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Large language models (LLMs) have rapidly improved text embeddings for a growing array of natural-language processing tasks. However, their opaqueness and proliferation into scientific domains such as neuroscience have created a growing…

Computation and Language · Computer Science 2024-05-28 Vinamra Benara , Chandan Singh , John X. Morris , Richard Antonello , Ion Stoica , Alexander G. Huth , Jianfeng Gao

Semantic text embedding is essential to many tasks in Natural Language Processing (NLP). While black-box models are capable of generating high-quality embeddings, their lack of interpretability limits their use in tasks that demand…

Computation and Language · Computer Science 2024-10-07 Yiqun Sun , Qiang Huang , Yixuan Tang , Anthony K. H. Tung , Jun Yu

Machine learning models offer powerful predictive capabilities but often lack transparency. Local Interpretable Model-agnostic Explanations (LIME) addresses this by perturbing features and measuring their impact on a model's output. In…

Machine Learning · Computer Science 2024-12-24 Nelson Colón Vargas

Recent advances in large language models (LLMs) and biomedical foundation models (BioFMs) have achieved strong results in biological text reasoning, molecular modeling, and single-cell analysis, yet they remain siloed in disjoint embedding…

Quantitative Methods · Quantitative Biology 2025-10-03 Ching-Huei Tsou , Michal Ozery-Flato , Ella Barkan , Diwakar Mahajan , Ben Shapira

The deductive closure of an ideal knowledge base (KB) contains exactly the logical queries that the KB can answer. However, in practice KBs are both incomplete and over-specified, failing to answer some queries that have real-world answers.…

Machine Learning · Computer Science 2021-02-01 Haitian Sun , Andrew O. Arnold , Tania Bedrax-Weiss , Fernando Pereira , William W. Cohen

Word embeddings have found their way into a wide range of natural language processing tasks including those in the biomedical domain. While these vector representations successfully capture semantic and syntactic word relations, hidden…

Machine learning and especially deep learning have garneredtremendous popularity in recent years due to their increased performanceover other methods. The availability of large amount of data has aidedin the progress of deep learning.…

Machine Learning · Computer Science 2019-09-06 Sharath M. Shankaranarayana , Davor Runje

Despite the great success of word embedding, sentence embedding remains a not-well-solved problem. In this paper, we present a supervised learning framework to exploit sentence embedding for the medical question answering task. The learning…

Computation and Language · Computer Science 2018-11-16 Yu Hao , Xien Liu , Ji Wu , Ping Lv

Nowadays, deep neural networks are being used in many domains because of their high accuracy results. However, they are considered as "black box", means that they are not explainable for humans. On the other hand, in some tasks such as…

Machine Learning · Computer Science 2022-04-08 Niloofar Ranjbar , Reza Safabakhsh

Interpretability of artificial intelligence (AI) methods, particularly deep neural networks, is of great interest. This heightened focus stems from the widespread use of AI-backed systems. These systems, often relying on intricate neural…

Quantum Physics · Physics 2024-11-11 Lirandë Pira , Chris Ferrie

Word embeddings have been shown adept at capturing the semantic and syntactic regularities of the natural language text, as a result of which these representations have found their utility in a wide variety of downstream content analysis…

Computation and Language · Computer Science 2021-03-02 Kishlay Jha

Local Interpretable Model-Agnostic Explanations (LIME) is a popular technique used to increase the interpretability and explainability of black box Machine Learning (ML) algorithms. LIME typically generates an explanation for a single…

Machine Learning · Computer Science 2019-06-26 Muhammad Rehman Zafar , Naimul Mefraz Khan

Medical text embedding models are foundational to a wide array of healthcare applications, ranging from clinical decision support and biomedical information retrieval to medical question answering, yet they remain hampered by two critical…

Computation and Language · Computer Science 2025-08-07 Mohammad Khodadad , Ali Shiraee Kasmaee , Mahdi Astaraki , Hamidreza Mahyar

The recent surge of foundation models in computer vision and natural language processing opens up perspectives in utilizing multi-modal clinical data to train large models with strong generalizability. Yet pathological image datasets often…

Computer Vision and Pattern Recognition · Computer Science 2023-07-28 Yunkun Zhang , Jin Gao , Mu Zhou , Xiaosong Wang , Yu Qiao , Shaoting Zhang , Dequan Wang

We propose Medical Entity Definition-based Sentence Embedding (MED-SE), a novel unsupervised contrastive learning framework designed for clinical texts, which exploits the definitions of medical entities. To this end, we conduct an…

Machine Learning · Computer Science 2022-12-12 Hyeonbin Hwang , Haanju Yoo , Yera Choi

Despite their success, Large-Language Models (LLMs) still face criticism due to their lack of interpretability. Traditional post-hoc interpretation methods, based on attention and gradient-based analysis, offer limited insights as they only…

Computation and Language · Computer Science 2025-07-17 Francesco De Santis , Philippe Bich , Gabriele Ciravegna , Pietro Barbiero , Danilo Giordano , Tania Cerquitelli

Clinical text structuring is a critical and fundamental task for clinical research. Traditional methods such as taskspecific end-to-end models and pipeline models usually suffer from the lack of dataset and error propagation. In this paper,…

Computation and Language · Computer Science 2019-10-23 Jiahui Qiu , Yangming Zhou , Zhiyuan Ma , Tong Ruan , Jinlin Liu , Jing Sun

Clinical decisions are high-stakes and require explicit justification, making model interpretability essential for auditing deep clinical models prior to deployment. As the ecosystem of model architectures and explainability methods…

Machine Learning · Computer Science 2026-03-27 Yongda Fan , John Wu , Andrea Fitzpatrick , Naveen Baskaran , Jimeng Sun , Adam Cross

Biomedical Question Answering aims to obtain an answer to the given question from the biomedical domain. Due to its high requirement of biomedical domain knowledge, it is difficult for the model to learn domain knowledge from limited…

Computation and Language · Computer Science 2022-06-29 Yuxuan Lu , Jingya Yan , Zhixuan Qi , Zhongzheng Ge , Yongping Du

Biomedical question answering often requires decisions from retrieved literature whose relevance, quality, and support for candidate answers are uneven. Most retrieval-augmented large language model (LLM) methods feed this literature to the…

Computation and Language · Computer Science 2026-05-19 Chang Zong , Hao Ning , Siliang Tang , Jie Huang , Jian Wan
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