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Stacking excessive layers in DNN results in highly underdetermined system when training samples are limited, which is very common in medical applications. In this regard, we present a framework capable of deriving an efficient…

Machine Learning · Computer Science 2025-03-04 Seunghun Baek , Injun Choi , Mustafa Dere , Minjeong Kim , Guorong Wu , Won Hwa Kim

Functional magnetic resonance imaging (fMRI) data is characterized by its complexity and high--dimensionality, encompassing signals from various regions of interests (ROIs) that exhibit intricate correlations. Analyzing fMRI data directly…

Applications · Statistics 2024-01-18 Yeseul Jeon , Jeong-Jae Kim , SuMin Yu , Junggu Choi , Sanghoon Han

Early diagnosis of Alzheimer Diagnostics (AD) is a challenging task due to its subtle and complex clinical symptoms. Deep learning-assisted medical diagnosis using image recognition techniques has become an important research topic in this…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Yihao Lin , Ximeng Li , Yan Zhang , Jinshan Tang

There is much recent interest in techniques to accelerate the data acquisition process in MRI by acquiring limited measurements. Often sophisticated reconstruction algorithms are deployed to maintain high image quality in such settings. In…

Image and Video Processing · Electrical Eng. & Systems 2022-05-20 Zhishen Huang , Saiprasad Ravishankar

Live-cell imaging of multiple subcellular structures is essential for understanding subcellular dynamics. However, the conventional multi-color sequential fluorescence microscopy suffers from significant imaging delays and limited number of…

Subcellular Processes · Quantitative Biology 2025-01-13 Mingyang Chen , Luhong Jin , Xuwei Xuan , Defu Yang , Yun Cheng , Ju Zhang

Brain midline delineation can facilitate the clinical evaluation of brain midline shift, which plays an important role in the diagnosis and prognosis of various brain pathology. Nevertheless, there are still great challenges with brain…

Computer Vision and Pattern Recognition · Computer Science 2020-07-13 Shen Wang , Kongming Liang , Yiming Li , Yizhou Yu , Yizhou Wang

The ability to accurately detect onset of dementia is important in the treatment of the disease. Clinically, the diagnosis of Alzheimer Disease (AD) and Mild Cognitive Impairment (MCI) patients are based on an integrated assessment of…

Signal Processing · Electrical Eng. & Systems 2022-11-18 Wan-Ting Hsieh , Jeremy Lefort-Besnard , Hao-Chun Yang , Li-Wei Kuo , Chi-Chun Lee

The human brain is liable to undergo substantial alterations, anatomically and functionally with aging. Cognitive brain aging can either be healthy or degenerative in nature. Such degeneration of cognitive ability can lead to disorders such…

Signal Processing · Electrical Eng. & Systems 2022-06-17 Prerna Singh , Tapan Kumar Gandhi , Lalan Kumar

Deep neural networks have been extensively studied for undersampled MRI reconstruction. While achieving state-of-the-art performance, they are trained and deployed specifically for one anatomy with limited generalization ability to another…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Xinwen Liu , Jing Wang , Feng Liu , S. Kevin Zhou

Visual image reconstruction from functional Magnetic Resonance Imaging (fMRI) is a fundamental task in brain decoding, providing a crucial pathway for understanding human perceptual mechanisms and developing advanced brain-computer…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Yudan Ren , Pengcheng Shi , Zihan Ma , Xiaowei He , Xiao Li

Neurological conditions, such as Alzheimer's Disease, are challenging to diagnose, particularly in the early stages where symptoms closely resemble healthy controls. Existing brain network analysis methods primarily focus on graph-based…

Neurons and Cognition · Quantitative Biology 2025-05-20 Jiaxing Xu , Kai He , Yue Tang , Wei Li , Mengcheng Lan , Xia Dong , Yiping Ke , Mengling Feng

MRI is an inherently slow process, which leads to long scan time for high-resolution imaging. The speed of acquisition can be increased by ignoring parts of the data (undersampling). Consequently, this leads to the degradation of image…

Image and Video Processing · Electrical Eng. & Systems 2022-02-22 Soumick Chatterjee , Mario Breitkopf , Chompunuch Sarasaen , Hadya Yassin , Georg Rose , Andreas Nürnberger , Oliver Speck

Self-supervised learning methods like masked autoencoders (MAE) have shown significant promise in learning robust feature representations, particularly in image reconstruction-based pretraining task. However, their performance is often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Sua Lee , Joonhun Lee , Myungjoo Kang

Deep learning associated with neurological signals is poised to drive major advancements in diverse fields such as medical diagnostics, neurorehabilitation, and brain-computer interfaces. The challenge in harnessing the full potential of…

Signal Processing · Electrical Eng. & Systems 2024-07-08 Di Wu , Siyuan Li , Jie Yang , Mohamad Sawan

Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of fMRI correlation matrix. Most of the work with the FC, however, depends on the way…

Neurons and Cognition · Quantitative Biology 2021-12-09 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

Analysis and quantification of brain structural changes, using Magnetic resonance imaging (MRI), are increasingly used to define novel biomarkers of brain pathologies, such as Alzheimer's disease (AD). Network-based models of the brain have…

To explain individual differences in development, behavior, and cognition, most previous studies focused on projecting resting-state functional MRI (fMRI) based functional connectivity (FC) data into a low-dimensional space via linear…

Neurons and Cognition · Quantitative Biology 2018-11-01 Li Xiao , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

The application of compressed sensing (CS)-enabled data reconstruction for accelerating magnetic resonance imaging (MRI) remains a challenging problem. This is due to the fact that the information lost in k-space from the acceleration mask…

Image and Video Processing · Electrical Eng. & Systems 2023-06-22 Guoyao Shen , Boran Hao , Mengyu Li , Chad W. Farris , Ioannis Ch. Paschalidis , Stephan W. Anderson , Xin Zhang

Structural magnetic resonance imaging (sMRI) provides accurate estimates of the brain's structural organization and learning invariant brain representations from sMRI is an enduring issue in neuroscience. Previous deep representation…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Ning Jiang , Gongshu Wang , Tianyi Yan

Self-supervised pretraining is promising for large-scale neuroimaging, yet the impact of region-aware masking and hybrid sequence modeling remains underexplored. In this work, we introduce Rhamba, a region-aware pretraining framework that…

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