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Our research has shown that schedules can be built mimicking a human scheduler by using a set of rules that involve domain knowledge. This chapter presents a Bayesian Optimization Algorithm (BOA) for the nurse scheduling problem that…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Jingpeng Li , Uwe Aickelin

Bayesian optimization (BO) is one of the most effective methods for closed-loop experimental design and black-box optimization. However, a key limitation of BO is that it is an inherently sequential algorithm (one experiment is proposed per…

Machine Learning · Statistics 2023-11-21 Leonardo D. González , Victor M. Zavala

Cognitive diagnosis plays a vital role in modern intelligent education platforms to reveal students' proficiency in knowledge concepts for subsequent adaptive tasks. However, due to the requirement of high model interpretability, existing…

Neural and Evolutionary Computing · Computer Science 2023-07-11 Shangshang Yang , Haiping Ma , Cheng Zhen , Ye Tian , Limiao Zhang , Yaochu Jin , Xingyi Zhang

To enable emerging applications such as deep machine learning and graph processing, 3D network-on-chip (NoC) enabled heterogeneous manycore platforms that can integrate many processing elements (PEs) are needed. However, designing such…

Machine Learning · Computer Science 2023-03-14 Sirui Qi , Yingheng Li , Sudeep Pasricha , Ryan Gary Kim

Physics-informed neural networks (PINNs) is becoming a popular alternative method for solving partial differential equations (PDEs). However, they require dedicated manual modifications to the hyperparameters of the network, the sampling…

Computational Engineering, Finance, and Science · Computer Science 2025-04-15 Rui Zhang , Liang Li , Stéphane Lanteri , Hao Kang , Jiaqi Li

The dose delivered to the planning target volume by proton beams is highly conformal, sparing organs at risk and normal tissues. New treatment planning systems adapted to spot scanning techniques have been recently proposed to…

Medical Physics · Physics 2022-05-18 François Smekens , Nicolas Freud , Bruno Sixou , Guillaume Beslon , Jean M Létang

We propose a novel Bayesian optimization (BO) procedure aimed at identifying the ``profile optima'' of a deterministic black-box computer simulation that has a single control parameter and multiple nuisance parameters. The profile optima…

Methodology · Statistics 2025-12-30 Courtney Kyger , James Fernandez , John A. Grunenwald , James Braun , Annie Booth

Deep learning has been widely used for protein engineering. However, it is limited by the lack of sufficient experimental data to train an accurate model for predicting the functional fitness of high-order mutants. Here, we develop SESNet,…

Quantitative Methods · Quantitative Biology 2023-04-10 Mingchen Li , Liqi Kang , Yi Xiong , Yu Guang Wang , Guisheng Fan , Pan Tan , Liang Hong

The Horse Herd Optimization Algorithm (HOA) is a new meta-heuristic algorithm based on the behaviors of horses at different ages. The HOA was introduced recently to solve complex and high-dimensional problems. This paper proposes a binary…

Machine Learning · Computer Science 2023-11-30 Niloufar Mehrabi , Sayed Pedram Haeri Boroujeni , Elnaz Pashaei

A large number of protein sequences are becoming available through the application of novel high-throughput sequencing technologies. Experimental functional characterization of these proteins is time-consuming and expensive, and is often…

Genomics · Quantitative Biology 2017-09-28 Maxat Kulmanov , Mohammed Asif Khan , Robert Hoehndorf

This study introduces a framework that integrates nonlinear feature extraction, classification, and efficient optimization. First, kernel principal component analysis with a radial basis function kernel reduces dimensionality while…

Machine Learning · Computer Science 2025-06-23 Iliyas Ibrahim Iliyas , Souley Boukari , Abdulsalam Yau Gital

Designing RNA molecules that interact with specific proteins is a critical challenge in experimental and computational biology. Existing computational approaches require a substantial amount of previously known interacting RNA sequences for…

Machine Learning · Computer Science 2026-04-17 Roman Klypa , Alberto Bietti , Sergei Grudinin

Optimization strategies driven by machine learning, such as Bayesian optimization, are being explored across experimental sciences as an efficient alternative to traditional design of experiment. When combined with automated laboratory…

Optimization and Control · Mathematics 2022-10-18 Riley J. Hickman , Matteo Aldeghi , Florian Häse , Alán Aspuru-Guzik

Significant research has been carried out recently to find the optimal path in network routing. Among them, the evolutionary algorithm approach is an area where work is carried out extensively. We in this paper have used particle swarm…

Networking and Internet Architecture · Computer Science 2014-07-22 Kavitha Sooda , T. R. Gopalakrishnan Nair

The paper explores the Biased Random-Key Genetic Algorithm (BRKGA) in the domain of logistics and vehicle routing. Specifically, the application of the algorithm is contextualized within the framework of the Vehicle Routing Problem with…

Neural and Evolutionary Computing · Computer Science 2024-05-02 Paola Festa , Francesca Guerriero , Mauricio G. C. Resende , Edoardo Scalzo

Evolutionary Algorithms (EAs) are often challenging to apply in real-world settings since evolutionary computations involve a large number of evaluations of a typically expensive fitness function. For example, an evaluation could involve…

Neural and Evolutionary Computing · Computer Science 2024-04-08 Mohammed Ghaith Altarabichi , Sławomir Nowaczyk , Sepideh Pashami , Peyman Sheikholharam Mashhadi

An evolutionary search space can be smoothly transformed via a suitable change of basis; however, it can be difficult to determine an appropriate basis. In this paper, a method is proposed to select an optimum basis can be used to simplify…

Neural and Evolutionary Computing · Computer Science 2019-04-22 Junghwan Lee , Yong-Hyuk Kim

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

Genomics · Quantitative Biology 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

Probabilistic programming systems enable users to encode model structure and naturally reason about uncertainties, which can be leveraged towards improved Bayesian optimization (BO) methods. Here we present a probabilistic program embedding…

Artificial Intelligence · Computer Science 2019-02-06 Alexander Lavin

Decision-based attacks (DBA), wherein attackers perturb inputs to spoof learning algorithms by observing solely the output labels, are a type of severe adversarial attacks against Deep Neural Networks (DNNs) requiring minimal knowledge of…

Machine Learning · Computer Science 2023-01-20 Zhuosheng Zhang , Shucheng Yu
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