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Multimodal reasoning is a challenging task that requires models to reason across multiple modalities to answer questions. Existing approaches have made progress by incorporating language and visual modalities into a two-stage reasoning…

Artificial Intelligence · Computer Science 2024-07-04 Cheng Tan , Jingxuan Wei , Zhangyang Gao , Linzhuang Sun , Siyuan Li , Ruifeng Guo , Bihui Yu , Stan Z. Li

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

Large language models (LLMs) have shown impressive performance on complex reasoning by leveraging chain-of-thought (CoT) prompting to generate intermediate reasoning chains as the rationale to infer the answer. However, existing CoT studies…

Computation and Language · Computer Science 2024-05-21 Zhuosheng Zhang , Aston Zhang , Mu Li , Hai Zhao , George Karypis , Alex Smola

Large language models in healthcare often produce emotionally flat or opaque responses, failing to provide the transparent reasoning required for clinical trust. We present RECAP (Reflect-Extract-Calibrate-Align-Produce), an inference-time…

Computation and Language · Computer Science 2026-05-05 Adarsh Srinivasan , Jacob Dineen , Muhammad Umar Afzal , Muhammad Uzair Sarfraz , Irbaz B. Riaz , Ben Zhou

Evaluating the clinical correctness and reasoning fidelity of automatically generated medical imaging reports remains a critical yet unresolved challenge. Existing evaluation methods often fail to capture the structured diagnostic logic…

Artificial Intelligence · Computer Science 2026-01-26 Suzhong Fu , Jingqi Dong , Xuan Ding , Rui Sun , Yiming Yang , Shuguang Cui , Zhen Li

Reasoning lies at the heart of intelligence, shaping the ability to make decisions, draw conclusions, and generalize across domains. In artificial intelligence, as systems increasingly operate in open, uncertain, and multimodal…

Access to the right evidence does not guarantee that large language models (LLMs) will reason with it correctly. This gap between retrieval and reasoning is especially concerning in clinical settings, where outputs must align with…

Artificial Intelligence · Computer Science 2025-11-21 Deepthi Potluri , Aby Mammen Mathew , Jeffrey B DeWitt , Alexander L. Rasgon , Yide Hao , Junyuan Hong , Ying Ding

In recent years, cross-modal reasoning (CMR), the process of understanding and reasoning across different modalities, has emerged as a pivotal area with applications spanning from multimedia analysis to healthcare diagnostics. As the…

Artificial Intelligence · Computer Science 2023-09-15 Dizhan Xue , Shengsheng Qian , Zuyi Zhou , Changsheng Xu

Transparency in AI healthcare decision-making is crucial. By incorporating rationales to explain reason for each predicted label, users could understand Large Language Models (LLMs)'s reasoning to make better decision. In this work, we…

Computation and Language · Computer Science 2025-08-25 Khai-Nguyen Nguyen , Khai Le-Duc , Bach Phan Tat , Duy Le , Long Vo-Dang , Truong-Son Hy

While the capabilities and utility of AI systems have advanced, rigorous norms for evaluating these systems have lagged. Grand claims, such as models achieving general reasoning capabilities, are supported with model performance on narrow…

Eye-tracking data reveals valuable insights into users' cognitive states but is difficult to analyze due to its structured, non-linguistic nature. While large language models (LLMs) excel at reasoning over text, they struggle with temporal…

Human-Computer Interaction · Computer Science 2025-07-25 Dongyang Guo , Yasmeen Abdrabou , Enkeleda Thaqi , Enkelejda Kasneci

Reasoning is central to human intelligence, enabling structured problem-solving across diverse tasks. Recent advances in large language models (LLMs) have greatly enhanced their reasoning abilities in arithmetic, commonsense, and symbolic…

Different types of reasoning impose different structural demands on representational systems, yet no systematic account of these demands exists across psychology, AI, and philosophy of mind. I propose a framework identifying four structural…

Artificial Intelligence · Computer Science 2026-04-03 Yiling Wu

Medical vision-language models (VLMs) show strong performance on radiology tasks but often produce fluent yet weakly grounded conclusions due to over-reliance on a dominant modality. We introduce a context-aligned reasoning framework that…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Sumra Khan , Sagar Chhabriya , Aizan Zafar , Sheeraz Arif , Amgad Muneer , Anas Zafar , Shaina Raza , Rizwan Qureshi

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

Human-Computer Interaction · Computer Science 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

Dermatological care via telemedicine often lacks the rich context of in-person visits. Clinicians must make diagnoses based on a handful of images and brief descriptions, without the benefit of physical exams, second opinions, or reference…

Artificial Intelligence · Computer Science 2025-08-27 Karishma Thakrar , Shreyas Basavatia , Akshay Daftardar

Medical dialogue systems have attracted significant attention for their potential to act as medical assistants. Enabling these medical systems to emulate clinicians' diagnostic reasoning process has been the long-standing research focus.…

Computation and Language · Computer Science 2024-06-21 Kaishuai Xu , Yi Cheng , Wenjun Hou , Qiaoyu Tan , Wenjie Li

In this work, we introduce Contextual Analog Logic with Multimodality (CALM). CALM unites symbolic reasoning with neural generation, enabling systems to make context-sensitive decisions grounded in real-world multi-modal data. Background:…

Artificial Intelligence · Computer Science 2025-06-19 Maxwell J. Jacobson , Corey J. Maley , Yexiang Xue

Electrocardiography (ECG) serves as an indispensable diagnostic tool in clinical practice, yet existing multimodal large language models (MLLMs) remain unreliable for ECG interpretation, often producing plausible but clinically incorrect…

Computation and Language · Computer Science 2026-05-26 Jiarui Jin , Haoyu Wang , Xingliang Wu , Xiaocheng Fang , Xiang Lan , Zihan Wang , Deyun Zhang , Bo Liu , Yingying Zhang , Xian Wu , Hongyan Li , Shenda Hong

The ability of deep learning (DL) to improve the practice of medicine and its clinical outcomes faces a looming obstacle: model interpretation. Without description of how outputs are generated, a collaborating physician can neither resolve…

Machine Learning · Computer Science 2020-06-30 Christopher Snyder , Sriram Vishwanath