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Recently, deep feedforward neural networks have achieved considerable success in modeling biological sensory processing, in terms of reproducing the input-output map of sensory neurons. However, such models raise profound questions about…

Neurons and Cognition · Quantitative Biology 2019-12-16 Hidenori Tanaka , Aran Nayebi , Niru Maheswaranathan , Lane McIntosh , Stephen A. Baccus , Surya Ganguli

Neuromorphic computing seeks to replicate the remarkable efficiency, flexibility, and adaptability of the human brain in artificial systems. Unlike conventional digital approaches, which suffer from the Von Neumann bottleneck and depend on…

Artificial Intelligence · Computer Science 2025-11-04 Marcel van Gerven

Human consciousness has been a long-lasting mystery for centuries, while machine intelligence and consciousness is an arduous pursuit. Researchers have developed diverse theories for interpreting the consciousness phenomenon in human brains…

Neurons and Cognition · Quantitative Biology 2023-09-20 Zihan Ding , Xiaoxi Wei , Yidan Xu

Adolescence is marked by rapid development of executive function. Mounting evidence suggests that executive function in adults may be driven by dynamic control of neurophysiological processes. Yet, how these dynamics evolve over adolescence…

Neurons and Cognition · Quantitative Biology 2015-10-30 John D. Medaglia , Theodore D. Satterthwaite , Tyler M. Moore , Kosha Ruparel , Ruben C. Gur , Raquel E. Gur , Danielle S. Bassett

The last decades saw dramatic progress in brain research. These advances were often buttressed by probing single variables to make circumscribed discoveries, typically through null hypothesis significance testing. New ways for generating…

Neurons and Cognition · Quantitative Biology 2019-03-26 Danilo Bzdok , John Ioannidis

Recent advances in network science, applied to \textit{in vivo} brain recordings, have paved the way for better understanding of the structure and function of the brain. However, despite its obvious usefulness in neuroscience, traditional…

Neurons and Cognition · Quantitative Biology 2025-02-03 Vesna Vuksanovic

Experimental results in recent years have shown that adult neurogenesis is a significant phenomenon in the mammalian brain. Little is known, however, about the functional role played by the generation and destruction of neurons in the…

Neurons and Cognition · Quantitative Biology 2009-11-10 Guillermo A. Cecchi , Marcelo O. Magnasco

Age is an important variable to describe the expected brain's anatomy status across the normal aging trajectory. The deviation from that normative aging trajectory may provide some insights into neurological diseases. In neuroimaging,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-14 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

The unprecedented extension of the human lifespan necessitates a parallel evolution in how we quantify the quality of aging and its socioeconomic impact. Traditional metrics focusing on Healthspan (years free of disease) overlook the…

Quantitative Methods · Quantitative Biology 2026-03-19 Alex Zhavoronkov , Dominika Wilczok

Despite differences in brain sizes and cognitive niches among mammals, their cerebral cortices posses many common features and regularities. These regularities have been a subject of experimental investigation in neuroanatomy for the last…

Neurons and Cognition · Quantitative Biology 2007-05-23 Jan Karbowski

Researchers in neuroscience have a growing number of datasets available to study the brain, which is made possible by recent technological advances. Given the extent to which the brain has been studied, there is also available ontological…

Artificial Intelligence · Computer Science 2022-02-24 Gaston Zanitti , Yamil Soto , Valentin Iovene , Maria Vanina Martinez , Ricardo Rodriguez , Gerardo Simari , Demian Wassermann

Understanding and predicting the progression of neurodegenerative diseases remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning. However, most available…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Nivetha Jayakumar , Swakshar Deb , Bahram Jafrasteh , Qingyu Zhao , Miaomiao Zhang

It is essential to understand the complex structure of the human brain to develop new treatment approaches for neurodegenerative disorders (NDDs). This review paper comprehensively discusses the challenges associated with modelling the…

Neurons and Cognition · Quantitative Biology 2024-11-01 Hina Shaheen , Roderick Melnik

We offer a general theoretical framework for brain and behavior that is evolutionarily and computationally plausible. The brain in our abstract model is a network of nodes and edges. Although it has some similarities to standard neural…

Artificial Intelligence · Computer Science 2022-04-12 Joseph Y. Halpern , Arnon Lotem

We propose a new theory for aging based on dynamical systems and provide a data-driven computational method to quantify the changes at the cellular level. We use ergodic theory to decompose the dynamics of changes during aging and show that…

Quantitative Methods · Quantitative Biology 2025-04-18 Farhan Khodaee , Rohola Zandie , Yufan Xia , Elazer R. Edelman

Networks of interconnected nodes have long played a key role in Cognitive Science, from artificial neural net- works to spreading activation models of semantic mem- ory. Recently, however, a new Network Science has been developed, providing…

Activity in the human brain moves between diverse functional states to meet the demands of our dynamic environment, but fundamental principles guiding these transitions remain poorly understood. Here, we capitalize on recent advances in…

The field of neuroscience is facing an unprecedented expanse in the volume and diversity of available data. Traditionally, network models have provided key insights into the structure and function of the brain. With the advent of big data…

Neurons and Cognition · Quantitative Biology 2018-02-14 Michael Vaiana , Sarah Muldoon

Cognition and language seem closely related to the human cognitive process, although they have not been studied and investigated in detail. Our brain is too complex to fully comprehend the structures and connectivity, as well as its…

Neurons and Cognition · Quantitative Biology 2022-10-26 Zang-Hee Cho , Sun-Ha Paek , Young-Bo Kim , Taigyoun Cho , Hyejin Jeong , Haigun Lee

Recent advances in agentic AI have led to systems capable of autonomous task execution and language-based reasoning, yet their spatial reasoning abilities remain limited and underexplored, largely constrained to symbolic and sequential…

Artificial Intelligence · Computer Science 2025-09-12 Bui Duc Manh , Soumyaratna Debnath , Zetong Zhang , Shriram Damodaran , Arvind Kumar , Yueyi Zhang , Lu Mi , Erik Cambria , Lin Wang