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Although treatment effects can be estimated from observed outcome distributions obtained from proper randomization in clinical trials, covariate adjustment is recommended to increase precision. For important treatment effects, such as odds…

Methodology · Statistics 2025-07-03 Susanne Dandl , Torsten Hothorn

In a general counting process setting, we consider the problem of obtaining a prognostic on the survival time adjusted on covariates in high-dimension. Towards this end, we construct an estimator of the whole conditional intensity. We…

Statistics Theory · Mathematics 2013-10-15 Sarah Lemler

We propose a class of transformation hazard models for right-censored failure time data. It includes the proportional hazards model (Cox) and the additive hazards model (Lin and Ying) as special cases. Due to the requirement of a…

Statistics Theory · Mathematics 2007-06-13 Gousheng Yin , Joseph G. Ibrahim

The semiparametric linear hazard regression model introduced by McKeague and Sasieni (1994) is an extension of the linear hazard regression model developed by Aalen (1980). Methods of model selection for this type of model are still…

Methodology · Statistics 2026-03-04 Axel Gandy , Nils Lid Hjort

Assuming some regression model, it is common to study the conditional distribution of survival given covariates. Here, we consider the impact of further conditioning, specifically conditioning on a marginal survival function, known or…

Applications · Statistics 2016-10-11 Roxane Duroux , Cécile Chauvel , John O'Quigley

This paper proposes a new extension of the linear failure rate (LFR) model to better capture real-world lifetime data. The model incorporates an additional shape parameter to increase flexibility. It helps model the minimum survival time…

Methodology · Statistics 2026-01-13 Suchismita Das , Akul Ameya , Cahyani Karunia Putri

We introduce new approaches for forecasting IBNR (Incurred But Not Reported) frequencies by leveraging individual claims data, which includes accident date, reporting delay, and possibly additional features for every reported claim. A key…

Methodology · Statistics 2025-10-27 Munir Hiabu , Emil Hofman , Gabriele Pittarello

In biomedical studies, we are often interested in the association between different types of covariates and the times to disease events. Because the relationship between the covariates and event times is often complex, standard survival…

Methodology · Statistics 2024-01-19 Hoi Min Ng , Kin Yau Wong

We propose a functional accelerated failure time model to characterize effects of both functional and scalar covariates on the time to event of interest, and provide regularity conditions to guarantee model identifiability. For efficient…

Methodology · Statistics 2024-02-09 Changyu Liu , Wen Su , Kin-Yat Liu , Guosheng Yin , Xingqiu Zhao

Harrel's concordance index is a commonly used discrimination metric for survival models, particularly for models where the relative ordering of the risk of individuals is time-independent, such as the proportional hazards model. There are…

Methodology · Statistics 2023-06-27 A. Gandy , T. J. Matcham

We apply Gaussian process (GP) regression, which provides a powerful non-parametric probabilistic method of relating inputs to outputs, to survival data consisting of time-to-event and covariate measurements. In this context, the covariates…

Statistics Theory · Mathematics 2014-09-08 James E. Barrett , Anthony C. C. Coolen

Survivorship analysis allows to statistically analyze situations that can be modeled as waiting times to an event. These waiting times are characterized by the cumulative hazard rate, which can be estimated by the Nelson-Aalen estimator or…

Statistics Theory · Mathematics 2019-07-04 Niklas Hohmann

Statistical estimation and inference for marginal hazard models with varying coefficients for multivariate failure time data are important subjects in survival analysis. A local pseudo-partial likelihood procedure is proposed for estimating…

Statistics Theory · Mathematics 2009-09-29 Jianwen Cai , Jianqing Fan , Haibo Zhou , Yong Zhou

Latent class analysis (LCA) is a useful tool to investigate the heterogeneity of a disease population with time-to-event data. We propose a new method based on non-parametric maximum likelihood estimator (NPMLE), which facilitates…

Methodology · Statistics 2022-02-03 Teng Fei , John Hanfelt , Limin Peng

Kernel-based nonparametric hazard rate estimation is considered with a special class of infinite-order kernels that achieves favorable bias and mean square error properties. A fully automatic and adaptive implementation of a density and…

Statistics Theory · Mathematics 2018-10-17 Arthur Berg , Dimitris N Politis , Kagba Suaray , Hui Zeng

The paper deals with generalized functional regression. The aim is to estimate the influence of covariates on observations, drawn from an exponential distribution. The link considered has a semiparametric expression: if we are interested in…

Statistics Theory · Mathematics 2013-09-20 Irène Gannaz

In this short communication, we describe the recent debate on whether the hazard function should be used for causal inference in time-to-event studies and consider three different potential outcomes frameworks (by Rubin, Robins, and Pearl,…

Statistics Theory · Mathematics 2023-10-20 Andrew Ying , Ronghui Xu

This paper focuses on nonparametric statistical inference of the hazard rate function of discrete distributions based on $\delta$-record data. We derive the explicit expression of the maximum likelihood estimator and determine its exact…

Statistics Theory · Mathematics 2025-04-03 Martín Alcalde , Miguel Lafuente , F. Javier López , Lina Maldonado , Gerardo Sanz

We find that the CAPM fails to explain the small firm effect even if its non-parametric form is used which allows time-varying risk and non-linearity in the pricing function. Furthermore, the linearity of the CAPM can be rejected, thus the…

Pricing of Securities · Quantitative Finance 2017-03-29 Peter Erdos , Mihaly Ormos , David Zibriczky

Hazard rate functions of natural and manufactured systems often show a bathtub shaped failure rate. A high early rate of failures is followed by an extended period of useful working life where failures are rare, and finally the failure rate…

Applications · Statistics 2023-05-16 Richard Arnold , Stefanka Chukova , Yu Hayakawa
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