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Reinforcement learning (RL) has become a promising paradigm for optimizing Retrieval-Augmented Generation (RAG) in complex reasoning tasks. However, traditional outcome-based RL approaches often suffer from reward sparsity and inefficient…

Artificial Intelligence · Computer Science 2026-01-30 Zhao Wang , Ziliang Zhao , Zhicheng Dou

Recent advances in reasoning-centric language models have highlighted reinforcement learning (RL) as a promising method for aligning models with verifiable rewards. However, it remains contentious whether RL truly expands a model's…

Computation and Language · Computer Science 2025-06-02 Mingjie Liu , Shizhe Diao , Ximing Lu , Jian Hu , Xin Dong , Yejin Choi , Jan Kautz , Yi Dong

Deep Reinforcement Learning (RL) is remarkably effective in addressing sequential resource allocation problems in domains such as healthcare, public policy, and resource management. However, deep RL policies often lack transparency and…

Machine Learning · Computer Science 2025-02-18 Mauricio Tec , Guojun Xiong , Haichuan Wang , Francesca Dominici , Milind Tambe

Large language models (LLMs) provide excellent text-generation capabilities, but standard prompting and generation methods generally do not lead to intentional or goal-directed agents and might necessitate considerable prompt tuning. This…

Computation and Language · Computer Science 2023-12-01 Marwa Abdulhai , Isadora White , Charlie Snell , Charles Sun , Joey Hong , Yuexiang Zhai , Kelvin Xu , Sergey Levine

Large language models (LLMs) can face factual limitations when responding to time-sensitive queries about recent events that arise after their knowledge thresholds in the training corpus. Existing search-augmented approaches fall into two…

Information Retrieval · Computer Science 2025-06-11 Wentao Shi , Yiqing Shen

Incentivizing the reasoning ability of Multimodal Large Language Models (MLLMs) is essential for medical applications to transparently analyze medical scans and provide reliable diagnosis. However, existing medical MLLMs rely solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Lehan Wang , Yi Qin , Honglong Yang , Xiaomeng Li

In recent years, protein-text models have gained significant attention for their potential in protein generation and understanding. Current approaches focus on integrating protein-related knowledge into large language models through…

Computation and Language · Computer Science 2025-11-11 Juntong Wu , Zijing Liu , He Cao , Hao Li , Bin Feng , Zishan Shu , Ke Yu , Li Yuan , Yu Li

Large language models (LLMs) are probabilistic in nature and perform more reliably when augmented with external information. As complex queries often require multi-step reasoning over the retrieved information, with no clear or…

Information Retrieval · Computer Science 2026-04-10 Roxana Petcu , Evangelos Kanoulas , Maarten de Rijke

Reinforcement Learning (RL) traditionally relies on scalar reward signals, limiting its ability to leverage the rich semantic knowledge often available in real-world tasks. In contrast, humans learn efficiently by combining numerical…

Although RLVR has become an essential component for developing advanced reasoning skills in language models, contemporary studies have documented training plateaus after thousands of optimization steps, i.e., notable decreases in…

Artificial Intelligence · Computer Science 2026-04-08 Fang Wu , Weihao Xuan , Heli Qi , Ximing Lu , Aaron Tu , Li Erran Li , Yejin Choi

Proteins are complex molecules responsible for different functions in nature. Enhancing the functionality of proteins and cellular fitness can significantly impact various industries. However, protein optimization using computational…

Machine Learning · Computer Science 2024-05-30 Minji Lee , Luiz Felipe Vecchietti , Hyunkyu Jung , Hyun Joo Ro , Meeyoung Cha , Ho Min Kim

Language Models (LMs) excel in understanding textual descriptions of proteins, as evident in biomedical question-answering tasks. However, their capability falters with raw protein data, such as amino acid sequences, due to a deficit in…

Quantitative Methods · Quantitative Biology 2024-05-22 Zhiyuan Liu , An Zhang , Hao Fei , Enzhi Zhang , Xiang Wang , Kenji Kawaguchi , Tat-Seng Chua

Knowledge-intensive visual question answering (VQA) requires external knowledge beyond image content, demanding precise visual grounding and coherent integration of visual and textual information. Although multimodal retrieval-augmented…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Changin Choi , Wonseok Lee , Jungmin Ko , Wonjong Rhee

Large language models have made remarkable progress in the field of molecular science, particularly in understanding and generating functional small molecules. This success is largely attributed to the effectiveness of molecular…

Biomolecules · Quantitative Biology 2025-03-14 Zicheng Ma , Chuanliu Fan , Zhicong Wang , Zhenyu Chen , Xiaohan Lin , Yanheng Li , Shihao Feng , Jun Zhang , Ziqiang Cao , Yi Qin Gao

Reasoning-augmented search agents, such as Search-R1, are trained to reason, search, and generate the final answer iteratively. Nevertheless, due to their limited capabilities in reasoning and search, their performance on multi-hop QA…

Computation and Language · Computer Science 2025-10-14 Shu Zhao , Tan Yu , Anbang Xu

Reinforcement Learning (RL) significantly enhances the reasoning abilities of large language models (LLMs), yet applying it to multi-turn agentic tasks remains challenging due to the long-horizon nature of interactions and the stochasticity…

Artificial Intelligence · Computer Science 2026-04-03 Jingyue Gao , Yanjiang Guo , Xiaoshuai Chen , Jianyu Chen

Retrieval-Augmented Language Models (RALMs) represent a classic paradigm where models enhance generative capabilities using external knowledge retrieved via a specialized module. Recent advancements in Agent techniques enable Large Language…

Computation and Language · Computer Science 2025-05-28 Weiqi Wu , Xin Guan , Shen Huang , Yong Jiang , Pengjun Xie , Fei Huang , Jiuxin Cao , Hai Zhao , Jingren Zhou

Large language models (LLMs) are designed to perform a wide range of tasks. To improve their ability to solve complex problems requiring multi-step reasoning, recent research leverages process reward modeling to provide fine-grained…

Computation and Language · Computer Science 2025-09-29 Weixuan Wang , Minghao Wu , Barry Haddow , Alexandra Birch

Predicting protein function from sequence is a central challenge in computational biology. While existing methods rely heavily on structured ontologies or similarity-based techniques, they often lack the flexibility to express…

Computational Engineering, Finance, and Science · Computer Science 2025-10-27 Xiao Fei , Michail Chatzianastasis , Sarah Almeida Carneiro , Hadi Abdine , Lawrence P. Petalidis , Michalis Vazirgiannis

Reinforcement learning has proven its effectiveness in enhancing the reasoning capabilities of large language models. Recent research efforts have progressively extended this paradigm to multimodal reasoning tasks. Due to the inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Ruifeng Yuan , Chenghao Xiao , Sicong Leng , Jianyu Wang , Long Li , Weiwen Xu , Hou Pong Chan , Deli Zhao , Tingyang Xu , Zhongyu Wei , Hao Zhang , Yu Rong