions and making decisions in real-world applications. Previous studies have made notable progress in benchmarking the instruction…

Computation and Language · Computer Science 2025-06-18 Lingxiao Diao , Xinyue Xu , Wanxuan Sun , Cheng Yang , Zhuosheng Zhang

Reinforcement learning (RL) has become a central post-training paradigm for large language models (LLMs), but its performance is highly sensitive to the quality of training problems. This sensitivity stems from the non-stationarity of RL:…

Machine Learning · Computer Science 2026-02-26 Ningyuan Yang , Weihua Du , Weiwei Sun , Sean Welleck , Yiming Yang

Recent research in retrieval-augmented generation (RAG) has concentrated on retrieving useful information from candidate documents. However, numerous methodologies frequently neglect the calibration capabilities of large language models…

Computation and Language · Computer Science 2025-06-23 Guanhua Chen , Yutong Yao , Lidia S. Chao , Xuebo Liu , Derek F. Wong

Retrieval-Augmented Generation (RAG) significantly improves the factuality of Large Language Models (LLMs), yet standard pipelines often lack mechanisms to verify inter- mediate reasoning, leaving them vulnerable to hallucinations in…

Computation and Language · Computer Science 2026-03-12 Eeham Khan , Luis Rodriguez , Marc Queudot

Machine learning techniques have been widely used in natural language processing (NLP). However, as revealed by many recent studies, machine learning models often inherit and amplify the societal biases in data. Various metrics have been…

Computation and Language · Computer Science 2020-10-07 Jieyu Zhao , Kai-Wei Chang

Multi-agent systems achieve state-of-the-art outcomes through peer collaboration. However, when an agent in the pipeline silently drops a constraint, the system's final output may look correct even though the reasoning chain was quietly…

Reliable uncertainty quantification (UQ) is essential in medical AI. Evidential Deep Learning (EDL) offers a computationally efficient way to quantify model uncertainty alongside predictions, unlike traditional methods such as Monte Carlo…

Generative retrieval shed light on a new paradigm of document retrieval, aiming to directly generate the identifier of a relevant document for a query. While it takes advantage of bypassing the construction of auxiliary index structures,…

Information Retrieval · Computer Science 2025-06-03 Sunkyung Lee , Minjin Choi , Jongwuk Lee