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Investigators often use multi-source data (e.g., multi-center trials, meta-analyses of randomized trials, pooled analyses of observational cohorts) to learn about the effects of interventions in subgroups of some well-defined target…

Methodology · Statistics 2024-02-06 Guanbo Wang , Alexander Levis , Jon Steingrimsson , Issa Dahabreh

In randomized clinical trials, adjustments for baseline covariates at both design and analysis stages are highly encouraged by regulatory agencies. A recent trend is to use a model-assisted approach for covariate adjustment to gain…

Methodology · Statistics 2021-07-14 Ting Ye , Jun Shao , Yanyao Yi , Qingyuan Zhao

Ensembles depend on diversity for improved performance. Many ensemble training methods, therefore, attempt to optimize for diversity, which they almost always define in terms of differences in training set predictions. In this paper,…

Machine Learning · Computer Science 2020-02-10 Andrew Slavin Ross , Weiwei Pan , Leo Anthony Celi , Finale Doshi-Velez

Adaptive data analysis (ADA) involves a dynamic interaction between an analyst and a dataset owner, where the analyst submits queries sequentially, adapting them based on previous answers. This process can become adversarial, as the analyst…

Human-Computer Interaction · Computer Science 2025-01-22 Amir Hossein Hadavi , Mohammad M. Mojahedian , Mohammad Reza Aref

Informative cluster size (ICS) and informative subgroup size (ISS) can distort marginal association estimates when the number of observed units, or their distribution across outcome-defined categories, is related to the outcomes under…

Methodology · Statistics 2026-05-22 Owen Visser , Somnath Datta

Distributed data aggregation is an important task, allowing the decentralized determination of meaningful global properties, that can then be used to direct the execution of other applications. The resulting values result from the…

Distributed, Parallel, and Cluster Computing · Computer Science 2011-10-05 Paulo Jesus , Carlos Baquero , Paulo Sérgio Almeida

Multilevel regression and poststratification (MRP) is a popular method for addressing selection bias in subgroup estimation, with broad applications across fields from social sciences to public health. In this paper, we examine the…

Methodology · Statistics 2023-03-06 Yajuan Si

Unlike the more commonly analyzed ECG or PPG data for activity classification, heart rate time series data is less detailed, often noisier and can contain missing data points. Using the BigIdeasLab_STEP dataset, which includes heart rate…

Machine Learning · Computer Science 2024-08-19 Michael Beekhuizen , Arman Naseri , David Tax , Ivo van der Bilt , Marcel Reinders

In many applications, data cluster. Failing to take the cluster structure into consideration generally leads to underestimated variances of point estimators and inflated type I errors in hypothesis tests. Many circumstance-dependent…

Methodology · Statistics 2025-07-21 Jiahua Chen , Pengfei Li , Yukun Liu , James V. Zidek

Using multiple ion beam analysis measurements, or techniques, combined with self-consistent data processing, generally allows extracting more (or more accurate) information from the measurements than processing separately data from single…

Data Analysis, Statistics and Probability · Physics 2022-11-23 Tiago F. Silva , Cleber L. Rodrigues , Manfredo H. Tabacniks , Udo von Toussaint , Matej Mayer

A population-averaged additive subdistribution hazards model is proposed to assess the marginal effects of covariates on the cumulative incidence function and to analyze correlated failure time data subject to competing risks. This approach…

Methodology · Statistics 2023-08-23 Xinyuan Chen , Denise Esserman , Fan Li

Meta-analysis can be formulated as combining $p$-values across studies into a joint $p$-value function, from which point estimates and confidence intervals can be derived. We extend the meta-analytic estimation framework based on combined…

Methodology · Statistics 2025-10-21 David Kronthaler , Leonhard Held

In high-stakes settings where machine learning models are used to automate decision-making about individuals, the presence of algorithmic bias can exacerbate systemic harm to certain subgroups of people. These biases often stem from the…

Machine Learning · Computer Science 2026-04-07 Erin Tan , Judy Hanwen Shen , Irene Y. Chen

AI models for medical diagnosis often exhibit uneven performance across patient populations due to heterogeneity in disease prevalence, imaging appearance, and clinical risk profiles. Existing algorithmic fairness approaches typically seek…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Gelei Xu , Yuying Duan , Jun Xia , Ruining Deng , Wei Jin , Yiyu Shi

Algorithmic differentiation (AD) has become increasingly capable and straightforward to use. However, AD is inefficient when applied directly to solvers, a feature of most engineering analyses. We can leverage implicit differentiation to…

Optimization and Control · Mathematics 2023-06-28 Andrew Ning , Taylor McDonnell

As artificial intelligence and machine learning tools become more accessible, and scientists face new obstacles to data collection (e.g., rising costs, declining survey response rates), researchers increasingly use predictions from…

Machine Learning · Statistics 2025-12-08 Stephen Salerno , Kentaro Hoffman , Awan Afiaz , Anna Neufeld , Tyler H. McCormick , Jeffrey T. Leek

The importance of accurately quantifying forecast uncertainty has motivated much recent research on probabilistic forecasting. In particular, a variety of deep learning approaches has been proposed, with forecast distributions obtained as…

Machine Learning · Statistics 2024-11-11 Benedikt Schulz , Lutz Köhler , Sebastian Lerch

Adam-type optimizers, as a class of adaptive moment estimation methods with the exponential moving average scheme, have been successfully used in many applications of deep learning. Such methods are appealing due to the capability on…

Machine Learning · Computer Science 2020-12-17 Bingxin Zhou , Xuebin Zheng , Junbin Gao

Most information dynamics and statistical causal analysis frameworks rely on the common intuition that causal interactions are intrinsically pairwise -- every 'cause' variable has an associated 'effect' variable, so that a 'causal arrow'…

Neurons and Cognition · Quantitative Biology 2019-09-06 Pedro A. M. Mediano , Fernando Rosas , Robin L. Carhart-Harris , Anil K. Seth , Adam B. Barrett

Anomaly detection (AD) plays an important role in numerous applications. We focus on two understudied aspects of AD that are critical for integration into real-world applications. First, most AD methods cannot incorporate labeled data that…

Machine Learning · Computer Science 2023-06-06 Chun-Hao Chang , Jinsung Yoon , Sercan Arik , Madeleine Udell , Tomas Pfister