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Head and neck squamous cell carcinoma (HNSCC) has one of the highest rates of recurrence cases among solid malignancies. Recurrence rates can be reduced by improving positive margins localization. Frozen section analysis (FSA) of resected…

Image and Video Processing · Electrical Eng. & Systems 2025-11-03 Qingyun Yang , Fangjie Li , Jiayi Xu , Zixuan Liu , Sindhura Sridhar , Whitney Jin , Jennifer Du , Jon Heiselman , Michael Miga , Michael Topf , Jie Ying Wu

Deformable registration is one of the most challenging task in the field of medical image analysis, especially for the alignment between different sequences and modalities. In this paper, a non-rigid registration method is proposed for 3D…

Computer Vision and Pattern Recognition · Computer Science 2020-02-27 Xiaoyue Zhang , Weijian Jian , Yu Chen , Shihting Yang

Image-guided surgery collocates patient-specific data with the physical environment to facilitate surgical decision making in real-time. Unfortunately, these guidance systems commonly become compromised by intraoperative soft-tissue…

Image and Video Processing · Electrical Eng. & Systems 2023-06-12 Morgan Ringel , Jon Heiselman , Winona Richey , Ingrid Meszoely , William Jarnagin , Michael Miga

Nonlinear image registration continues to be a fundamentally important tool in medical image analysis. Diagnostic tasks, image-guided surgery and radiotherapy as well as motion analysis all rely heavily on accurate intra-patient alignment.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Mattias P. Heinrich

Deformable image registration is a critical technology in medical image analysis, with broad applications in clinical practice such as disease diagnosis, multi-modal fusion, and surgical navigation. Traditional methods often rely on…

Image and Video Processing · Electrical Eng. & Systems 2026-03-04 Zhengyong Huang , Xingwen Sun , Xuting Chang , Ning Jiang , Yao Wang , Jianfei Sun , Hongbin Han , Yao Sui

This work proposes a multimodal diffeomorphic registration method using Neural Ordinary Differential Equations (Neural ODEs). Nonrigid registration algorithms exhibit tradeoffs between their accuracy, the computational complexity of their…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Salvador Rodriguez-Sanz , Monica Hernandez

While deep learning has achieved significant advances in accuracy for medical image segmentation, its benefits for deformable image registration have so far remained limited to reduced computation times. Previous work has either focused on…

Computer Vision and Pattern Recognition · Computer Science 2018-12-06 Alessa Hering , Sven Kuckertz , Stefan Heldmann , Mattias Heinrich

Image registration is one of the most challenging problems in medical image analysis. In the recent years, deep learning based approaches became quite popular, providing fast and performing registration strategies. In this short paper, we…

Computer Vision and Pattern Recognition · Computer Science 2021-04-12 Théo Estienne , Maria Vakalopoulou , Enzo Battistella , Alexandre Carré , Théophraste Henry , Marvin Lerousseau , Charlotte Robert , Nikos Paragios , Eric Deutsch

Deformable image registration aims to precisely align medical images from different modalities or times. Traditional deep learning methods, while effective, often lack interpretability, real-time observability and adjustment capacity during…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Yongtai Zhuo , Yiqing Shen

Registration of pre-operative and post-recurrence brain images is often needed to evaluate the effectiveness of brain gliomas treatment. While recent deep learning-based deformable registration methods have achieved remarkable success with…

Image and Video Processing · Electrical Eng. & Systems 2022-06-09 Tony C. W. Mok , Albert C. S. Chung

Deformable image registration is a fundamental task in medical image analysis and plays a crucial role in a wide range of clinical applications. Recently, deep learning-based approaches have been widely studied for deformable medical image…

Image and Video Processing · Electrical Eng. & Systems 2023-07-03 Jing Zou , Noémie Debroux , Lihao Liu , Jing Qin , Carola-Bibiane Schönlieb , Angelica I Aviles-Rivero

Unsupervised deformable image registration is one of the challenging tasks in medical imaging. Obtaining a high-quality deformation field while preserving deformation topology remains demanding amid a series of deep-learning-based…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Yi Qin , Xiaomeng Li

Deformable image registration plays a critical role in various tasks of medical image analysis. A successful registration algorithm, either derived from conventional energy optimization or deep networks requires tremendous efforts from…

Computer Vision and Pattern Recognition · Computer Science 2023-08-15 Xin Fan , Zi Li , Ziyang Li , Xiaolin Wang , Risheng Liu , Zhongxuan Luo , Hao Huang

Deformable registration has been one of the pillars of biomedical image computing. Conventional approaches refer to the definition of a similarity criterion that, once endowed with a deformation model and a smoothness constraint, determines…

Computer Vision and Pattern Recognition · Computer Science 2018-09-25 Enzo Ferrante , Puneet K. Dokania , Rafael Marini Silva , Nikos Paragios

Deep-learning-based registration methods emerged as a fast alternative to conventional registration methods. However, these methods often still cannot achieve the same performance as conventional registration methods because they are either…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Alessa Hering , Stephanie Häger , Jan Moltz , Nikolas Lessmann , Stefan Heldmann , Bram van Ginneken

Registration of longitudinal brain MRI scans containing pathologies is challenging due to dramatic changes in tissue appearance. Although there has been progress in developing general-purpose medical image registration techniques, they have…

Deformation field estimation is an important and challenging issue in many medical image registration applications. In recent years, deep learning technique has become a promising approach for simplifying registration problems, and has been…

Computer Vision and Pattern Recognition · Computer Science 2020-04-17 Yujia Zhou , Shumao Pang , Jun Cheng , Yuhang Sun , Yi Wu , Lei Zhao , Yaqin Liu , Zhentai Lu , Wei Yang , Qianjin Feng

We propose LiftReg, a 2D/3D deformable registration approach. LiftReg is a deep registration framework which is trained using sets of digitally reconstructed radiographs (DRR) and computed tomography (CT) image pairs. By using simulated…

Image and Video Processing · Electrical Eng. & Systems 2023-04-05 Lin Tian , Yueh Z. Lee , Raúl San José Estépar , Marc Niethammer

Deformable medical image registration is a fundamental task in medical image analysis with applications in disease diagnosis, treatment planning, and image-guided interventions. Despite significant advances in deep learning based…

Machine Learning · Computer Science 2026-02-10 Muhammad Zafar Iqbal , Ghazanfar Farooq Siddiqui , Anwar Ul Haq , Imran Razzak

Deformable registration continues to be one of the key challenges in medical image analysis. While iconic registration methods have started to benefit from the recent advances in medical deep learning, the same does not yet apply for the…

Computer Vision and Pattern Recognition · Computer Science 2019-09-18 Lasse Hansen , Doris Dittmer , Mattias P. Heinrich