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In order to streamline the fine-tuning of foundation models, Low-Rank Adapters (LoRAs) have been substantially adopted across various fields, including instruction tuning and domain adaptation. The underlying concept of LoRA involves…

Machine Learning · Computer Science 2025-02-25 Mengyang Sun , Yihao Wang , Tao Feng , Dan Zhang , Yifan Zhu , Jie Tang

Foundation models trained via vision-language pretraining have demonstrated strong zero-shot capabilities across diverse image domains, yet their application to volumetric medical imaging remains limited. We introduce MedCT-VLM: Medical CT…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Thuraya Alzubaidi , Farhad R. Nezami , Muzammil Behzad

Early diagnosis of attention-deficit/hyperactivity disorder (ADHD) in children plays a crucial role in improving outcomes in education and mental health. Diagnosing ADHD using neuroimaging data, however, remains challenging due to…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Jyun-Ping Kao , Shinyeong Rho , Shahar Lazarev , Hyun-Hae Cho , Fangxu Xing , Taehoon Shin , C. -C. Jay Kuo , Jonghye Woo

The rapid advancement of foundation modelslarge-scale neural networks trained on diverse, extensive datasetshas revolutionized artificial intelligence, enabling unprecedented advancements across domains such as natural language processing,…

With the rapid development of Large Language Models (LLMs), Parameter-Efficient Fine-Tuning (PEFT) methods have gained significant attention, which aims to achieve efficient fine-tuning of LLMs with fewer parameters. As a representative…

Machine Learning · Computer Science 2025-05-30 Dacao Zhang , Kun Zhang , Shimao Chu , Le Wu , Xin Li , Si Wei

Foundation models (FMs) show great promise for robust downstream performance across medical imaging tasks and modalities, including cardiac magnetic resonance (CMR), following task-specific adaptation. However, adaptation using single-site…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Joan Perramon-Llussà , Amelia Jiménez-Sánchez , Grzegorz Skorupko , Fotis Avgoustidis , Carlos Martín-Isla , Karim Lekadir , Polyxeni Gkontra

Recent attempts to combine low-rank adaptation (LoRA) with mixture-of-experts (MoE) for multi-task adaptation of Large Language Models (LLMs) often replace whole attention/FFN layers with switch experts or append parallel expert branches,…

Machine Learning · Computer Science 2026-05-14 Wenbing Li , Zikai Song , Hang Zhou , Yunyao Zhang , Junqing Yu , Wei Yang

Low-Rank Adaptation (LoRA) dominates parameter-efficient fine-tuning of large language models, yet most variants target dense architectures. Mixture-of-Experts (MoE) models scale parameters at near-constant per-token compute, and their…

Machine Learning · Computer Science 2026-05-20 Jia Wei , Zhonghao Zhang , Ping Chen , Qianyang li , Yancheng Pan , Shaoxun Wang , Ziyi Qiu , Longxiang Wang

Effectively integrating molecular graph structures with Large Language Models (LLMs) is a key challenge in drug discovery. Most existing multi-modal alignment methods typically process these structures by fine-tuning the LLM or adding a…

Machine Learning · Computer Science 2025-10-15 Tao Yin , Xiaohong Zhang , Jiacheng Zhang , Li Huang , Zhibin Zhang , Yuansong Zeng , Jin Xie , Meng Yan

While Low-Rank Adaptation (LoRA) enables parameter-efficient fine-tuning for Large Language Models (LLMs), its performance often falls short of Full Fine-Tuning (Full FT). Current methods optimize LoRA by initializing with static singular…

Computation and Language · Computer Science 2026-03-04 Chenghao Fan , Zhenyi Lu , Sichen Liu , Chengfeng Gu , Xiaoye Qu , Wei Wei , Yu Cheng

The success of CLIP-like vision-language models (VLMs) on natural images has inspired medical counterparts, yet existing approaches largely fall into two extremes: specialist models trained on single-domain data, which capture…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 M. Arda Aydın , Melih B. Yilmaz , Aykut Koç , Tolga Çukur

Parameter-efficient fine-tuning techniques like Low-Rank Adaptation (LoRA) have revolutionized the adaptation of large language models (LLMs) to diverse tasks. Recent efforts have explored mixtures of LoRA modules for multi-task settings.…

Computation and Language · Computer Science 2024-08-06 Lin Ning , Harsh Lara , Meiqi Guo , Abhinav Rastogi

Parameter-Efficient Fine-Tuning (PEFT) methods like LoRA have significantly improved the adaptation of LLMs to downstream tasks in a resource-efficient manner. However, in multi-task scenarios, challenges such as training imbalance and the…

Computation and Language · Computer Science 2024-10-31 Xujia Wang , Haiyan Zhao , Shuo Wang , Hanqing Wang , Zhiyuan Liu

Multi-modal pre-trained models efficiently extract and fuse features from different modalities with low memory requirements for fine-tuning. Despite this efficiency, their application in disease diagnosis is under-explored. A significant…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Zhiyi Shi , Junsik Kim , Wanhua Li , Yicong Li , Hanspeter Pfister

Low-Rank Adaptation (LoRA) drives research to align its performance with full fine-tuning. However, significant challenges remain: (1) Simply increasing the rank size of LoRA does not effectively capture high-rank information, which leads…

Machine Learning · Computer Science 2024-10-21 Chuanyu Tang , Yilong Chen , Zhenyu Zhang , Junyuan Shang , Wenyuan Zhang , Yong Huang , Tingwen Liu

The demonstrated success of sparsely-gated Mixture-of-Experts (MoE) architectures, exemplified by models such as DeepSeek and Grok, has motivated researchers to investigate their adaptation to diverse domains. In real-world image…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Xiao He , Zhijun Tu , Kun Cheng , Mingrui Zhu , Jie Hu , Nannan Wang , Xinbo Gao

The training and fine-tuning of large language models (LLMs) often involve diverse textual data from multiple sources, which poses challenges due to conflicting gradient directions, hindering optimization and specialization. These…

Computation and Language · Computer Science 2025-02-04 Yinghao Li , Vianne Gao , Chao Zhang , MohamadAli Torkamani

Parameter-efficient tuning (PEFT) techniques like low-rank adaptation (LoRA) offer training efficiency on Large Language Models, but their impact on model performance remains limited. Recent efforts integrate LoRA and Mixture-of-Experts…

Computation and Language · Computer Science 2024-02-14 Chongyang Gao , Kezhen Chen , Jinmeng Rao , Baochen Sun , Ruibo Liu , Daiyi Peng , Yawen Zhang , Xiaoyuan Guo , Jie Yang , VS Subrahmanian

Parameter-efficient transfer learning (PETL) has become a promising paradigm for adapting large-scale vision foundation models to downstream tasks. Typical methods primarily leverage the intrinsic low rank property to make decomposition,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-12 Sinan Du , Guosheng Zhang , Keyao Wang , Yuanrui Wang , Haixiao Yue , Gang Zhang , Errui Ding , Jingdong Wang , Zhengzhuo Xu , Chun Yuan

The rapid evolution of Large Language Models (LLMs) has shifted focus from general-purpose capabilities to domain-specific expertise. However, adapting LLMs to specialized fields such as medicine presents two challenge: (1) the…

Machine Learning · Computer Science 2026-01-14 Yuxin Yang , Aoxiong Zeng , Xiangquan Yang
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