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Millions of patients suffer from rare diseases around the world. However, the samples of rare diseases are much smaller than those of common diseases. In addition, due to the sensitivity of medical data, hospitals are usually reluctant to…

Machine Learning · Computer Science 2021-12-30 Bingyang Chen , Tao Chen , Xingjie Zeng , Weishan Zhang , Qinghua Lu , Zhaoxiang Hou , Jiehan Zhou , Sumi Helal

Clinical text classification requires choosing between specialized fine-tuned models (BERT variants) and general-purpose large language models (LLMs), yet neither dominates across all instances. We introduce Learning to Defer for clinical…

Computation and Language · Computer Science 2026-04-16 Rishik Kondadadi , John E. Ortega

This paper introduces an approach that combines the language reasoning capabilities of large language models (LLMs) with the benefits of local training to tackle complex, domain-specific tasks. Specifically, the authors demonstrate their…

Computation and Language · Computer Science 2023-08-04 V. K. Cody Bumgardner , Aaron Mullen , Sam Armstrong , Caylin Hickey , Jeff Talbert

Recent advancements in artificial intelligence (AI), particularly foundation models (FMs), have revolutionized medical image analysis, demonstrating strong zero- and few-shot performance across diverse medical imaging tasks, from…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Praveenbalaji Rajendran , Mojtaba Safari , Wenfeng He , Mingzhe Hu , Shansong Wang , Jun Zhou , Xiaofeng Yang

The adoption of machine learning in high-stakes applications such as healthcare and law has lagged in part because predictions are not accompanied by explanations comprehensible to the domain user, who often holds the ultimate…

Large Language Models are being increasingly deployed as the decision-making core of autonomous agents capable of effecting change in external environments. Yet, in conversational benchmarks, which simulate real-world customer-centric issue…

Computation and Language · Computer Science 2026-04-29 Amir Saeidi , Venkatesh Mishra , Souradeep Mukhopadhyay , Gaowen Liu , Ali Payani , Jayanth Srinivasa , Chitta Baral

Feature Engineering (FE) is pivotal in automated machine learning (AutoML) but remains a bottleneck for traditional methods, which operate within rigid search spaces and lack domain awareness. While Large Language Models (LLMs) offer a…

Machine Learning · Computer Science 2026-05-22 Beicheng Xu , Keyao Ding , Wei Liu , Yupeng Lu , Bin Cui

Medical image analysis is essential in modern healthcare. Deep learning has redirected research focus toward complex medical multimodal tasks, including report generation and visual question answering. Traditional task-specific models often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Yiming Shi , Shaoshuai Yang , Xun Zhu , Haoyu Wang , Xiangling Fu , Miao Li , Ji Wu

Medical decision-making is a critical task, where errors can result in serious, potentially life-threatening consequences. While full automation remains challenging, hybrid frameworks that combine machine intelligence with human oversight…

Artificial Intelligence · Computer Science 2025-09-10 Debodeep Banerjee , Burcu Sayin , Stefano Teso , Andrea Passerini

The rise of multimodal large language models (MLLMs) has sparked an unprecedented wave of applications in the field of medical imaging analysis. However, as one of the earliest and most fundamental tasks integrated into this paradigm,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Xun Zhu , Fanbin Mo , Xi Chen , Kaili Zheng , Shaoshuai Yang , Yiming Shi , Jian Gao , Miao Li , Ji Wu

Feature Transformation (FT) is a core data-centric AI task that improves feature space quality to advance downstream predictive performance. However, discovering effective transformations remains challenging due to the large space of…

Computation and Language · Computer Science 2026-03-12 Xinyuan Wang , Kunpeng Liu , Arun Vignesh Malarkkan , Yanjie Fu

Background: As of 2026, Large Language Models (LLMs) demonstrate expert-level medical knowledge. However, deploying them as autonomous "Clinical Agents" remains limited. Current Electronic Medical Records (EMRs) and standards like FHIR are…

Artificial Intelligence · Computer Science 2026-05-26 Takahito Nakajima

High-dimensional data remains a pervasive challenge in machine learning, often undermining model interpretability and computational efficiency. While Large Language Models (LLMs) have shown promise for dimensionality reduction through…

Machine Learning · Computer Science 2025-10-08 Mohamed Bal-Ghaoui , Fayssal Sabri

Object detection, segmentation and classification are three common tasks in medical image analysis. Multi-task deep learning (MTL) tackles these three tasks jointly, which provides several advantages saving computing time and resources and…

Computer Vision and Pattern Recognition · Computer Science 2019-06-06 Fei Gao , Hyunsoo Yoon , Teresa Wu , Xianghua Chu

Inference from tabular data, collections of continuous and categorical variables organized into matrices, is a foundation for modern technology and science. Yet, in contrast to the explosive changes in the rest of AI, the best practice for…

Machine Learning · Computer Science 2026-04-07 Daniel Beaglehole , David Holzmüller , Adityanarayanan Radhakrishnan , Mikhail Belkin

The introduction of Large Language Models (LLMs), and the vast volume of publicly available medical data, amplified the application of NLP to the medical domain. However, LLMs are pretrained on data that are not explicitly relevant to the…

Computation and Language · Computer Science 2023-12-12 Chris Solomou

Modern engineering increasingly relies on vast datasets generated by experiments and simulations, driving a growing demand for efficient, reliable, and broadly applicable modeling strategies. There is also heightened interest in developing…

Artificial Intelligence · Computer Science 2025-10-03 Yang Liu , Zaid Abulawi , Abhiram Garimidi , Doyeong Lim

The increase of available large clinical and experimental datasets has contributed to a substantial amount of important contributions in the area of biomedical image analysis. Image segmentation, which is crucial for any quantitative…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Nikhil Kumar Tomar , Debesh Jha , Michael A. Riegler , Håvard D. Johansen , Dag Johansen , Jens Rittscher , Pål Halvorsen , Sharib Ali

The existing methods for evaluating the medical knowledge of Large Language Models (LLMs) are largely based on atemporal examination-style benchmarks, while in reality, medical knowledge is inherently dynamic and continuously evolves as new…

Machine Learning · Computer Science 2026-05-14 Zihan Guan , Qiao Jin , Guangzhi Xiong , Fangyuan Chen , Mengxuan Hu , Qingyu Chen , Yifan Peng , Zhiyong Lu , Anil Vullikanti

Detecting fraud in financial transactions typically relies on tabular models that demand heavy feature engineering to handle high-dimensional data and offer limited interpretability, making it difficult for humans to understand predictions.…

Machine Learning · Computer Science 2026-04-10 Xuwei Tan , Yao Ma , Xueru Zhang
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