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Post-traumatic epilepsy (PTE) is a life-long complication of traumatic brain injury (TBI) and is a major public health problem that has an estimated incidence that ranges from 2%-50%, depending on the severity of the TBI. Currently, the…

Quantitative Methods · Quantitative Biology 2020-11-17 Md Navid Akbar , Marianna La Rocca , Rachael Garner , Dominique Duncan , Deniz Erdoğmuş

Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions.…

Diffusion MRI tractography technique enables non-invasive visualization of the white matter pathways in the brain. It plays a crucial role in neuroscience and clinical fields by facilitating the study of brain connectivity and neurological…

Computer Vision and Pattern Recognition · Computer Science 2025-03-06 Yiqiong Yang , Yitian Yuan , Baoxing Ren , Ye Wu , Yanqiu Feng , Xinyuan Zhang

Here we present DIVE: Data-driven Inference of Vertexwise Evolution. DIVE is an image-based disease progression model with single-vertex resolution, designed to reconstruct long-term patterns of brain pathology from short-term longitudinal…

Computer Vision and Pattern Recognition · Computer Science 2019-04-05 Razvan V. Marinescu , Arman Eshaghi , Marco Lorenzi , Alexandra L. Young , Neil P. Oxtoby , Sara Garbarino , Sebastian J. Crutch , Daniel C. Alexander

MRI and CT are most widely used medical imaging modalities. It is often necessary to acquire multi-modality images for diagnosis and treatment such as radiotherapy planning. However, multi-modality imaging is not only costly but also…

Image and Video Processing · Electrical Eng. & Systems 2022-10-03 Qing Lyu , Ge Wang

Predicting the risk of developing breast cancer is an important clinical tool to guide early intervention and tailoring personalized screening strategies. Early risk models have limited performance and recently machine learning-based…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Zhengbo Zhou , Dooman Arefan , Margarita Zuley , Jules Sumkin , Shandong Wu

Integrating methods for time-to-event prediction with diagnostic imaging modalities is of considerable interest, as accurate estimates of survival requires accounting for censoring of individuals within the observation period. New methods…

Clinical trials are essential to drug development but time-consuming, costly, and prone to failure. Accurate trial outcome prediction based on historical trial data promises better trial investment decisions and more trial success. Existing…

Machine Learning · Computer Science 2023-04-12 Zifeng Wang , Cao Xiao , Jimeng Sun

Medical head CT-scan imaging has been successfully combined with deep learning for medical diagnostics of head diseases and lesions[1]. State of the art classification models and algorithms for this task usually are based on 3d convolution…

Computer Vision and Pattern Recognition · Computer Science 2020-10-21 Luis Leal , Marvin Castillo , Fernando Juarez , Erick Ramirez , Mildred Aspuac , Diana Letona

In radiation therapy (RT), the reliance on pre-treatment computed tomography (CT) images encounter challenges due to anatomical changes, necessitating adaptive planning. Daily cone-beam CT (CBCT) imaging, pivotal for therapy adjustment,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Joonil Hwang , Sangjoon Park , NaHyeon Park , Seungryong Cho , Jin Sung Kim

The rapid increment of morbidity of brain stroke in the last few years have been a driving force towards fast and accurate segmentation of stroke lesions from brain MRI images. With the recent development of deep-learning, computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2021-10-25 Hritam Basak , Rukhshanda Hussain , Ajay Rana

Lung cancer is a major cause of cancer-related deaths, and early diagnosis and treatment are crucial for improving patients' survival outcomes. In this paper, we propose to employ convolutional neural networks to model the non-linear…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Xiawei Wang , James Sharpnack , Thomas C. M. Lee

While originally designed for image generation, diffusion models have recently shown to provide excellent pretrained feature representations for semantic segmentation. Intrigued by this result, we set out to explore how well…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Rui Gong , Martin Danelljan , Han Sun , Julio Delgado Mangas , Luc Van Gool

A major challenge in the segmentation of medical images is the large inter- and intra-observer variability in annotations provided by multiple experts. To address this challenge, we propose a novel method for multi-expert prediction using…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Tomer Amit , Shmuel Shichrur , Tal Shaharabany , Lior Wolf

Cerebrovascular accident (CVA) or stroke is the rapid loss of brain function due to disturbance in the blood supply to the brain. Statistically, stroke is the second leading cause of death. This has motivated us to suggest a two-tier system…

Machine Learning · Computer Science 2020-03-20 Jerrin Thomas Panachakel , Jeena R. S

Stroke is the top leading causes of death in China (Zhou et al. The Lancet 2019). A dataset from Shanxi Province is used to identify the risk of each patient's at four states low/medium/high/attack and provide the state transition tendency…

Machine Learning · Computer Science 2021-08-03 Jing Ma , Yiyang Sun , Junjie Liu , Huaxiong Huang , Xiaoshuang Zhou , Shixin Xu

When oncologists estimate cancer patient survival, they rely on multimodal data. Even though some multimodal deep learning methods have been proposed in the literature, the majority rely on having two or more independent networks that share…

Image and Video Processing · Electrical Eng. & Systems 2022-09-13 Numan Saeed , Ikboljon Sobirov , Roba Al Majzoub , Mohammad Yaqub

Estimating heterogeneous treatment effect (HTE) for survival outcomes has gained increasing attention, as it captures the variation in treatment efficacy across patients or subgroups in delaying disease progression. However, most existing…

Methodology · Statistics 2025-11-27 Na Bo , Ying Ding

Accurate survival prediction in head and neck cancer (HNC) is essential for guiding clinical decision-making and optimizing treatment strategies. Traditional models, such as Cox proportional hazards, have been widely used but are limited in…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Aiman Farooq , Utkarsh Sharma , Deepak Mishra

Fiber tractography is an important tool of computational neuroscience that enables reconstructing the spatial connectivity and organization of white matter of the brain. Fiber tractography takes advantage of diffusion Magnetic Resonance…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 Tomer Weiss , Sanketh Vedula , Ortal Senouf , Oleg Michailovich , AlexBronstein
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