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In precision medicine, quantitative multi-omic features, topological context, and textual biological knowledge play vital roles in identifying disease-critical signaling pathways and targets. Existing pipelines capture only part of…

Artificial Intelligence · Computer Science 2025-12-17 Heming Zhang , Di Huang , Wenyu Li , Michael Province , Yixin Chen , Philip Payne , Fuhai Li

Large Language Model (LLM)-based agents demonstrate strong reasoning and execution capabilities on complex tasks when guided by structured instructions, commonly referred to as workflows. However, existing workflow-assisted agent serving…

Machine Learning · Computer Science 2026-05-22 Ao Li , Shangpeng Yang , Fahao Chen , Tianheng Xu , Peng Li , Zhou Su

Large language models (LLMs) facilitate the development of autonomous agents. As a core component of such agents, task planning aims to decompose complex natural language requests into concrete, solvable sub-tasks. Since LLM-generated plans…

Machine Learning · Computer Science 2026-03-18 Yu Hao , Qiuyu Wang , Cheng Yang , Yawen Li , Zhiqiang Zhang , Chuan Shi

Given a map description through global traversal navigation instructions (e.g., visiting each room sequentially with action signals such as north, west, etc.), an LLM can often infer the implicit spatial layout of the environment and answer…

Artificial Intelligence · Computer Science 2025-10-07 Puzhen Zhang , Xuyang Chen , Yu Feng , Yuhan Jiang , Liqiu Meng

Large language models (LLMs) and agent-based frameworks have advanced rapidly, enabling diverse applications. Yet, with the proliferation of models and agentic strategies, practitioners face substantial uncertainty in selecting the best…

Computation and Language · Computer Science 2025-10-08 Zheyuan Zhang , Kaiwen Shi , Zhengqing Yuan , Zehong Wang , Tianyi Ma , Keerthiram Murugesan , Vincent Galassi , Chuxu Zhang , Yanfang Ye

Recently, the number of off-the-shelf Large Language Models (LLMs) has exploded with many open-source options. This creates a diverse landscape regarding both serving options (e.g., inference on local hardware vs remote LLM APIs) and model…

Machine Learning · Computer Science 2024-12-18 Dimitrios Sikeridis , Dennis Ramdass , Pranay Pareek

Semantic routers in LLM inference gateways select tools in the critical request path, where every millisecond of added latency compounds across millions of requests. We propose Outcome-Aware Tool Selection (OATS), which interpolates tool…

Machine Learning · Computer Science 2026-03-17 Huamin Chen , Xunzhuo Liu , Junchen Jiang , Bowei He , Xue Liu

We propose a new, training-free method, Graph Reasoning via Retrieval Augmented Framework (GRRAF), that harnesses retrieval-augmented generation (RAG) alongside the code-generation capabilities of large language models (LLMs) to address a…

Artificial Intelligence · Computer Science 2025-09-17 Hanqing Li , Kiran Sheena Jyothi , Henry Liang , Sharika Mahadevan , Diego Klabjan

LLM agents must select tools from large API libraries and order them correctly. Existing methods use semantic similarity for both retrieval and ordering, but ordering depends on inter-tool data dependencies that are absent from tool…

Artificial Intelligence · Computer Science 2026-04-23 Hao Liu , Dongyu Li

Large Language Models (LLMs) excel at multi-step reasoning, yet increasing the structural complexity of inference does not consistently improve system-level returns. Methods such as Tree of Thoughts (ToT), Graph of Thoughts (GoT), and…

Computation and Language · Computer Science 2026-03-09 Yuhang Liu , Ruijie Wang , Yunlong Chu , Bing Hao , Yumeng Lin , Shengzhong Liu , Minglai Shao

The increasing density of many-core architectures necessitates interconnection networks that are both high-performance and fault-resilient. Eisenstein-Jacobi (EJ) networks, with their symmetric 6-regular topology, offer superior topological…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-30 Mohammad Walid Charrwi , Zaid Hussain

Property graphs are widely used in domains such as healthcare, finance, and social networks, but they often contain errors due to inconsistencies, missing data, or schema violations. Traditional rule-based and heuristic-driven graph repair…

Computation and Language · Computer Science 2025-07-08 Hrishikesh Terdalkar , Angela Bonifati , Andrea Mauri

Complex operational workflows coordinating personnel, tools, and information are central to system operations, yet end-to-end automation remains challenging due to extensive human input requirements and limited ability to adapt over time.…

Graph learning aims to convert data into graph representations, which are fundamental to many problems in machine learning for CAD, where circuits, layouts, designs, and optimization states are often modeled as graph-structured objects.…

Machine Learning · Computer Science 2026-05-18 Yongyu Wang

LLM routing is increasingly important for selecting suitable models under diverse user needs and deployment constraints, but its practical effectiveness depends on continual adaptation to emerging queries and newly released models. New-LLM…

Networking and Internet Architecture · Computer Science 2026-05-28 Jingjun Xu , Hongji Pu , Tao Feng , Haozhen Zhang , Jiaxuan You , Ge Liu

Mission planning for a fleet of cooperative autonomous drones in applications that involve serving distributed target points, such as disaster response, environmental monitoring, and surveillance, is challenging, especially under partial…

Multiagent Systems · Computer Science 2025-04-14 Michael Elrod , Niloufar Mehrabi , Rahul Amin , Manveen Kaur , Long Cheng , Jim Martin , Abolfazl Razi

Tool-using large language model (LLM) agents often face a fundamental tension between answer quality and execution cost. Fixed workflows are stable but inflexible, while free-form multi-step reasoning methods such as ReAct may improve task…

Artificial Intelligence · Computer Science 2026-03-23 Boyan Liu , Gongming Zhao , Hongli Xu

Graph Retrieval Augmented Generation (GraphRAG) effectively enhances external knowledge integration capabilities by explicitly modeling knowledge relationships, thereby improving the factual accuracy and generation quality of Large Language…

Artificial Intelligence · Computer Science 2025-06-05 Junqi Gao , Xiang Zou , YIng Ai , Dong Li , Yichen Niu , Biqing Qi , Jianxing Liu

We present a distributed self-adjusting algorithm for skip graphs that minimizes the average routing costs between arbitrary communication pairs by performing topological adaptation to the communication pattern. Our algorithm is fully…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-04-05 Sikder Huq , Sukumar Ghosh

Training deep learning models takes an extremely long execution time and consumes large amounts of computing resources. At the same time, recent research proposed systems and compilers that are expected to decrease deep learning models…

Machine Learning · Computer Science 2022-05-11 Sean Parker , Sami Alabed , Eiko Yoneki