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In digital pathology, Whole Slide Image (WSI) analysis is usually formulated as a Multiple Instance Learning (MIL) problem. Although transformer-based architectures have been used for WSI classification, these methods require modifications…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Juan I. Pisula , Katarzyna Bozek

Unsupervised domain adaptation for medical image segmentation remains a significant challenge due to substantial domain shifts across imaging modalities, such as CT and MRI. While recent vision-language representation learning methods have…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Lalit Maurya , Honghai Liu , Reyer Zwiggelaar

Multimodal survival methods combining gigapixel histology whole-slide images (WSIs) and transcriptomic profiles are particularly promising for patient prognostication and stratification. Current approaches involve tokenizing the WSIs into…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Andrew H. Song , Richard J. Chen , Guillaume Jaume , Anurag J. Vaidya , Alexander S. Baras , Faisal Mahmood

Standard language models employ unique, monolithic embeddings for each token, potentially limiting their ability to capture the multifaceted nature of word meanings. We investigate whether tokens can be more effectively represented through…

Computation and Language · Computer Science 2025-09-24 Kavin R , Pawan Goyal

Vision-Language-Action (VLA) models have shown remarkable promise in robotics manipulation, yet their high computational cost hinders real-time deployment. Existing token pruning methods suffer from a fundamental trade-off: aggressive…

Robotics · Computer Science 2026-05-19 Yixu Feng , Zinan Zhao , Yanxiang Ma , Chenghao Xia , Chengbin Du , Yunke Wang , Chang Xu

Presenting whole slide images (WSIs) as graph will enable a more efficient and accurate learning framework for cancer diagnosis. Due to the fact that a single WSI consists of billions of pixels and there is a lack of vast annotated datasets…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Milan Aryal , Nasim Yahyasoltani

In medical image segmentation tasks, the domain gap caused by the difference in data collection between training and testing data seriously hinders the deployment of pre-trained models in clinical practice. Continual Test-Time Adaptation…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Xiaogang Du , Jiawei Zhang , Tongfei Liu , Tao Lei , Yingbo Wang

Existing WSI analysis methods lie on the consensus that histopathological characteristics of tumors are significant guidance for cancer diagnostics. Particularly, as the evolution of cancers is a continuous process, the correlations and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Tong Shu , Jun Shi , Dongdong Sun , Zhiguo Jiang , Yushan Zheng

Cropping high-resolution document images into multiple sub-images is the most widely used approach for current Multimodal Large Language Models (MLLMs) to do document understanding. Most of current document understanding methods preserve…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Renshan Zhang , Yibo Lyu , Rui Shao , Gongwei Chen , Weili Guan , Liqiang Nie

Multiple instance learning (MIL) has become a preferred method for gigapixel whole slide image (WSI) classification without requiring patch-level annotations. Current MIL research primarily relies on embedding-based approaches, which…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Bryan Wong , Sungrae Hong , Mun Yong Yi

To manage the complexity of transformers in video compression, local attention mechanisms are a practical necessity. The common approach of partitioning frames into patches, however, creates architectural flaws like irregular receptive…

Image and Video Processing · Electrical Eng. & Systems 2025-10-07 Alexander Kopte , André Kaup

State-of-the-art (SOTA) gradient-based adversarial attacks on spiking neural networks (SNNs), which largely rely on extending FGSM and PGD frameworks, face a critical limitation: substantial attack latency from multi-timestep processing,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Donghwa Kang , Doohyun Kim , Sang-Ki Ko , Jinkyu Lee , Hyeongboo Baek , Brent ByungHoon Kang

Foundation models are reshaping computational histopathology, yet their value for whole-slide image retrieval relative to strong patch-based and supervised aggregation baselines remains unclear. We benchmarked ten pipelines on 9,387…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Tianhao Lei , Parsa Esmaeilkhani , Saghir Alfasly , Wataru Uegami , Judy C. Boughey , Matthew P. Goetz , Krishna R. Kalari , H. R. Tizhoosh

Whole slide imaging is routinely adopted for carcinoma diagnosis and prognosis. Abundant experience is required for pathologists to achieve accurate and reliable diagnostic results of whole slide images (WSI). The huge size and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Pingyi Chen , Chenglu Zhu , Sunyi Zheng , Honglin Li , Lin Yang

In this paper, we present LLaVA-Scissor, a training-free token compression strategy designed for video multimodal large language models. Previous methods mostly attempt to compress tokens based on attention scores, but fail to effectively…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Boyuan Sun , Jiaxing Zhao , Xihan Wei , Qibin Hou

Multiple instance learning (MIL) has become the leading approach for extracting discriminative features from whole slide images (WSIs) in computational pathology. Attention-based MIL methods can identify key patches but tend to overlook…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Lubin Gan , Xiaoman Wu , Jing Zhang , Zhifeng Wang , Linhao Qu , Siying Wu , Xiaoyan Sun

Deep learning is a powerful tool for whole slide image (WSI) analysis. Typically, when performing supervised deep learning, a WSI is divided into small patches, trained and the outcomes are aggregated to estimate disease grade. However,…

Computer Vision and Pattern Recognition · Computer Science 2022-05-20 Yi Zheng , Rushin H. Gindra , Emily J. Green , Eric J. Burks , Margrit Betke , Jennifer E. Beane , Vijaya B. Kolachalama

Accurate diagnosis of disease often depends on the exhaustive examination of Whole Slide Images (WSI) at microscopic resolution. Efficient handling of these data-intensive images requires lossy compression techniques. This paper…

Large Language Models (LLMs) have achieved remarkable performance across a wide range of Natural Language Processing (NLP) tasks. However, in long-context scenarios, they face two challenges: high computational cost and information…

Computation and Language · Computer Science 2026-02-10 Jiwei Tang , Zhicheng Zhang , Shunlong Wu , Jingheng Ye , Lichen Bai , Zitai Wang , Tingwei Lu , Lin Hai , Yiming Zhao , Hai-Tao Zheng , Hong-Gee Kim

The multi-scale information among the whole slide images (WSIs) is essential for cancer diagnosis. Although the existing multi-scale vision Transformer has shown its effectiveness for learning multi-scale image representation, it still…

Computer Vision and Pattern Recognition · Computer Science 2023-05-26 Saisai Ding , Juncheng Li , Jun Wang , Shihui Ying , Jun Shi