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We consider large-scale studies in which thousands of significance tests are performed simultaneously. In some of these studies, the multiple testing procedure can be severely biased by latent confounding factors such as batch effects and…

Methodology · Statistics 2016-06-21 Jingshu Wang , Qingyuan Zhao , Trevor Hastie , Art B. Owen

Causal discovery aims to infer causal relationships among variables from observational data, typically represented by a directed acyclic graph (DAG). Most existing methods assume independent and identically distributed observations, an…

Methodology · Statistics 2026-03-27 Alex Chen , Qing Zhou

Confounding matters in almost all observational studies that focus on causality. In order to eliminate bias caused by connfounders, oftentimes a substantial number of features need to be collected in the analysis. In this case, large p…

Statistics Theory · Mathematics 2019-12-30 Shinyuu Lee , Yuru Zhu

Hidden confounding remains a central challenge in estimating treatment effects from observational data, as unobserved variables can lead to biased causal estimates. While recent work has explored the use of large language models (LLMs) for…

Computation and Language · Computer Science 2025-07-08 Hao Yang , Haoxuan Li , Luyu Chen , Haoxiang Wang , Xu Chen , Mingming Gong

Claiming causal inferences in network settings necessitates careful consideration of the often complex dependency between outcomes for actors. Of particular importance are treatment spillover or outcome interference effects. We consider…

Methodology · Statistics 2022-07-18 Duncan A. Clark , Mark S. Handcock

Principled reasoning about the identifiability of causal effects from non-experimental data is an important application of graphical causal models. This paper focuses on effects that are identifiable by covariate adjustment, a commonly used…

Artificial Intelligence · Computer Science 2019-01-25 Benito van der Zander , Maciej Liśkiewicz , Johannes Textor

Convolutional Neural Networks (ConvNets) have shown excellent results on many visual classification tasks. With the exception of ImageNet, these datasets are carefully crafted such that objects are well-aligned at similar scales. Naturally,…

Computer Vision and Pattern Recognition · Computer Science 2014-12-17 Angjoo Kanazawa , Abhishek Sharma , David Jacobs

Neural networks represent data as projections on trained weights in a high dimensional manifold. The trained weights act as a knowledge base consisting of causal class dependencies. Inference built on features that identify these…

Machine Learning · Computer Science 2021-03-24 Mohit Prabhushankar , Ghassan AlRegib

Statistical inferences for high-dimensional regression models have been extensively studied for their wide applications ranging from genomics, neuroscience, to economics. However, in practice, there are often potential unmeasured…

Methodology · Statistics 2023-09-12 Jing Ouyang , Kean Ming Tan , Gongjun Xu

Causal graph discovery is a significant problem with applications across various disciplines. However, with observational data alone, the underlying causal graph can only be recovered up to its Markov equivalence class, and further…

Machine Learning · Computer Science 2024-02-14 Davin Choo , Kirankumar Shiragur , Caroline Uhler

This article proposes a novel causal discovery and inference method called GrIVET for a Gaussian directed acyclic graph with unmeasured confounders. GrIVET consists of an order-based causal discovery method and a likelihood-based…

Methodology · Statistics 2023-09-22 Li Chen , Chunlin Li , Xiaotong Shen , Wei Pan

Integrating deep learning and causal discovery has encouraged us to spot that learning causal structures and representations in dialogue and video is full of challenges. We defined These data forms as "Indefinite Data", characterized by…

Machine Learning · Computer Science 2024-01-17 Hang Chen , Xinyu Yang , Keqing Du

The estimation of treatment effects is a pervasive problem in medicine. Existing methods for estimating treatment effects from longitudinal observational data assume that there are no hidden confounders, an assumption that is not testable…

Machine Learning · Computer Science 2020-09-21 Ioana Bica , Ahmed M. Alaa , Mihaela van der Schaar

Structured additive distributional regression models offer a versatile framework for estimating complete conditional distributions by relating all parameters of a parametric distribution to covariates. Although these models efficiently…

Methodology · Statistics 2023-11-14 Jana Kleinemeier , Nadja Klein

Causally insufficient structures (models with latent or hidden variables, or with confounding etc.) of joint probability distributions have been subject of intense study not only in statistics, but also in various AI systems. In AI, belief…

Artificial Intelligence · Computer Science 2018-06-04 Mieczysław A. Kłopotek

Machine learning practice is often impacted by confounders. Confounding can be particularly severe in remote digital health studies where the participants self-select to enter the study. While many different confounding adjustment…

Applications · Statistics 2019-11-14 Elias Chaibub Neto , Meghasyam Tummalacherla , Lara Mangravite , Larsson Omberg

A key challenge in environmental health research is unmeasured spatial confounding, driven by unobserved spatially structured variables that influence both treatment and outcome. A common approach is to fit a spatial regression that models…

Methodology · Statistics 2025-12-23 Sophie M. Woodward , Francesca Dominici , Jose R. Zubizarreta

A fundamental feature of human intelligence is the ability to infer high-level abstractions from low-level sensory data. An essential component of such inference is the ability to discover modularized generative mechanisms. Despite many…

Machine Learning · Computer Science 2023-06-08 Peyman Sheikholharam Mashhadi , Slawomir Nowaczyk

Accurate and reliable prediction has profound implications to a wide range of applications. In this study, we focus on an instance of spatio-temporal learning problem--traffic prediction--to demonstrate an advanced deep learning model…

Machine Learning · Computer Science 2024-08-27 Pingping Dong , Xiao-Lin Wang , Indranil Bose , Kam K. H. Ng , Xiaoning Zhang , Xiaoge Zhang

Causal modeling has been recognized as a potential solution to many challenging problems in machine learning (ML). Here, we describe how a recently proposed counterfactual approach developed to deconfound linear structural causal models can…

Machine Learning · Computer Science 2020-11-23 Elias Chaibub Neto
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